Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Stephen Sung Yong Cho"'
Autor:
John J. Osborne, Charles A. Frolik, Charles Willis Lugar, Andrew L. Glasebrook, Jeffrey Alan Dodge, David Lynn Phillips, Stephen Sung Yong Cho
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:993-996
Glucuronide conjugates 1 and 2, the major metabolites of raloxifene, have been prepared and their molecular interactions with the estrogen receptor determined.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d168db0cbda004518c96680971a0d5e
https://doi.org/10.1016/s0960-894x(97)00142-x
https://doi.org/10.1016/s0960-894x(97)00142-x
Autor:
Andrew L. Glasebrook, Larry A. Spangle, Lorri L. Short, Stephen Sung Yong Cho, David Lynn Phillips, Masahiko Sato, Jeffrey Alan Dodge, John J. Osborne, Charles A. Frolik, Henry Uhlman Bryant, Na N. Yang, Martin Michael John, Charles Willis Lugar
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 61:97-106
Raloxifene (LY139481 HCl) is a selective estrogen receptor modulator (SERM) which blocks the effects of estrogen on some tissues, such as the breast and uterus, while mimicking estrogen in other tissues, such as bone. To study the origins of this uni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5ae701cbd776f8dd0570da840ae9d1c
https://doi.org/10.1016/s0960-0760(97)00008-3
https://doi.org/10.1016/s0960-0760(97)00008-3
Autor:
Andrew L. Glasebrook, Lorri L. Short, Timothy Alan Grese, Ellen R. Rowley, Stephen Sung Yong Cho, D. Lynn Phillips, Magee David Edward, Harlan W. Cole, Henry Uhlman Bryant
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:201-206
A series of 2-alkyl and 2-cycloalkyl raloxifene analogs have been prepared and evaluated in both in vitro and in vivo models of estrogen/antiestrogen activity. In particular, the 2-cyclohexyl analogs show promise as potent selective estrogen-receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4219f5508c1394d0226d3d8c3a2e82a
https://doi.org/10.1016/0960-894x(95)00575-e
https://doi.org/10.1016/0960-894x(95)00575-e