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pro vyhledávání: '"Stephen S. Rothman"'
Autor:
Stephen S. Rothman
Publikováno v:
The FASEB Journal. 19:1383-1388
The simple fact that there are normal concentrations of various proteins and peptides in blood has broad and surprising implications for how these molecules are released into and removed from the bloodstream by the cells of the body. If, as widely ac
Publikováno v:
Journal of Microscopy. 204:69-86
We describe the preparation of a biological tissue for imaging in a transmission soft X-ray microscope. Sections of exocrine pancreas embedded in glycol methacrylate polymer, an embedding medium widely used in visible light and electron microscopy, w
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 276:E223-E232
The exocrine pancreas and certain salivary glands of mammals secrete a variety of enzymes into the gastrointestinal tract, where they digest food. The same glands also release these enzymes into the bloodstream. This latter process has commonly been
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1293:63-71
As part of a continuing effort to better understand the mechanisms of protein secretion, we compared the mass of pancreatic digestive enzymes, in resting and stimulated states, both in secretion and in the zymogen granule to determine whether their s
Autor:
Siegfried Glenzer, James Hawreliak, Stephen S. Rothman, S. J. Rose, David J. Chapman, Damian Swift, David Braun, Gilbert Collins, Andrea Kritcher
Publikováno v:
AIP Conference Proceedings.
The unprecedented laser capabilities of the National Ignition Facility (NIF) make it possible for the first time to countenance laboratory-scale experiments in which gigabar pressures can be applied to a reasonable volume of material, and sustained l
Publikováno v:
Journal of Microscopy. 168:101-110
SUMMARY The manufacture, construction and performance of a special specimen holder for biological samples suspended in aqueous solution is described. The holder was designed for use in a scanning transmission X-ray microscope. Using it, we have succe
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes. 1071:159-173
After many years of controversy, it is now clear that at least some cells and tissues that secrete more than one product can vary the composition of the secreted mixture as the result of the differential transport of various substances out of the cel
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1074:85-94
The optical density of suspensions of the digestive enzyme-containing zymogen granule, a roughly spherical 1 μm diameter membrane-enclosed subcellular structure isolated from the exocrine pancreas of mammals, is reduced greatly when they are suspend
Autor:
Erik H. Anderson, Eshang Tang, Janos Kirz, Sid Hellman, Menno Oversluizen, Stephen S. Rothman, Dieter P. Kern, I. McNulty, David Attwood, Mark L. Rivers, S. Lindaas, D. Shu, Chris Jacobsen, Kaarin Goncz, Harald Ade, Phil Batson, Christopher Buckley, Harvey Rarback
Publikováno v:
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 291:54-59
The scanning transmission soft X-ray microscope (STXM) that has been under development at the National Synchrotron Light Source [H. Rarback et al., Rev. Sci. Instr. 59 (1988) 52] has been substantially ungraded for operation with the X1 undulator [C.
Autor:
F. Camilo, N. Iskander, Sid Hellman, I. McNulty, R. DiGennaro, Samuel Krinsky, Menno Oversluizen, Harvey Rarback, Janos Kirz, Chris Jacobsen, D. Shu, Christopher Buckley, M. Sharnoff, S. Lindaas, Malcolm R. Howells, David Sayre, Stephen S. Rothman, Harald Ade
Publikováno v:
Journal of X-Ray Science and Technology. 2:274-296
An undulator-based beamline was built and commissioned at the National Synchrotron Light Source to provide tunable coherent radiation in the 200–800 eV range. The low emittance of the storage ring means that the undulator source has high brightness