Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sterling Sawaya"'
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Genetic information is being generated at an increasingly rapid pace, offering advances in science and medicine that are paralleled only by the threats and risk present within the responsible systems. Human genetic information is identifiable and con
Externí odkaz:
https://doaj.org/article/199c41acb79a4d9cb2a80355b5019eef
Autor:
Sterling Sawaya, Andrew Bagshaw, Emmanuel Buschiazzo, Pankaj Kumar, Shantanu Chowdhury, Michael A Black, Neil Gemmell
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e54710 (2013)
Tandem repeats are genomic elements that are prone to changes in repeat number and are thus often polymorphic. These sequences are found at a high density at the start of human genes, in the gene's promoter. Increasing empirical evidence suggests tha
Externí odkaz:
https://doaj.org/article/cfdeef03ade9437ea46767f92685df6b
Publikováno v:
SSRN Electronic Journal.
Advancements in genetics have the ability to rapidly improve medicine, with a number of factors converging to push the integration of genomics into mainstream healthcare. As technologies that use genetic data begin to expand, so does exposure to risk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::370731f88366720dce06471e09345f8c
https://doi.org/10.2139/ssrn.3635050
https://doi.org/10.2139/ssrn.3635050
Autor:
Sterling Sawaya
Genetic information can be highly sensitive and can be used to identify its source. To conceal genetic information, cryptographic methods can be applied to genetic material itself, concealing sensitive information prior to the generation of sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ef834bc147475f7fac18765c5c7c7fc
https://doi.org/10.1101/157685
https://doi.org/10.1101/157685
Publikováno v:
Genome Biology and Evolution
Microsatellites make up ∼3% of the human genome, and there is increasing evidence that some microsatellites can have important functions and can be conserved by selection. To investigate this conservation, we performed a genome-wide analysis of hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98f7f6e5c6f399c945e448ecba9709ce
https://doi.org/10.1093/gbe/evs050
https://doi.org/10.1093/gbe/evs050
Some diseases are caused by genetic loci with a high rate of change, and heritability in complex traits is likely to be partially caused by variation at these loci. These hypermutable elements, such as tandem repeats, change at rates that are orders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c402462e606376dae5073f7bd74e1ae
https://doi.org/10.1101/020909
https://doi.org/10.1101/020909
Autor:
Andrew T. M. Bagshaw, Pankaj Kumar, Neil J. Gemmell, Shantanu Chowdhury, Michael A. Black, Sterling Sawaya, Emmanuel Buschiazzo
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 2, p e54710 (2013)
PLoS ONE, Vol 8, Iss 2, p e54710 (2013)
Tandem repeats are genomic elements that are prone to changes in repeat number and are thus often polymorphic. These sequences are found at a high density at the start of human genes, in the gene's promoter. Increasing empirical evidence suggests tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e48b7e91dae13baad0830938a561cd5
https://pubmed.ncbi.nlm.nih.gov/23405090
https://pubmed.ncbi.nlm.nih.gov/23405090
Publikováno v:
Cyberbiosecurity ISBN: 9783031260339
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bbcd9470f9e23424ecb6dec73405220
https://doi.org/10.1007/978-3-031-26034-6_14
https://doi.org/10.1007/978-3-031-26034-6_14
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461454335
Microsatellites in and around genes have been shown to modulate levels of gene expression in multiple organisms, ranging from bacteria to humans. Here we will discuss promoter microsatellites known to modulate gene expression, with a few key examples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb62dfc400ea3ee04e63a7c68095674e
https://doi.org/10.1007/978-1-4614-5434-2_4
https://doi.org/10.1007/978-1-4614-5434-2_4
Autor:
Sarita Balabhadra, Craig Miller, Sterling Sawaya, Dolph Schluter, Brian R. Summers, Timothy H. Vines, Arianne Albert, Anne K. Knecht, David M. Kingsley
Publikováno v:
Evolution; international journal of organic evolution. 62(1)
The distribution of effect sizes of genes underlying adaptation is unknown (Orr 2005). Are suites of traits that diverged under natural selection controlled by a few pleiotropic genes of large effect (major genes model), by many independently acting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fa27f2456edc3f99d3a98bc5ca8b07c
https://pubmed.ncbi.nlm.nih.gov/18005154
https://pubmed.ncbi.nlm.nih.gov/18005154