Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Stephen S. Massett"'
Autor:
Joel M. Hawkins, Lulin Wei, Dennis E. Bourassa, Peter Robert Rose, Jeffery W. Raggon, A. Morgan Stewart, Heather N. Frost, James E. Phillips, Jennifer Lea Rutherford, Michael J. Castaldi, Barbara J. Sitter, Stephen S. Massett, Phillip J. Johnson, Michael G. Vetelino, Thomas Andrew Brandt, David H. Brown Ripin, Karin Neumann
Publikováno v:
Organic Process Research & Development. 9:440-450
The synthesis of the anti-cancer compound 2-methoxy-N-(3-{4-[3-methyl-4-(6-methyl-pyridin-3-yloxy)phenylamino]quinazolin-6-yl}-E-allyl)acetamide (CP-724,714) (1) on multikilogram scale using several different synthetic routes is described. Applicatio
Autor:
Constantine Sklavounos, Peter Robert Rose, Braish Tamim F, Stephen S. Massett, Michael Butters, Timothy Norris, Dinos Santafianos, Devries Keith Michael, Joel M. Hawkins
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :1615-1622
Trovafloxacin, a novel broad spectrum antibacterial, contains the unusual (1α,5α,6α)-3-azabicyclo[3.1.0]hexane ring system. The prototype of the industrial synthesis of this ring system and possible mechanistic pathways to exclusive formation of t
Autor:
Thomas Staigers, Susan L. Pezzullo, Chiu Charles K, Ralph Breitenbach, Stephen S. Massett, Morgan Meltz, C.William Murtiashaw
Publikováno v:
Tetrahedron: Asymmetry. 7:435-442
Chiral 3-methyl-heptanoic acid is readily accessible by functional group manipulation of optically active citronellol. In principle, this approach is general and could be applied to the synthesis of chiral 3-methyl-alkanoic acids seven carbon atoms i
Autor:
Don Bryant, Robert W. Dugger, Jane L. Ralbovsky, Joe R. Selvidio, Stephen S. Massett, Jane Commander, Sage Nancy Anne
Publikováno v:
ChemInform. 24
A new synthesis of nor-C-statine is described. Benzylation of a malate dianion, differentiation of the two carboxylates and a Hofmann degradation of one of the carboxylates constitute the key steps of the synthesis.
Autor:
Jane L. Ralbovsky, Joe R. Selvidio, Robert W. Dugger, Jane Commander, Sage Nancy Anne, Stephen S. Massett, Don Bryant
Publikováno v:
Tetrahedron Letters. 33:6763-6766
A new synthesis of nor-C-statine is described. Benzylation of a malate dianion, differentiation of the two carboxylates and a Hofmann degradation of one of the carboxylates constitute the key steps of the synthesis.
Autor:
Braish Tamim F, Joel M. Hawkins, Peter Robert Rose, Constantine Sklavounos, Timothy Norris, Devries Keith Michael, Dinos Santafianos, Stephen S. Massett, Michael Butters
Publikováno v:
ChemInform. 31
Trovafloxacin, a novel broad spectrum antibacterial, contains the unusual (1α,5α,6α)-3-azabicyclo[3.1.0]hexane ring system. The prototype of the industrial synthesis of this ring system and possible mechanistic pathways to exclusive formation of t
Autor:
Stephen S. Massett, Susumu Nakanishi
Publikováno v:
Organic Preparations and Procedures International. 12:219-223