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pro vyhledávání: '"Stephenson Clarke, Joseph Richard"'
Certain genetic mutations reduce the lifetimes of encoded proteins by destabilizing the functional folded form, preventing them from performing their cellular roles. In many cases, significant loss of functionality due to protein destabilization lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______348::96f9a388948ed00eba89436470da30ba
https://eprints.soton.ac.uk/467384/
https://eprints.soton.ac.uk/467384/
Autor:
Chasov, Vitaly, Mirgayazova, Regina, Zmievskaya, Ekaterina, Khadiullina, Raniya, Valiullina, Aygul, Stephenson Clarke, Joseph Richard, Rizvanov, Albert, Baud, Matthias G.J., Bulatov, Emil
The transcription factor p53 is a key tumor suppressor that is inactivated in almost all cancers due to either point mutations in the TP53 gene or overexpression of its negative regulators. The p53 protein is known as the “cellular gatekeeper” fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______348::90d8be1ed1d95156659ce15032c453ae
https://eprints.soton.ac.uk/444147/
https://eprints.soton.ac.uk/444147/