Zobrazeno 1 - 10
of 1 352
pro vyhledávání: '"Stephen. T. Holgate"'
Autor:
Phillip D. Monk, Jody L. Brookes, Victoria J. Tear, Toby N. Batten, Clare Newall, Marcin Mankowski, Michael G. Crooks, Dave Singh, Rekha Chaudhuri, Brian Leaker, Kerry Lunn, Sophie Reynolds, Sarah Dudley, Felicity J. Gabbay, Stephen T. Holgate, Ratko Djukanovic, Thomas MA Wilkinson
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract Background Respiratory viral infections are major drivers of chronic obstructive pulmonary disease (COPD) exacerbations. Interferon-β is naturally produced in response to viral infection, limiting replication. This exploratory study aimed t
Externí odkaz:
https://doaj.org/article/0e45758b1a514217839b388bd5252764
Publikováno v:
European Respiratory Review, Vol 15, Iss 101, Pp 172-174 (2006)
We have reported that cysteinyl-leukotrienes (cys-LTs) synergise not only with epidermal growth factor (EGF) but also with platelet-derived growth factor (PDGF) and fibroblast growth factor (FGF) to induce mitogenesis in human bronchial fibroblasts.
Externí odkaz:
https://doaj.org/article/218d40550f994220932f0219e312c84b
The lived experience of immune-mediated noncommunicable diseases in relation to environmental change
Autor:
Stephen T. Holgate
Publikováno v:
Frontiers in Science, Vol 2 (2024)
Externí odkaz:
https://doaj.org/article/b9f3b5ca428544498c964ac338818490
Autor:
Phillip D. Monk, Jody L. Brookes, Victoria J. Tear, Toby N. Batten, Marcin Mankowski, Tatjana Adzic-Vukicevic, Michael G. Crooks, Davinder P.S. Dosanjh, Monica Kraft, Christopher E. Brightling, Felicity J. Gabbay, Stephen T. Holgate, Ratko Djukanovic, Tom M.A. Wilkinson
Publikováno v:
ERJ Open Research, Vol 9, Iss 2 (2023)
Background Despite the availability of vaccines and therapies, patients are being hospitalised with coronavirus disease 2019 (COVID-19). Interferon (IFN)-β is a naturally occurring protein that stimulates host immune responses against most viruses,
Externí odkaz:
https://doaj.org/article/59ef7b2928b0495c936fac3cc3b5d606
Autor:
Nathalie Percie du Sert, Amrita Ahluwalia, Sabina Alam, Marc T Avey, Monya Baker, William J Browne, Alejandra Clark, Innes C Cuthill, Ulrich Dirnagl, Michael Emerson, Paul Garner, Stephen T Holgate, David W Howells, Viki Hurst, Natasha A Karp, Stanley E Lazic, Katie Lidster, Catriona J MacCallum, Malcolm Macleod, Esther J Pearl, Ole H Petersen, Frances Rawle, Penny Reynolds, Kieron Rooney, Emily S Sena, Shai D Silberberg, Thomas Steckler, Hanno Würbel
Publikováno v:
PLoS Biology, Vol 18, Iss 7, p e3000411 (2020)
Improving the reproducibility of biomedical research is a major challenge. Transparent and accurate reporting is vital to this process; it allows readers to assess the reliability of the findings and repeat or build upon the work of other researchers
Externí odkaz:
https://doaj.org/article/0cdc6121568245e7b56bd1cca7b31653
Autor:
Nathalie Percie du Sert, Viki Hurst, Amrita Ahluwalia, Sabina Alam, Marc T Avey, Monya Baker, William J Browne, Alejandra Clark, Innes C Cuthill, Ulrich Dirnagl, Michael Emerson, Paul Garner, Stephen T Holgate, David W Howells, Natasha A Karp, Stanley E Lazic, Katie Lidster, Catriona J MacCallum, Malcolm Macleod, Esther J Pearl, Ole H Petersen, Frances Rawle, Penny Reynolds, Kieron Rooney, Emily S Sena, Shai D Silberberg, Thomas Steckler, Hanno Würbel
Publikováno v:
PLoS Biology, Vol 18, Iss 7, p e3000410 (2020)
Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in 2010 to improve the reporting of animal research. They consist of a checklist of information t
Externí odkaz:
https://doaj.org/article/143566b401ed41fd9517d9c18b875cd9
Autor:
Phillip D. Monk, Jody L. Brookes, Victoria J. Tear, Toby N. Batten, Marcin Mankowski, Tatjana Adzic-Vukicevic, Michael G. Crooks, Davinder P.S. Dosanjh, Monica Kraft, Christopher E. Brightling, Felicity J. Gabbay, Stephen T. Holgate, Ratko Djukanovic, Tom M.A. Wilkinson
Publikováno v:
ERJ Open Research. 9:00605-2022
BackgroundDespite the availability of vaccines and therapies, patients are being hospitalised with coronavirus disease 2019 (COVID-19). Interferon (IFN)-β is a naturally occurring protein that stimulates host immune responses against most viruses, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bed90f6f0203c43d69297ac6381c503f
https://doi.org/10.1183/23120541.00605-2022
https://doi.org/10.1183/23120541.00605-2022
Autor:
Phillip D Monk, Rachael A Evans, Victoria J Tear, Jody L Brookes, Toby Batten, Marcin Mankowski, Ratko Djukanovic, Stephen T Holgate, Chris Brightling, Tom Wilkinson
Publikováno v:
Open Forum Infectious Diseases. 9
Background People with post-COVID conditions can have a wide range of symptoms lasting months and it can affect as many as one in five infected people. Interferon beta (IFN-β) is key in host defence against viruses but can be suppressed by virus or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29b88e17c5f9d11d64c6b705cb220a23
https://doi.org/10.1093/ofid/ofac492.1879
https://doi.org/10.1093/ofid/ofac492.1879
Publikováno v:
Thorax. 77:851-853
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6996f48d6c46887d909e0269c873523
https://doi.org/10.1136/thoraxjnl-2021-218459
https://doi.org/10.1136/thoraxjnl-2021-218459
Autor:
Wiparat Manuyakorn, David E Smart, Antonio Noto, Fabio Bucchieri, Hans Michael Haitchi, Stephen T Holgate, Peter H Howarth, Donna E Davies
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153926 (2016)
Asthma is characterized by periodic episodes of bronchoconstriction and reversible airway obstruction; these symptoms are attributable to a number of factors including increased mass and reactivity of bronchial smooth muscle and extracellular matrix
Externí odkaz:
https://doaj.org/article/e9261446e53c4bd6aad04bf6d35ad142