Zobrazeno 1 - 10
of 18 684
pro vyhledávání: '"Sterling, C"'
Autor:
Safai, Apoorva, Jonaitis, Erin, Langhough, Rebecca E, Buckingham, William R, Johnson, Sterling C., Powell, W. Ryan, Kind, Amy J. H., Bendlin, Barbara B., Tiwari, Pallavi
Neighborhood disadvantage is associated with worse health and cognitive outcomes. Morphological similarity network (MSN) is a promising approach to elucidate cortical network patterns underlying complex cognitive functions. We hypothesized that MSNs
Externí odkaz:
http://arxiv.org/abs/2406.13822
Autor:
Junhao Wen, Zhijian Yang, Ilya M. Nasrallah, Yuhan Cui, Guray Erus, Dhivya Srinivasan, Ahmed Abdulkadir, Elizabeth Mamourian, Gyujoon Hwang, Ashish Singh, Mark Bergman, Jingxuan Bao, Erdem Varol, Zhen Zhou, Aleix Boquet-Pujadas, Jiong Chen, Arthur W. Toga, Andrew J. Saykin, Timothy J. Hohman, Paul M. Thompson, Sylvia Villeneuve, Randy Gollub, Aristeidis Sotiras, Katharina Wittfeld, Hans J. Grabe, Duygu Tosun, Murat Bilgel, Yang An, Daniel S. Marcus, Pamela LaMontagne, Tammie L. Benzinger, Susan R. Heckbert, Thomas R. Austin, Lenore J. Launer, Mark Espeland, Colin L. Masters, Paul Maruff, Jurgen Fripp, Sterling C. Johnson, John C. Morris, Marilyn S. Albert, R. Nick Bryan, Susan M. Resnick, Luigi Ferrucci, Yong Fan, Mohamad Habes, David Wolk, Li Shen, Haochang Shou, Christos Davatzikos
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Alzheimer’s disease (AD) is associated with heterogeneous atrophy patterns. We employed a semi-supervised representation learning technique known as Surreal-GAN, through which we identified two latent dimensional representations of brain a
Externí odkaz:
https://doaj.org/article/56d631e8319148739bce0f8e8b35d005
Autor:
Tomas Vikner, Kevin M. Johnson, Robert V. Cadman, Tobey J. Betthauser, Rachael E. Wilson, Nathaniel Chin, Laura B. Eisenmenger, Sterling C. Johnson, Leonardo A. Rivera-Rivera
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-11 (2024)
Abstract Background Cerebrospinal fluid (CSF) dynamics are increasingly studied in aging and neurological disorders. Models of CSF-mediated waste clearance suggest that altered CSF dynamics could play a role in the accumulation of toxic waste in the
Externí odkaz:
https://doaj.org/article/666e52bf2c404fdfa18dc835eca83698
Autor:
Kitty K. Lui, Abhishek Dave, Kate E. Sprecher, Miranda G. Chappel-Farley, Brady A. Riedner, Margo B. Heston, Chase E. Taylor, Cynthia M. Carlsson, Ozioma C. Okonkwo, Sanjay Asthana, Sterling C. Johnson, Barbara B. Bendlin, Bryce A. Mander, Ruth M. Benca
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-15 (2024)
Abstract Background Obstructive sleep apnea (OSA) increases risk for cognitive decline and Alzheimer’s disease (AD). While the underlying mechanisms remain unclear, hypoxemia during OSA has been implicated in cognitive impairment. OSA during rapid
Externí odkaz:
https://doaj.org/article/0ace0e428a314524b2ba362c438b75ac
Autor:
Yang, Zhijian, Wen, Junhao, Abdulkadir, Ahmed, Cui, Yuhan, Erus, Guray, Mamourian, Elizabeth, Melhem, Randa, Srinivasan, Dhivya, Govindarajan, Sindhuja T., Chen, Jiong, Habes, Mohamad, Masters, Colin L., Maruff, Paul, Fripp, Jurgen, Ferrucci, Luigi, Albert, Marilyn S., Johnson, Sterling C., Morris, John C., LaMontagne, Pamela, Marcus, Daniel S., Benzinger, Tammie L. S., Wolk, David A., Shen, Li, Bao, Jingxuan, Resnick, Susan M., Shou, Haochang, Nasrallah, Ilya M., Davatzikos, Christos
Disease heterogeneity has been a critical challenge for precision diagnosis and treatment, especially in neurologic and neuropsychiatric diseases. Many diseases can display multiple distinct brain phenotypes across individuals, potentially reflecting
Externí odkaz:
http://arxiv.org/abs/2301.10772
Autor:
Du, Lianlian, Koscik, Rebecca Langhough, Betthauser, Tobey J, Johnson, Sterling C., Larget, Bret, Chappell, Rick
Preclinical Alzheimer's disease (AD), the earliest stage in the AD continuum, can last fifteen to twenty years, with cognitive decline trajectories nonlinear and heterogeneous between subjects. Characterizing cognitive decline in the preclinical phas
Externí odkaz:
http://arxiv.org/abs/2211.09915
Autor:
Donghui Yan, Bowen Hu, Burcu F Darst, Shubhabrata Mukherjee, Brian W Kunkle, Yuetiva Deming, Logan Dumitrescu, Yunling Wang, Adam Naj, Amanda Kuzma, Yi Zhao, Hyunseung Kang, Sterling C Johnson, Cruchaga Carlos, Timothy J Hohman, Paul K Crane, Corinne D Engelman, Alzheimer’s Disease Genetics Consortium (ADGC), Qiongshi Lu
Publikováno v:
eLife, Vol 12 (2024)
Rich data from large biobanks, coupled with increasingly accessible association statistics from genome-wide association studies (GWAS), provide great opportunities to dissect the complex relationships among human traits and diseases. We introduce BAD
Externí odkaz:
https://doaj.org/article/70e5d04b97aa44e69655821a17499202
Autor:
Bruno, Davide, Jauregi-Zinkunegi, Ainara, Betthauser, Tobey, Carlsson, Cynthia, Bendlin, Barbara B., Okonkwo, Ozioma, Chin, Nathaniel A., Asthana, Sanjay, Langhough, Rebecca E., Johnson, Sterling C., Mueller, Kimberly D.
Publikováno v:
In Journal of the Neurological Sciences 15 September 2024 464
Autor:
Carol Van Hulle, Selvi Ince, Ozioma C. Okonkwo, Barbara B. Bendlin, Sterling C. Johnson, Cynthia M. Carlsson, Sanjay Asthana, Seth Love, Kaj Blennow, Henrik Zetterberg, J. Scott Miners
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Breakdown of the neurovascular unit is associated with blood-brain barrier (BBB) leakiness contributing to cognitive decline and disease pathology in the early stages of Alzheimer’s disease (AD). Vascular stability depends on angiopoietin-
Externí odkaz:
https://doaj.org/article/e810f28aac8941cab385eb1aa712f3ca
Autor:
Zhijian Yang, Junhao Wen, Ahmed Abdulkadir, Yuhan Cui, Guray Erus, Elizabeth Mamourian, Randa Melhem, Dhivya Srinivasan, Sindhuja T. Govindarajan, Jiong Chen, Mohamad Habes, Colin L. Masters, Paul Maruff, Jurgen Fripp, Luigi Ferrucci, Marilyn S. Albert, Sterling C. Johnson, John C. Morris, Pamela LaMontagne, Daniel S. Marcus, Tammie L. S. Benzinger, David A. Wolk, Li Shen, Jingxuan Bao, Susan M. Resnick, Haochang Shou, Ilya M. Nasrallah, Christos Davatzikos
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Disease heterogeneity has been a critical challenge for precision diagnosis and treatment, especially in neurologic and neuropsychiatric diseases. Many diseases can display multiple distinct brain phenotypes across individuals, potentially r
Externí odkaz:
https://doaj.org/article/e4408877453444c49479a4dba3887d8a