Proteomic analysis of arylamine N -acetyltransferase 1 knockout breast cancer cells: Implications in immune evasion and mitochondrial biogenesis.

Autor: Hong KU; Department of Pharmacology & Toxicology, School of Medicine, University of Louisville, Louisville, KY, USA., Gardner JQ; Department of Pharmacology & Toxicology, School of Medicine, University of Louisville, Louisville, KY, USA., Doll MA; Department of Pharmacology & Toxicology, School of Medicine, University of Louisville, Louisville, KY, USA., Stepp MW; Department of Pharmacology & Toxicology, School of Medicine, University of Louisville, Louisville, KY, USA., Wilkey DW; Department of Medicine, School of Medicine, University of Louisville, Louisville, KY, USA., Benz FW; Department of Pharmacology & Toxicology, School of Medicine, University of Louisville, Louisville, KY, USA., Cai J; Department of Medicine, School of Medicine, University of Louisville, Louisville, KY, USA., Merchant ML; Department of Medicine, School of Medicine, University of Louisville, Louisville, KY, USA., Hein DW; Department of Pharmacology & Toxicology, School of Medicine, University of Louisville, Louisville, KY, USA.

Publikováno v: Toxicology reports [Toxicol Rep] 2022 Jul 19; Vol. 9, pp. 1566-1573. Date of Electronic Publication: 2022 Jul 19 (Print Publication: 2022).

Knockout of human arylamine N-acetyltransferase 1 (NAT1) in MDA-MB-231 breast cancer cells leads to increased reserve capacity, maximum mitochondrial capacity, and glycolytic reserve capacity.

Autor: Carlisle SM; Department of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, Kentucky., Trainor PJ; Division of Cardiovascular Medicine, University of Louisville School of Medicine, Louisville, Kentucky., Doll MA; Department of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, Kentucky., Stepp MW; Department of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, Kentucky., Klinge CM; Department of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, Kentucky., Hein DW; Department of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, Kentucky.

Publikováno v: Molecular carcinogenesis [Mol Carcinog] 2018 Nov; Vol. 57 (11), pp. 1458-1466. Date of Electronic Publication: 2018 Jul 18.

Congenic rats with higher arylamine N-acetyltransferase 2 activity exhibit greater carcinogen-induced mammary tumor susceptibility independent of carcinogen metabolism.

Autor: Stepp MW; Department of Pharmacology and Toxicology, School of Medicine, University of Louisville, Louisville, KY, 40202, USA.; James Graham Brown Cancer Center, University of Louisville, Louisville, KY, 40202, USA., Doll MA; Department of Pharmacology and Toxicology, School of Medicine, University of Louisville, Louisville, KY, 40202, USA.; James Graham Brown Cancer Center, University of Louisville, Louisville, KY, 40202, USA., Samuelson DJ; James Graham Brown Cancer Center, University of Louisville, Louisville, KY, 40202, USA.; Department of Biochemistry & Molecular Genetics, School of Medicine, University of Louisville, Louisville, KY, 40202, USA., Sanders MA; Department of Pathology, University of Louisville Hospital, Louisville, KY, 40202, USA., States JC; Department of Pharmacology and Toxicology, School of Medicine, University of Louisville, Louisville, KY, 40202, USA.; James Graham Brown Cancer Center, University of Louisville, Louisville, KY, 40202, USA., Hein DW; Department of Pharmacology and Toxicology, School of Medicine, University of Louisville, Louisville, KY, 40202, USA. d.hein@louisville.edu.; James Graham Brown Cancer Center, University of Louisville, Louisville, KY, 40202, USA. d.hein@louisville.edu.

Publikováno v: BMC cancer [BMC Cancer] 2017 Mar 31; Vol. 17 (1), pp. 233. Date of Electronic Publication: 2017 Mar 31.

Folate-Dependent Hydrolysis of Acetyl-Coenzyme A by Recombinant Human and Rodent Arylamine N-Acetyltransferases.

Autor: Stepp MW; Department of Pharmacology and Toxicology, James Graham Brown Cancer Center, School of Medicine, University of Louisville., Mamaliga G; Department of Pharmacology and Toxicology, James Graham Brown Cancer Center, School of Medicine, University of Louisville., Doll MA; Department of Pharmacology and Toxicology, James Graham Brown Cancer Center, School of Medicine, University of Louisville., States JC; Department of Pharmacology and Toxicology, James Graham Brown Cancer Center, School of Medicine, University of Louisville., Hein DW; Department of Pharmacology and Toxicology, James Graham Brown Cancer Center, School of Medicine, University of Louisville.

Publikováno v: Biochemistry and biophysics reports [Biochem Biophys Rep] 2015 Sep; Vol. 3, pp. 45-50.

A bioluminescent transgenic mouse model: real-time in vivo imaging of antioxidant EC-SOD gene expression and regulation by interferon gamma.

Autor: Zelko IN; Departments of Medicine and Department of Biochemistry and Molecular Biology, University of Louisville, Louisville, KY 40202, USA. Electronic address: igor.zelko@louisville.edu., Stepp MW, Folz RJ

Publikováno v: Gene [Gene] 2013 Nov 01; Vol. 530 (1), pp. 75-82. Date of Electronic Publication: 2013 Jul 22.