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pro vyhledávání: '"Stephen Sarria"'
Autor:
Carlos Castillo‐Saldarriaga, Christine N. S. Santos, Stephen Sarria, Parayil K. Ajikumar, Ralf Takors
Publikováno v:
Microbial Biotechnology, Vol 17, Iss 11, Pp n/a-n/a (2024)
ABSTRACT Yeast extract (YE) is a complex nutritional source associated with high performance on microbial production processes. However, its inherent compositional variability challenges its scalability. While prior efforts have focused on growth‐a
Externí odkaz:
https://doaj.org/article/388e1bbcf1754c809bb68f94e409f427
Autor:
Vikas Patil, Christine Nicole S. Santos, Stephen Sarria, Parayil Kumaran Ajikumar, Ralf Takors
Publikováno v:
Biotechnology and bioengineeringREFERENCES. 118(3)
Amorpha-4,11-diene (AMD4,11) is a precursor to artemisinin, a potent antimalarial drug that is traditionally extracted from the shrubs of Artemisia annua. Despite significant prior efforts to produce artemisinin and its precursors through biotechnolo
Publikováno v:
ACS Synthetic Biology. 7:1179-1187
Medium-chain fatty acids (MCFAs) are key intermediates in the synthesis of medium-chain chemicals including α-olefins and dicarboxylic acids. In bacteria, microbial production of MCFAs is limited by the activity and product profile of acyl-ACP thioe
Publikováno v:
ACS Synthetic Biology. 4:1295-1307
Monoterpene indole alkaloids (MIAs) have important therapeutic value, including as anticancer and antimalarial agents. Because of their chemical complexity, therapeutic MIAs, or advanced intermediates thereof, are often isolated from the native plant
Publikováno v:
Nature biotechnology. 35(12)
Linear, medium-chain (C8-C12) hydrocarbons are important components of fuels as well as commodity and specialty chemicals. As industrial microbes do not contain pathways to produce medium-chain chemicals, approaches such as overexpression of endogeno
Publikováno v:
ACS Synthetic Biology. 3:466-475
The volumetric heating values of today's biofuels are too low to power energy-intensive aircraft, rockets, and missiles. Recently, pinene dimers were shown to have a volumetric heating value similar to that of the tactical fuel JP-10. To provide a su