Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sterling C Eckard"'
Autor:
Qui T. Phung, Stefan Gerhardy, Mike Reichelt, Michele A. Grimbaldeston, Lucinda W Tam, Patrick Caplazi, Alvin Gogineni, Andrew P. AhYoung, Christian Cox, Robby M. Weimer, Daniel Kirchhofer, Jason A. Hackney, Sterling C Eckard, Wyne P. Lee, Robert J. Newman, Merone Roose-Girma, Jennie R. Lill, Anand Kumar Katakam, Hongkang Xi, Juan Zhang, Aditya Murthy, S. Jack Lin, Paolo Manzanillo, Menno Van Lookeren Campagne
Publikováno v:
Communications Biology
Communications Biology, Vol 3, Iss 1, Pp 1-13 (2020)
Communications Biology, Vol 3, Iss 1, Pp 1-13 (2020)
Vascular leakage, or edema, is a serious complication of acute allergic reactions. Vascular leakage is triggered by the release of histamine and serotonin from granules within tissue-resident mast cells. Here, we show that expression of Neutrophil Se
Autor:
Daniel B. Stetson, Yanick J. Crow, Gillian I. Rice, Sterling C Eckard, Catherine Badens, Alexandre Fabre, Jane Hartley, Elizabeth E. Gray
Publikováno v:
Nature immunology
Sensors of the innate immune system that detect intracellular nucleic acids must be regulated to prevent inappropriate activation by endogenous DNA and RNA. The exonuclease Trex1 regulates the DNA-sensing pathway by metabolizing potential DNA ligands
Autor:
Bruno Canard, Jay R. Hesselberth, Michael Gale, David J. Barton, Hilario J. Ramos, Jonathan M. Clingan, Daniel B. Stetson, Jaime Guillén, Sterling C Eckard, Daphne A. Cooper
Publikováno v:
Cancer Immunology Research. 4:B133-B133
Intracellular detection of RNA or DNA triggers distinct sensors that protect against virus infection: RNA activates the RIG-I-like Receptor (RLR)-MAVS pathway, whereas DNA activates the cyclic GMP-AMP Synthase (cGAS)-STING pathway. In addition, the o