Zobrazeno 1 - 10
of 388
pro vyhledávání: '"Stephen T Sonis"'
Autor:
Abigail Pulsipher, Justin R Savage, Thomas P Kennedy, Kavita Gupta, Benjamin G Cuiffo, Stephen T Sonis, Won Yong Lee
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0249343 (2021)
PurposeOral mucositis (OM) is a common, painful side effect of radiation therapy used for the treatment of head and neck cancer (HNC). Activation of the innate immune system upon irradiation has been identified as a key precipitating event of OM. To
Externí odkaz:
https://doaj.org/article/33b50a1c23c6495c8c45a4afa9958b76
Autor:
Peili Chen, Maria Mancini, Stephen T Sonis, Juan Fernandez-Martinez, Jing Liu, Ezra E W Cohen, F Gary Toback
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152995 (2016)
We have characterized a novel 21 amino acid-peptide derived from Antrum Mucosal Protein (AMP)-18 that mediates growth promotion of cultured normal epithelial cells and mitigates radiation-induced oral mucositis in animal models, while suppressing in
Externí odkaz:
https://doaj.org/article/e2de79fd53674e8982effef7c9ac7c73
Autor:
Maria Lynn Mancini, Stephen T Sonis
Publikováno v:
Frontiers in Pharmacology, Vol 5 (2014)
Fibrosis is a common, persistent and potentially debilitating complication of chemotherapy and radiation regimens used for the treatment of cancer. The molecular mechanisms underlying fibrosis have been well studied and reveal overall processes that
Externí odkaz:
https://doaj.org/article/d4d85798e8044af19db4e89d0a76a27a
Autor:
Anna N. Yaroslavsky, Tyler W. Iorizzo, Amy F. Juliano, Ather Adnan, James D. Carroll, Stephen T. Sonis, Christine N. Duncan, Wendy B. London, Nathaniel S. Treister
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Photobiomodulation therapy (PBMT) is recommended for prevention and treatment of oral mucositis, a painful condition that occurs in cancer patients. Intraoral PBMT is limited to treating distal oral mucosa and oropharynx. Extraoral PBMT may
Externí odkaz:
https://doaj.org/article/0ce093fd025d461a94d184db231336ab
Autor:
Stephen T. Sonis, Alessandro Villa
Publikováno v:
Cancers, Vol 16, Iss 1, p 68 (2023)
It has been 24 years since rapamycin (sirolimus) was approved to mitigate solid organ transplant rejection and 16 years since mTOR (mammalian/mechanistic target of rapamycin) inhibitors reached patients as a cancer therapy. While the clinical benefit
Externí odkaz:
https://doaj.org/article/3195a16444ed4d22bf38361b6a955020
Autor:
Alessandro Villa, Stephen T. Sonis
Publikováno v:
Expert Opinion on Investigational Drugs. 32:301-310
Autor:
Carryn M. Anderson, Christopher M. Lee, Deborah Saunders, Amarinthia E. Curtis, Neal E. Dunlap, Chaitali Nangia, Arielle S. Lee, Philip Kovoor, Voichita Bar-Ad, Abhinand V. Pedadda, Jon Holmlund, Matt Downs, Stephen T. Sonis
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 114:416-421
Avasopasem manganese (GC4419), an investigational selective dismutase mimetic radioprotector, reduced duration, incidence, and severity of severe oral mucositis (World Health Organization grade 3-4) in a phase 2b, randomized, double-blind trial of pa
Publikováno v:
Holland‐Frei Cancer Medicine. :1-14
Autor:
Piamkamon Vacharotayangul, Sook-Bin Woo, Alessandro Villa, Muhammad Ali Shazib, Stephen T. Sonis, Fábio de Abreu Alves, Nathaniel S. Treister, Julia de Santana Rodrigues Velho, Herve Y. Sroussi, Nicole R. LeBoeuf, Brittany A. Klein, Glenn J. Hanna
Publikováno v:
Oral Diseases. 28:9-22
Introduction Immunotherapy with immune checkpoint inhibitors (ICIs) has transformed cancer treatment over the past decade, improving survival rates in numerous advanced cancers. Immune-related adverse events (irAEs) are common and can affect any orga
Publikováno v:
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in CancerReferences. 30(10)