Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Stephen Schmidt"'
Autor:
Kyle Mitchell, Stephen Schmidt, Miroslav Pajic, Afsana Chowdhury, Qitong Gao, Warren Grill, Hui-Jie Lee, Jeffrey Cooney, Jennifer Peters, Dennis Turner
Publikováno v:
Brain Stimulation, Vol 16, Iss 1, Pp 224- (2023)
Externí odkaz:
https://doaj.org/article/16fcbd4fa9264bc29ab0fec3f9d6f66e
Publikováno v:
Brain Stimulation, Vol 16, Iss 1, Pp 223-224 (2023)
Externí odkaz:
https://doaj.org/article/3c34484e93754f20a499785fce3e144e
Publikováno v:
Brain Stimulation, Vol 14, Iss 1, Pp 80-87 (2021)
Background: Transcranial electrical stimulation at an appropriate dose may demonstrate intracranial effects, including neuronal stimulation and cerebral blood flow responses. Objective: We performed in vivo experiments on mouse cortex using transcran
Externí odkaz:
https://doaj.org/article/fea66b5b0e6440d7b7422f5cd26d8206
Autor:
Lori S. Friedman, Anwesha Dey, Donald S. Kirkpatrick, Steven T. Staben, Shiva Malek, Alan G. Olivero, Timothy P. Heffron, Laurent Salphati, Gail D. Lewis Phillips, Emile G. Plise, Jonathan Cheong, Jeffrey J. Wallin, Jane Guan, Nicholas Endres, Stephen Schmidt, Eric Stawiski, William F. Forrest, Lilian Phu, Rebecca Hong, Michelle A. Nannini, Deepak Sampath, Mark Merchant, Jason Oeh, Marc Hafner, Emily J. Hanan, Kyle A. Edgar, Kyung W. Song
RTK activity plays a key role in regulating p110a degradation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c3f61f91c6eba4539d57e9ffe438944
https://doi.org/10.1158/2159-8290.22540279
https://doi.org/10.1158/2159-8290.22540279
Autor:
Shiva Malek, Peter K. Jackson, Jason Halladay, Karen Williams, Lewis Gazzard, Gary Cain, Sharon Yee, Diana Jakubiak, Kenton Wong, Judi Ramiscal, Kaska Kowanetz, Jonathan Choi, Yang Xiao, Stephen Schmidt, Marie Evangelista, Tom O'Brien, Michael Flagella, Ivana Yen, Jennifer Epler, Elizabeth Blackwood
GNE-900 potentiates the cytotoxicity of gemcitabine in HCT-116 isogenic variants, irrespective of NHEJ competence.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9176be3998d918ce16a28d9c74b13868
https://doi.org/10.1158/1535-7163.22499412.v1
https://doi.org/10.1158/1535-7163.22499412.v1
Autor:
Shiva Malek, Peter K. Jackson, Jason Halladay, Karen Williams, Lewis Gazzard, Gary Cain, Sharon Yee, Diana Jakubiak, Kenton Wong, Judi Ramiscal, Kaska Kowanetz, Jonathan Choi, Yang Xiao, Stephen Schmidt, Marie Evangelista, Tom O'Brien, Michael Flagella, Ivana Yen, Jennifer Epler, Elizabeth Blackwood
Kinase selectivity profile evaluated at 100 nM GNE-900
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44ea7282ccbed01f459a1dbd7566b476
https://doi.org/10.1158/1535-7163.22499427.v1
https://doi.org/10.1158/1535-7163.22499427.v1
Autor:
Lori S. Friedman, Anwesha Dey, Donald S. Kirkpatrick, Steven T. Staben, Shiva Malek, Alan G. Olivero, Timothy P. Heffron, Laurent Salphati, Gail D. Lewis Phillips, Emile G. Plise, Jonathan Cheong, Jeffrey J. Wallin, Jane Guan, Nicholas Endres, Stephen Schmidt, Eric Stawiski, William F. Forrest, Lilian Phu, Rebecca Hong, Michelle A. Nannini, Deepak Sampath, Mark Merchant, Jason Oeh, Marc Hafner, Emily J. Hanan, Kyle A. Edgar, Kyung W. Song
PIK3CA is one of the most frequently mutated oncogenes; the p110a protein it encodes plays a central role in tumor cell proliferation. Small-molecule inhibitors targeting the PI3K p110a catalytic subunit have entered clinical trials, with early-phase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd67c192262a4b6f3e1d058d9266830
https://doi.org/10.1158/2159-8290.c.6549343
https://doi.org/10.1158/2159-8290.c.6549343
Autor:
Shiva Malek, Peter K. Jackson, Jason Halladay, Karen Williams, Lewis Gazzard, Gary Cain, Sharon Yee, Diana Jakubiak, Kenton Wong, Judi Ramiscal, Kaska Kowanetz, Jonathan Choi, Yang Xiao, Stephen Schmidt, Marie Evangelista, Tom O'Brien, Michael Flagella, Ivana Yen, Jennifer Epler, Elizabeth Blackwood
Pharmacokinetics of GNE-900 in female CD-1 mice or male Sprague-Dawley rats.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a76a80f3a8c9336cf930119821d57f6
https://doi.org/10.1158/1535-7163.22499406.v1
https://doi.org/10.1158/1535-7163.22499406.v1
Autor:
Shiva Malek, Peter K. Jackson, Jason Halladay, Karen Williams, Lewis Gazzard, Gary Cain, Sharon Yee, Diana Jakubiak, Kenton Wong, Judi Ramiscal, Kaska Kowanetz, Jonathan Choi, Yang Xiao, Stephen Schmidt, Marie Evangelista, Tom O'Brien, Michael Flagella, Ivana Yen, Jennifer Epler, Elizabeth Blackwood
Representative data from a cell-based checkpoint abrogation assay.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd48cd98df355fa624c7886bad67cd3
https://doi.org/10.1158/1535-7163.22499421.v1
https://doi.org/10.1158/1535-7163.22499421.v1
Autor:
Shiva Malek, Peter K. Jackson, Jason Halladay, Karen Williams, Lewis Gazzard, Gary Cain, Sharon Yee, Diana Jakubiak, Kenton Wong, Judi Ramiscal, Kaska Kowanetz, Jonathan Choi, Yang Xiao, Stephen Schmidt, Marie Evangelista, Tom O'Brien, Michael Flagella, Ivana Yen, Jennifer Epler, Elizabeth Blackwood
GNE-900 can potentiate the cytotoxicity of gemcitabine, SN-38 and pemetrexed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::966f95c36f92f3a753df6962185ea963
https://doi.org/10.1158/1535-7163.22499418.v1
https://doi.org/10.1158/1535-7163.22499418.v1