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pro vyhledávání: '"Stephenie Takahashi"'
Autor:
Stephenie Takahashi-Manns, Disha Kumar, Imre Noth, Carley Demchuk, Mary E. Strek, Cathryn Lee, Shruti B. Patel, Justin M. Oldham
BACKGROUND A significant minority of patients with idiopathic pulmonary fibrosis (IPF) display features of autoimmunity without meeting the criteria for overt connective tissue disease. A link between IPF and other immune-mediated processes, such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae1ed2086c606ed2ba11806f0234d9bd
https://europepmc.org/articles/PMC4556122/
https://europepmc.org/articles/PMC4556122/
Autor:
Cara Hrusch, Joshua Casaos, Catherine Bonham, Kelly Blaine, Dana Bryazka, Mohammad Jaffery, Stephenie Takahashi, Imre Noth, Anne Sperling
Publikováno v:
The Journal of Immunology. 194:52.13-52.13
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease causing irreversible lung scarring and loss of pulmonary function. RNA analysis has shown that patients with IPF have reduced ICOS expression in peripheral blood mononuclear cells. We
Publikováno v:
The Journal of Immunology. 192:184.28-184.28
The role of the adaptive immune response in idiopathic pulmonary fibrosis (IPF) has been an area of debate. Several studies have shown that patients with IPF had increased numbers of T cells in their lungs, suggesting that these cells may play a role
Publikováno v:
The Journal of Immunology. 188:54.7-54.7
IPF is an interstitial lung disease that affects over 128,000 people in the U.S., has a yearly mortality of 48,000, and has no effective treatment. Current theories on the etiology of IPF have not focused on the role of the immune system due to the i