RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response

Autor: Penn-Nicholson, A, Mbandi, SK, Thompson, E, Mendelsohn, SC, Suliman, S, Chegou, NN, Malherbe, ST, Darboe, F, Erasmus, M, Hanekom, WA, Bilek, N, Fisher, M, Kaufmann, SHE, Winter, J, Murphy, M, Wood, R, Morrow, C, Van Rhijn, I, Moody, B, Murray, M, Andrade, BB, Sterling, TR, Sutherland, J, Naidoo, K, Padayatchi, N, Walzl, G, Hatherill, M, Zak, D, Scriba, TJ, Kafaar, F, Workman, L, Mulenga, H, Hughes, EJ, Xasa, O, Veldsman, A, Cloete, Y, Abrahams, D, Moyo, S, Gelderbloem, S, Tameris, M, Geldenhuys, H, Ehrlich, R, Verver, S, Geiter, L, Black, GF, van der Spuy, G, Stanley, K, Kriel, M, Du Plessis, N, Nene, N, Roberts, T, Kleynhans, L, Gutschmidt, A, Smith, B, Loxton, AG, Tromp, G, Tabb, D, Ottenhoff, THM, Klein, MR, Haks, MC, Franken, KLMC, Geluk, A, van Meijgaarden, KE, Joosten, SA, Boom, WH, Thiel, B, Mayanja-Kizza, H, Joloba, M, Zalwango, S, Nsereko, M, Okwera, B, Kisingo, H, Parida, SK, Golinski, R, Maertzdorf, J, Weiner, J, Jacobson, M, Dockrell, H, Smith, S, Gorak-Stolinska, P, Hur, YG, Lalor, M, Lee, JS, Crampin, AC, French, N, Ngwira, B, Ben-Smith, A, Watkins, K, Ambrose, L, Simukonda, F, Mvula, H, Chilongo, F, Saul, J, Branson, K, Mahomed, H, Downing, K

Publikováno v: Scientific reports
Scientific reports, vol 10, iss 1
Scientific Reports
Scientific reports, 10(1):8629. Nature Publishing Group
Scientific Reports, Vol 10, Iss 1, Pp 1-21 (2020)
Scientific Reports, 10(1). NATURE PUBLISHING GROUP
Scientific Reports, 10(1). NLM (Medline)
Scientific Reports, 10(1):8629. Nature Publishing Group

Improved tuberculosis diagnostics and tools for monitoring treatment response are urgently needed. We developed a robust and simple, PCR-based host-blood transcriptomic signature, RISK6, for multiple applications: identifying individuals at risk of i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b72b4b335a138b78e75f4f968504b069
https://researchonline.lshtm.ac.uk/id/eprint/4656993/1/s41598-020-65043-8.pdf

Tuberculosis.

Autor: Frieden TR (AUTHOR), Sterling TR (AUTHOR), Munsiff SS (AUTHOR), Watt CJ (AUTHOR), Dye C (AUTHOR)

Publikováno v: Lancet. 9/13/2003, Vol. 362 Issue 9387, p887-899. 13p.

Long-term Mortality in HIV-Positive Individuals Virally Suppressed for > 3 Years With Incomplete CD4 Recovery

Autor: Engsig, FN, Zangerle, R, Katsarou, O, Dabis, F, Reiss, P, Gill, J, Porter, K, Sabin, C, Riordan, A, Fatkenheuer, G, Gutierrez, F, Raffi, F, Kirk, O, Mary-Krause, M, Stephan, C, de Olalla, PG, Guest, J, Samji, H, Castagna, A, Monforte, AD, Skaletz-Rorowski, A, Ramos, J, Lapadula, G, Mussini, C, Force, L, Meyer, L, Lampe, F, Boufassa, F, Bucher, HC, De Wit, S, Burkholder, GA, Teira, R, Justice, AC, Sterling, TR, Crane, HM, Gerstoft, J, Grarup, J, May, M, Chene, G, Ingle, SM, Sterne, J, Obel, N

Publikováno v: CLINICAL INFECTIOUS DISEASES
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname

Background. Some human immunodeficiency virus (HIV)-infected individuals initiating combination antiretroviral therapy (cART) with low CD4 counts achieve viral suppression but not CD4 cell recovery. We aimed to identify (1) risk factors for failure t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::d0532aea9b1acbf4d3664904844f6cb8
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=9326

Body mass index and the risk of incident noncommunicable diseases after starting antiretroviral therapy.

Autor: Koethe, JR, Jenkins, CA, Turner, M, Bebawy, S, Shepherd, BE, Wester, CW, Sterling, TR

Publikováno v: HIV Medicine; Jan2015, Vol. 16 Issue 1, p67-72, 6p

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