Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Stephen Y. K. Seah"'
Autor:
Nadine Abraham, Kurt L. Schroeter, Yan Zhu, Jonathan Chan, Natasha Evans, Matthew S. Kimber, Jason Carere, Ting Zhou, Stephen Y. K. Seah
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Deoxynivalenol (DON) is a mycotoxin, produced by filamentous fungi such as Fusarium graminearum, that causes significant yield losses of cereal grain crops worldwide. One of the most promising methods to detoxify this mycotoxin involves its
Externí odkaz:
https://doaj.org/article/2968f6144fc648abb84d2cd16bf87380
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Mycotoxins are toxic secondary metabolites produced by certain genera of fungi including but not limited to Fusarium, Aspergillus, and Penicillium. Their persistence in agricultural commodities poses a significant food safety issue owing to their car
Externí odkaz:
https://doaj.org/article/ba3060be7f73461e8087441ef62accfe
Publikováno v:
Pathogens, Vol 12, Iss 3, p 407 (2023)
Gut alkaline phosphatases (AP) dephosphorylate the lipid moiety of endotoxin and other pathogen-associated-molecular patterns members, thus maintaining gut eubiosis and preventing metabolic endotoxemia. Early weaned pigs experience gut dysbiosis, ent
Externí odkaz:
https://doaj.org/article/ca3d36b31c5e4aaea9cae18194b6dd62
Publikováno v:
Toxins, Vol 14, Iss 7, p 423 (2022)
Patulin is a mycotoxin that primarily contaminate apples and apple products. Whole cell or cell-free extracts of Gluconobacter oxydans ATCC 621 were able to transform patulin to E-ascladiol. Proteins from cell-free extracts were separated by anion ex
Externí odkaz:
https://doaj.org/article/7fa1de41e9e54a53850aaf61b87e158a
Autor:
Kurt L. Schroeter, Nadine Abraham, Nicolas Rolfe, Rebecca Barnshaw, Jaclyn Diamond, Stephen Y. K. Seah
Publikováno v:
J Bacteriol
Actinobacterial MaoC family enoyl coenzyme A (CoA) hydratases catalyze the addition of water across the double bond of CoA esters during steroid side chain catabolism. We determined that heteromeric MaoC type hydratases, exemplified by ChsH1-ChsH2(Mt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c317f25cad5c6608f4f708a31faadaf2
https://pubmed.ncbi.nlm.nih.gov/36000836
https://pubmed.ncbi.nlm.nih.gov/36000836
Autor:
Scott Mazurkewich, Stephen Y K Seah
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164556 (2016)
The 4-hydroxy-4-methyl-2-oxoglutarate (HMG)/4-carboxy-4-hydroxy-2-oxoadipate (CHA) aldolase is the last enzyme of both the gallate and protocatechuate 4,5-cleavage pathways which links aromatic catabolism to central cellular metabolism. The enzyme is
Externí odkaz:
https://doaj.org/article/0d48b4bff5254d2a8a45a23210b123c2
Autor:
Stephanie E. Gilbert, Stephen Y. K. Seah, Alexander J. Stirling, Evan Mallette, Matthew S. Kimber, Megan Conner
Publikováno v:
Biochemistry. 59:4081-4092
A wide variety of steroid metabolites synthesized by eukaryotes are all ultimately catabolized by bacteria; while generally saprophytic, pathogenic Mycobacteria have repurposed these pathways to utilize host intracellular cholesterol pools. Steroid d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd193422f54f028fb138ae044ee3394
https://doi.org/10.1021/acs.biochem.0c00568
https://doi.org/10.1021/acs.biochem.0c00568
Autor:
Stephanie E. Gilbert, Evan Mallette, Matthew S. Kimber, Stephen Y. K. Seah, Kurt L. Schroeter, Rebecca Aggett, Melody A. Vachon
Publikováno v:
Journal of Biological Chemistry. 294:11934-11943
An aldolase from the bile acid-degrading actinobacterium Thermomonospora curvata catalyzes the C-C bond cleavage of an isopropyl-CoA side chain from the D-ring of the steroid metabolite 17-hydroxy-3-oxo-4-pregnene-20-carboxyl-CoA (17-HOPC-CoA). Like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d139c5cabf3df4a0881838a807856ef
https://doi.org/10.1074/jbc.ra119.008889
https://doi.org/10.1074/jbc.ra119.008889
Autor:
Olivier Côté, Mary Ellen Clark, Laurent Viel, Geneviève Labbé, Stephen Y K Seah, Meraj A Khan, David N Douda, Nades Palaniyar, Dorothee Bienzle
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e96217 (2014)
Secretoglobin family 1A member 1 (SCGB 1A1) is a small protein mainly secreted by mucosal epithelial cells of the lungs and uterus. SCGB 1A1, also known as club (Clara) cell secretory protein, represents a major constituent of airway surface fluid. T
Externí odkaz:
https://doaj.org/article/5c0d2fbc6f6041ed884ab2869011124e
Publikováno v:
Proceedings of 1st International Electronic Conference on Toxins.
Deoxynivalenol (DON) is a toxic fungal secondary metabolite produced by Fusarium graminearum which causes Fusarium Head Blight and Pink Ear Rot disease in wheat and corn respectively. DON is a predominant contaminant in cereal grain crops with outbre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d105452b5b683ee22f271773ab84dd25
https://doi.org/10.3390/iect2021-09171
https://doi.org/10.3390/iect2021-09171