Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Stephen W. Lumsdaine"'
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT To successfully induce disease, Candida albicans must effectively evade the host immune system. One mechanism used by C. albicans to achieve this is to mask immunogenic β(1,3)-glucan epitopes within its cell wall under an outer layer of man
Externí odkaz:
https://doaj.org/article/96f3ae7615d74663b8e957ac9dca9926
Autor:
Andrew S Wagner, Stephen W Lumsdaine, Mikayla M Mangrum, Ainsley E King, Trevor J Hancock, Timothy E Sparer, Todd B Reynolds
Publikováno v:
PLoS Genetics, Vol 18, Iss 9, p e1010405 (2022)
In order to successfully induce disease, the fungal pathogen Candida albicans regulates exposure of antigens like the cell wall polysaccharide ß(1,3)-glucan to the host immune system. C. albicans covers (masks) ß(1,3)-glucan with a layer of mannosy
Externí odkaz:
https://doaj.org/article/701a003d398e45fcb66bc35c03808cc2
Autor:
Andrew S Wagner, Trevor J Hancock, Stephen W Lumsdaine, Sarah J Kauffman, Mikayla M Mangrum, Elise K Phillips, Timothy E Sparer, Todd B Reynolds
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009839 (2021)
Masking the immunogenic cell wall epitope ß(1,3)-glucan under an outer layer of mannosylated glycoproteins is an important virulence factor deployed by Candida albicans during infection. Consequently, increased ß(1,3)-glucan exposure (unmasking) re
Externí odkaz:
https://doaj.org/article/cdfab09a60b748168be22f81e6fb3981
Autor:
Mikayla M. Mangrum, Trevor J. Hancock, Elise K. Phillips, Tim E. Sparer, Todd B. Reynolds, Stephen W. Lumsdaine, Sarah Kauffman, Andrew S. Wagner
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 8, p e1009839 (2021)
PLoS Pathogens, Vol 17, Iss 8, p e1009839 (2021)
Masking the immunogenic cell wall epitope ß(1,3)-glucan under an outer layer of mannosylated glycoproteins is an important virulence factor deployed by Candida albicans during infection. Consequently, increased ß(1,3)-glucan exposure (unmasking) re