Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Steroid Biology and Action"'
Publikováno v:
Journal of the Endocrine Society
Most reports of cortisol half-life in the literature report a range of 90-130 min, which results are based on descriptive model that assumes mono-exponential decay of a single, total cortisol compartment. Free cortisol half-life has been similarly as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e804bb1ebe2ed5d741da53aa4c167000
http://europepmc.org/articles/PMC7208478
http://europepmc.org/articles/PMC7208478
Autor:
Francesco J. DeMayo, Hong Zhao, Serdar E. Bulun, Tanvi Potluri, John S. Coon, Xia Xu, Matthew Taylor, Stacy A. Kujawa
Publikováno v:
Journal of the Endocrine Society
Introduction: More than one in four men develop symptomatic inguinal hernia, and hernia repair is the most commonly performed general surgical procedure in the US. Despite its prevalence, the molecular mechanisms causing inguinal hernia remain unclea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86710d4463fcef530e64fd265cb6a9b8
http://europepmc.org/articles/PMC7207628
http://europepmc.org/articles/PMC7207628
Publikováno v:
Journal of the Endocrine Society
BACKGROUND: Inguinal hernias are a widespread public health issue and typically diagnosed in one-fourth of all men. Despite hernia repair being the most commonly performed surgery in the US, the mechanisms causing this disease are currently unknown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab87fb82c62898a860645b7acfd58540
http://europepmc.org/articles/PMC7209356
http://europepmc.org/articles/PMC7209356
Autor:
Jayde E. Ruelcke, Thomas Stoll, Nicole Cesana-Nigro, Ahmed Mohamed, Johanna L. Barclay, Warrick J. Inder, Michelle M. Hill, Sahar Keshvari, Brendan J Nolan
Publikováno v:
Journal of the Endocrine Society
Glucocorticoids used in pharmacological doses for the treatment of a variety of medical conditions, and endogenous glucocorticoid excess - Cushing’s syndrome, may result in several adverse effects, but currently there is no clinically useful biomar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31dfad3071c11d65fa8b19e6df5f153d
http://europepmc.org/articles/PMC7209594
http://europepmc.org/articles/PMC7209594
Autor:
Joe Zein, Kewal Asosingh, Jeffrey M McManus, Booki Min, Thi Hong Nga Le, Serpil C. Erzurum, Nima Sharifi
Publikováno v:
Journal of the Endocrine Society
3β-hydroxysteroid dehydrogenase-1 (3βHSD1), catalyzing conversion of dehydroepiandrosterone (DHEA) to Δ 4-androstenedione, is an essential enzyme in the pathway toward production of biologically active androgens such as dihydrotestosterone from th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa8b1638fbb2c20d10218229e50d5c3e
http://europepmc.org/articles/PMC7208899
http://europepmc.org/articles/PMC7208899
Autor:
Matthew J. Budoff, Jenny Pena Dias, Sabina A. Haberlen, Chloe L. Thio, Adrian S. Dobs, Jennifer C. Price, Shehzad Basaria, Jordan E. Lake, Todd T. Brown, Frank J. Palella, Lawrence A. Kingsley
Publikováno v:
Journal of the Endocrine Society
Background: Sex hormone-binding globulin (SHBG) is a glycoprotein that regulates the bioavailability of sex hormones, may directly affect glucose metabolism, and increases with age in the general population. SHBG concentrations are higher in people w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e92cb758c7581864d593350e314aa2
http://europepmc.org/articles/PMC7208560
http://europepmc.org/articles/PMC7208560
Autor:
Jon E. Levine, Hongxin Dong, Serdar E. Bulun, Hong Zhao, John S. Coon, David C. Brooks, C. Mutlu Ercan
Publikováno v:
Journal of the Endocrine Society
Introduction: The biologically active form of estrogen, estradiol (E2), has important organizational roles in brain development and activational roles in adult brain physiology and behavior. It has been proposed that E2 formation in the brain might r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae18e94223e3b5d3086f519b365a266
http://europepmc.org/articles/PMC7207519
http://europepmc.org/articles/PMC7207519
Autor:
Hui Zhou, Hubert W Vesper, Douglas Wirtz, Pokuah Fidelia, Candice Zena Ulmer, Avery Arndt, Smith Bianca, Komal Dahya, Brandon Laughlin, Ashley Ribera, Clark Coffman, Nasim Khoshnam, Lynn Collins, Krista Poynter, Uliana Danilenko, Otoe Sugahara
Publikováno v:
Journal of the Endocrine Society
Laboratory measurements are critical for the correct diagnosis and treatment of patients as well as in the investigation of chronic diseases such as hypogonadism, PCOS, and bone-and kidney-related diseases. Inaccurate measurements can lead to misclas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bb6a6ab6bdd77dfeed212a5f5d5b4b5
http://europepmc.org/articles/PMC7207912
http://europepmc.org/articles/PMC7207912
Autor:
Richard G. Pestell
Publikováno v:
Journal of the Endocrine Society
The estrogen receptor α (ERα) is known to convey both genomic and extra-genomic activities. The extra-nuclear estrogen signaling pathway is thought to involve a membrane-associated estrogen receptor (ERα), which activates PI3-kinase and Akt signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9e0373628ab9a0ed3ee9c05ca15f16e
http://europepmc.org/articles/PMC7207782
http://europepmc.org/articles/PMC7207782
Autor:
Therina du Toit, Amanda C. Swart
Publikováno v:
Journal of the Endocrine Society
The metabolism of 11β-hydroxyandrostenedione (11OHA4), a major adrenal C19 steroid, was first characterised in our in vitro prostate models showing that 11OHA4, catalysed by 11βHSDs, 17βHSDs and 5α-reductases, yields potent androgens, 11keto-test
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54e448d612721fa659f7d0d09eec8fec
http://europepmc.org/articles/PMC7208218
http://europepmc.org/articles/PMC7208218