Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Stephen T. Sawyer"'
Autor:
Divya S. Vinjamur, Kristen J. Wade, Safa F. Mohamad, Jack L. Haar, Stephen T. Sawyer, Joyce A. Lloyd
Publikováno v:
Haematologica, Vol 99, Iss 10 (2014)
The Krüppel-like transcription factors KLF1 and KLF2 are essential for embryonic erythropoiesis. They can partially compensate for each other during mouse development, and coordinately regulate numerous erythroid genes, including the β-like globins
Externí odkaz:
https://doaj.org/article/e0656e8682134a0cac501bac088eda62
Autor:
Jerry L. Spivak, Stephen T. Sawyer, Teresa A. Zimmers, W. David Hankins, Jacalyn H. Pierce, Pamela N. Pharr, Alan N. Schechter, Sandra K. Ruscetti, Donna M. Williams
Publikováno v:
Annals of the New York Academy of Sciences. 718:232-244
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a499c36709931421d34eb64ed93f982
https://doi.org/10.1111/j.1749-6632.1994.tb55722.x
https://doi.org/10.1111/j.1749-6632.1994.tb55722.x
Publikováno v:
Clinical Cancer Research. 12:2232-2238
Purpose: Erythropoietin (EPO) therapy is widely used for the prevention and treatment of anemia resulting from cancer chemotherapy. Native EPO regulates erythropoiesis, at least in part, by protecting erythroid progenitor cells from apoptotic cell de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97a92249f15bde5378b8daa138d529fd
https://doi.org/10.1158/1078-0432.ccr-05-2287
https://doi.org/10.1158/1078-0432.ccr-05-2287
Autor:
Harry V. Wright, Margaret E. McCoy, Kwan-ho Roh, Brian O. Barnstein, Kevin D. Bunting, Mohit Kashyap, Sheila R. Gillespie, Daniel P. Bailey, Veronika Sexl, Meredith N. Mann, Hey Jin Chong, Christopher P. Shelburne, Stephen T. Sawyer, John J. Ryan, Chris S. Lantz, Paria Mirmonsef, L.Andrew Bouton, Sarah M. Jacobs-Helber, Roland P. Piekorz, Carlos Ramírez
Publikováno v:
Blood. 102:1290-1297
Interleukin-3 (IL-3) and stem cell factor (SCF) are important mast cell growth and differentiation factors. Since both cytokines activate the transcription factor signal transducer and activator of transcription 5 (Stat5), a known regulator of prolif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39802adcdfe7f278b05604171e96b102
https://doi.org/10.1182/blood-2002-11-3490
https://doi.org/10.1182/blood-2002-11-3490
Publikováno v:
Blood. 96:2084-2092
Erythropoietin (EPO) allows erythroid precursors to proliferate while protecting them from apoptosis. Treatment of the EPO-dependent HCD57 murine cell line with 70 μmol/L orthovanadate, a tyrosine phosphatase inhibitor, resulted in both increased ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94fb281788d61ad725e51929b34a1007
https://doi.org/10.1182/blood.v96.6.2084
https://doi.org/10.1182/blood.v96.6.2084
Publikováno v:
Blood. 96:933-940
Jun N-terminal kinase (JNK) and p38, members of the mitogen-activated protein kinase family of serine/threonine kinases, are activated as a result of cellular stress but may also play a role in growth factor-induced proliferation and/or survival or d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55a962f1a8b128a76bc944ec01e0b8d6
https://doi.org/10.1182/blood.v96.3.933
https://doi.org/10.1182/blood.v96.3.933
Publikováno v:
Blood. 96:933-940
Jun N-terminal kinase (JNK) and p38, members of the mitogen-activated protein kinase family of serine/threonine kinases, are activated as a result of cellular stress but may also play a role in growth factor-induced proliferation and/or survival or d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d95be97ef77c22b30d4152d6fb174f15
https://doi.org/10.1182/blood.v96.3.933.015k52_933_940
https://doi.org/10.1182/blood.v96.3.933.015k52_933_940
Publikováno v:
Journal of Hematotherapy & Stem Cell Research. 9:21-29
This review summarizes selected recent studies of the intracellular signals that allow erythroid cells to survive and proliferate under the control of erythropoietin (EPO) and alteration in signals that contribute to EPO-independent survival and prol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bb0b12d0af2a794c62fcb4e53082ed4
https://doi.org/10.1089/152581600319586
https://doi.org/10.1089/152581600319586
Autor:
Arun K. Sharma, Taolin Yi, Stephen T. Sawyer, Yazan Alsayed, Amittha Wickrema, Toshio Hirano, Shahab Uddin, Sarfraz Ahmad, Keigo Nishada, Masahiko Hibi, Leonidas C. Platanias, Gerald Krystal, Fei Chen
Publikováno v:
Journal of Biological Chemistry. 274:24469-24474
Several signaling cascades are activated during engagement of the erythropoietin receptor to mediate the biological effects of erythropoietin. The members of the insulin receptor substrate (IRS) family of proteins play a central role in signaling for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e50ab9a3986e002984b1cfc0dc6a7ff9
https://doi.org/10.1074/jbc.274.35.24469
https://doi.org/10.1074/jbc.274.35.24469