Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Sternas, L"'
Autor:
Li Y, Wang X, O’Mara E, Dimopoulos MA, Sonneveld P, Weisel KC, Matous J, Siegel DS, Shah JJ, Kueenburg E, Sternas L, Cavanaugh C, Zaki M, Palmisano M, Zhou S
Publikováno v:
Clinical Pharmacology: Advances and Applications, Vol Volume 9, Pp 133-145 (2017)
Yan Li,1 Xiaomin Wang,2 Edward O’Mara,1 Meletios A Dimopoulos,3 Pieter Sonneveld,4 Katja C Weisel,5 Jeffrey Matous,6 David S Siegel,7 Jatin J Shah,8 Elisabeth Kueenburg,9 Lars Sternas,9 Chloe Cavanaugh,9 Mohamed Zaki,9 Maria Palmisano,1 Simon Zhou1
Externí odkaz:
https://doaj.org/article/8582ebb39ceb4fcd9b07b7d44a784b3f
Pomalidomide is an immunomodulatory drug for treatment of relapsed or refractory multiple myeloma (rrMM) in patients who often have comorbid renal conditions. To assess the impact of renal impairment on pomalidomide exposure, a population pharmacokin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::63e1dcb6aaeeea2f6862213dc8dbb73d
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3108132
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3108132
Objectives: Heavily pretreated patients with relapsed and refractory multiple myeloma are susceptible to treatment-related adverse events (AEs). Managing AEs are important to ensure patients continue therapy long enough to receive the best clinical b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::2991ed8e1bdd4ac49a00f95368df13ea
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3125855
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3125855
Patients with relapsed and/or refractory multiple myeloma (RRMM) have poor prognosis. The STRATUS study assessed safety and efficacy of pomalidomide plus low-dose dexamethasone in the largest cohort to date of patients with RRMM. Patients who failed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::c0821c62f8338dc0ad1a4b7c68212edc
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3001397
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3001397
Renal impairment (RI) is a major comorbidity in patients with multiple myeloma (MM). Here we present the pooled safety and efficacy analysis of three clinical trials (MM-002, MM-003, and MM-010) of pomalidomide + low-dose dexamethasone (POM + LoDEX)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::b27ef808ee9b3b6e818c2d644f9a3a67
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3086100
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3086100
Pomalidomide + low-dose dexamethasone is effective and well tolerated for refractory or relapsed and refractory multiple myeloma after bortezomib and lenalidomide failure. The phase III trial MM-003 compared pomalidomide + low-dose dexamethasone with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::2079ba4c30c483964286048f802b255c
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3101448
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3101448
Autor:
Dimopoulos, Ma, Palumbo, A, Corradini, P, Cavo, M, Delforge, M, Weisel, Kc, Ocio, Em, DI RAIMONDO, Francesco, Hansson, M, Simcock, M, Miller, N, Slaughter, A, Peluso, T, Sternas, L, Zaki, Mh, Moreau, P.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______4731::329a85ef4cd70e46d46555e8f4d62569
http://hdl.handle.net/20.500.11769/47613
http://hdl.handle.net/20.500.11769/47613
Summary: In the phase III MM-003 trial, pomalidomide plus low-dose dexamethasone (POM+LoDEX) improved overall survival (OS) versus high-dose dexamethasone (HiDEX) in 455 patients with relapsed and refractory multiple myeloma (RRMM) after treatment wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::b449fbfc0b95ac96db95ec397ab89493
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3125292
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3125292
Autor:
Dimopoulos, Ma, Palumbo, A, Corradini, P, Cavo, M, Delforge, M, Weisel, K, Ocio, E, DI RAIMONDO, Francesco, Oriol, A, Simcock, M, Miller, N, Slaughter, A, Peluso, T, Sternas, L, Zaki, M, Moreau, P.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______4731::57959c03c23f1fc70280a342e92234ad
http://hdl.handle.net/20.500.11769/44950
http://hdl.handle.net/20.500.11769/44950