A Drosophila computational brain model reveals sensorimotor processing.

Autor: Shiu PK; Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA. philshiu@gmail.com.; Eon Systems, San Francisco, CA, USA. philshiu@gmail.com., Sterne GR; Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA.; University of Rochester Medical Center, Department of Biomedical Genetics, New York, NY, USA., Spiller N; Max Planck Florida Institute for Neuroscience, Jupiter, FL, USA., Franconville R; HHMI Janelia Research Campus, Ashburn, VA, USA., Sandoval A; Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA., Zhou J; Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA., Simha N; Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA., Kang CH; Department of Biological Sciences, Sungkyunkwan University, Suwon, South Korea., Yu S; Department of Biological Sciences, Sungkyunkwan University, Suwon, South Korea., Kim JS; Department of Biological Sciences, Sungkyunkwan University, Suwon, South Korea., Dorkenwald S; Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA.; Computer Science Department, Princeton University, Princeton, NJ, USA., Matsliah A; Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA., Schlegel P; Department of Zoology, University of Cambridge, Cambridge, UK.; Neurobiology Division, MRC Laboratory of Molecular Biology, Cambridge, UK., Yu SC; Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA., McKellar CE; Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA., Sterling A; Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA., Costa M; Department of Zoology, University of Cambridge, Cambridge, UK., Eichler K; Computer Science Department, Princeton University, Princeton, NJ, USA., Bates AS; Neurobiology Division, MRC Laboratory of Molecular Biology, Cambridge, UK.; Centre for Neural Circuits and Behaviour, The University of Oxford, Oxford, UK.; Department of Neurobiology and Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA., Eckstein N; HHMI Janelia Research Campus, Ashburn, VA, USA., Funke J; HHMI Janelia Research Campus, Ashburn, VA, USA., Jefferis GSXE; Department of Zoology, University of Cambridge, Cambridge, UK.; Neurobiology Division, MRC Laboratory of Molecular Biology, Cambridge, UK., Murthy M; Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA., Bidaye SS; Max Planck Florida Institute for Neuroscience, Jupiter, FL, USA., Hampel S; Institute of Neurobiology, University of Puerto Rico-Medical Sciences Campus, San Juan, Puerto Rico., Seeds AM; Institute of Neurobiology, University of Puerto Rico-Medical Sciences Campus, San Juan, Puerto Rico., Scott K; Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA.

Publikováno v: Nature [Nature] 2024 Oct; Vol. 634 (8032), pp. 210-219. Date of Electronic Publication: 2024 Oct 02.

The Drosophila homolog of APP promotes Dscam expression to drive axon terminal growth, revealing interaction between Down syndrome genes.

Autor: Pizzano S; Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.; Neuroscience Graduate Program, University of Michigan, Ann Arbor, MI 48109, USA., Sterne GR; Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.; Neuroscience Graduate Program, University of Michigan, Ann Arbor, MI 48109, USA.; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY 14642, USA., Veling MW; Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.; Cellular and Molecular Biology Program, University of Michigan, Ann Arbor, MI 48109, USA., Xu LA; Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA., Hergenreder T; Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA., Ye B; Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.; Neuroscience Graduate Program, University of Michigan, Ann Arbor, MI 48109, USA.; Cellular and Molecular Biology Program, University of Michigan, Ann Arbor, MI 48109, USA.; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA.

Publikováno v: Disease models & mechanisms [Dis Model Mech] 2023 Sep 01; Vol. 16 (9). Date of Electronic Publication: 2023 Sep 15.

A leaky integrate-and-fire computational model based on the connectome of the entire adult Drosophila brain reveals insights into sensorimotor processing.

Autor: Shiu PK; Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA., Sterne GR; Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA.; University of Rochester Medical Center, Department of Biomedical Genetics., Spiller N; Max Planck Florida Institute for Neuroscience, Jupiter, FL, USA., Franconville R; HHMI Janelia Research Campus, Ashburn, USA., Sandoval A; Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA., Zhou J; Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA., Simha N; Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA., Kang CH; Department of Biological Sciences, Sungkyunkwan University, Suwon, 16419, South Korea., Yu S; Department of Biological Sciences, Sungkyunkwan University, Suwon, 16419, South Korea., Kim JS; Department of Biological Sciences, Sungkyunkwan University, Suwon, 16419, South Korea., Dorkenwald S; Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA.; Computer Science Department, Princeton University, Princeton, NJ, USA., Matsliah A; Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA., Schlegel P; Department of Zoology, University of Cambridge.; Neurobiology Division, MRC Laboratory of Molecular Biology, Cambridge., Szi-Chieh Y; Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA., McKellar CE; Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA., Sterling A; Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA., Costa M; Department of Zoology, University of Cambridge., Eichler K; Department of Zoology, University of Cambridge., Jefferis GSXE; Department of Zoology, University of Cambridge.; Neurobiology Division, MRC Laboratory of Molecular Biology, Cambridge., Murthy M; Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA., Bates AS; Neurobiology Division, MRC Laboratory of Molecular Biology, Cambridge.; Centre for Neural Circuits and Behaviour, The University of Oxford.; Department of Neurobiology and Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA., Eckstein N; HHMI Janelia Research Campus, Ashburn, USA., Funke J; HHMI Janelia Research Campus, Ashburn, USA., Bidaye SS; Max Planck Florida Institute for Neuroscience, Jupiter, FL, USA., Hampel S; Institute of Neurobiology, University of Puerto Rico-Medical Sciences Campus, San Juan, Puerto Rico., Seeds AM; Institute of Neurobiology, University of Puerto Rico-Medical Sciences Campus, San Juan, Puerto Rico., Scott K; Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 May 02. Date of Electronic Publication: 2023 May 02.

A searchable image resource of Drosophila GAL4 driver expression patterns with single neuron resolution.

Autor: Meissner GW; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Nern A; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Dorman Z; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., DePasquale GM; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Forster K; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Gibney T; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Hausenfluck JH; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., He Y; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Iyer NA; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Jeter J; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Johnson L; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Johnston RM; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Lee K; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Melton B; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Yarbrough B; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Zugates CT; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Clements J; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Goina C; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Otsuna H; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Rokicki K; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Svirskas RR; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Aso Y; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Card GM; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Dickson BJ; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Ehrhardt E; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Goldammer J; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Ito M; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Kainmueller D; Max-Delbrueck-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany., Korff W; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Mais L; Max-Delbrueck-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany., Minegishi R; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Namiki S; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Rubin GM; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Sterne GR; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Wolff T; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Malkesman O; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States.

Publikováno v: ELife [Elife] 2023 Feb 23; Vol. 12. Date of Electronic Publication: 2023 Feb 23.

Drosophila gustatory projections are segregated by taste modality and connectivity.

Autor: Engert S; University of California, Berkeley, Berkeley, United States.; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Sterne GR; University of California, Berkeley, Berkeley, United States., Bock DD; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States., Scott K; University of California, Berkeley, Berkeley, United States.

Publikováno v: ELife [Elife] 2022 May 25; Vol. 11. Date of Electronic Publication: 2022 May 25.