Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Stephen T Reece"'
Autor:
Jonathan Mayito, Adrian R Martineau, Divya Tiwari, Lydia Nakiyingi, David P Kateete, Stephen T Reece, Irene Andia Biraro
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0281559 (2023)
BackgroundThe tuberculin skin test is commonly used to diagnose latent tuberculosis infection (LTBI) in resource-limited settings, but its specificity is limited by factors including cross-reactivity with BCG vaccine and environmental mycobacteria. I
Externí odkaz:
https://doaj.org/article/bb0ac2445f5343b3829f93740457ebe6
Autor:
Julia Tornack, Stephen T Reece, Wolfgang M Bauer, Alexis Vogelzang, Silke Bandermann, Ulrike Zedler, Georg Stingl, Stefan H E Kaufmann, Fritz Melchers
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169119 (2017)
An estimated third of the world's population is latently infected with Mycobacterium tuberculosis (Mtb), with no clinical signs of tuberculosis (TB), but lifelong risk of reactivation to active disease. The niches of persisting bacteria during latent
Externí odkaz:
https://doaj.org/article/153fa9f26ac140558869436ab818e062
Autor:
Martin Gengenbacher, Maria A. Duque-Correa, Peggy Kaiser, Stefanie Schuerer, Doris Lazar, Ulrike Zedler, Stephen T. Reece, Amit Nayyar, Stewart T. Cole, Vadim Makarov, Clifton E. Barry III, Véronique Dartois, Stefan H. E. Kaufmann
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract During active TB in humans a spectrum of pulmonary granulomas with central necrosis and hypoxia exists. BALB/c mice, predominantly used in TB drug development, do not reproduce this complex pathology thereby inaccurately predicting clinical
Externí odkaz:
https://doaj.org/article/653956e7764245f0bc27af8e6d730cfa
Publikováno v:
Clinical Immunology ISBN: 9780702081651
Intracellular bacteria use multiple strategies to enter and persist in host cells. In doing so they must survive a plethora of host defense strategies that straddle innate and adaptive immune mechanisms. Intriguingly, it is the combination of intrace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9208788c3f428bdbe7c4c3eb9f2ad87f
https://doi.org/10.1016/b978-0-7020-8165-1.00026-5
https://doi.org/10.1016/b978-0-7020-8165-1.00026-5
Autor:
Mailis Maes, Zoe A. Dyson, Sarah E. Smith, David A. Goulding, Catherine Ludden, Stephen Baker, Paul Kellam, Stephen T. Reece, Gordon Dougan, Josefin Bartholdson Scott
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/419c66670fae4e049978ccf258772468
Autor:
Sally Forrest, Julie Demaret, Tenagnework Abozen, Begna Tulu, Jonathan Mayito, Metasebia Tegegn, Stephen T Reece, Abraham Aseffa, Emawayish A. Tirfie, Hana Manwandu, Dawit Tayachew, Denise M. O'Sullivan, Adrian R. Martineau, Kathryn A. Harris, Aboma Zewude, Gobena Ameni, Martin Vordermeier, Jim F. Huggett, Gerwyn M. Jones, Taye Tolera Balcha, Stefan Berg, Mulugeta Belay, Aneesh Chandran, Markos Abebe, Sidra Younis, Vlad Nikolayevskyy, Henny M. Martineau, Mahdad Noursadeghi, David A. Jolliffe
Publikováno v:
The Lancet. Microbe
Summary Background Haematopoietic stem cells expressing the CD34 surface marker have been posited as a niche for Mycobacterium tuberculosis complex bacilli during latent tuberculosis infection. Our aim was to determine whether M tuberculosis complex
Autor:
Stephen T. Reece, Adrian R. Martineau, Irene Andia, Mulugeta Belay, Jonathan Mayito, David A. Jolliffe, David P. Kateete
Publikováno v:
The Journal of Infectious Diseases
Latent tuberculosis has been recognized for over a century, but discovery of new niches, where Mycobacterium tuberculosis resides, continues. We evaluated literature on M.tuberculosis locations during latency, highlighting that mesenchymal and hemato
Publikováno v:
AAS Open Research, Vol 3 (2020)
Background: Tuberculin skin test and interferon gamma release assay (IGRA) show limitations in diagnosing latent tuberculosis infection (LTBI) and poorly predict progression to active tuberculosis. This study will explore detection of Mycobacterium t
Autor:
Henny M. Martineau, Martin Vordermeier, Adrian R. Martineau, Julie Demaret, Sidra Younis, Tenagne Abozen, David A. Jolliffe, Kathryn A. Harris, Vlad Nikolayevskyy, Denise M. O'Sullivan, Stefan Berg, Sally Forrest, Dawit Tayachew, Jonathan Mayito, Mahdad Noursadeghi, Gobena Ameni, Markos Abebe, Taye Tolera Balcha, Mulugeta Belay, Abraham Aseffa, Emawayish A. Tirfie, Aboma Zewude, Stephen T Reece, Begna Tulu, Metasebia Tegegn, Jim F. Huggett, Gerwyn M. Jones, Aneesh Chandran, Hana Manwandu
Publikováno v:
SSRN Electronic Journal.
Background: Haematopoietic stem cells expressing the CD34 surface marker have been posited as a niche for M. tuberculosis complex (MTBC) bacilli during latent tuberculosis infection (LTBI). Methods: We conducted a cross-sectional study in Ethiopia to
Autor:
Anca Dorhoi, Carolina Perdomo, Dagmar Oberbeck-Mueller, Ulrike Zedler, Karin Hahnke, Stefan H. E. Kaufmann, Laura Lozza, Alexis Vogelzang, Stephen T. Reece
Publikováno v:
Infection and Immunity
The neonatal Fc receptor (FcRn) extends the systemic half-life of IgG antibodies by chaperoning bound Fc away from lysosomal degradation inside stromal and hematopoietic cells. FcRn also transports IgG across mucosal barriers into the lumen, and yet