Zobrazeno 1 - 10
of 283
pro vyhledávání: '"Stephen S Whitehead"'
Autor:
Anbalagan Anantharaj, Tanvi Agrawal, Pooja Kumari Shashi, Alok Tripathi, Parveen Kumar, Imran Khan, Madhu Pareek, Balwant Singh, Chitra Pattabiraman, Saurabh Kumar, Rajesh Pandey, Anmol Chandele, Rakesh Lodha, Stephen S. Whitehead, Guruprasad R. Medigeshi
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-15 (2023)
Abstract Background India is hyperendemic to dengue and over 50% of adults are seropositive. There is limited information on the association between neutralizing antibody profiles from prior exposure and viral RNA levels during subsequent infection.
Externí odkaz:
https://doaj.org/article/e27f036701814e108f9e0aa268fe6a38
Autor:
Camila D. Odio, Kelsey E. Lowman, Melissa Law, Rosemary A. Aogo, Sally Hunsberger, Brad J. Wood, Michael Kassin, Elliot Levy, Viviane Callier, Saba Firdous, Chloe M. Hasund, Charlie Voirin, Robbie Kattappuram, Christina Yek, Jessica Manning, Anna Durbin, Stephen S. Whitehead, Leah C. Katzelnick
Publikováno v:
BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Background The four co-circulating and immunologically interactive dengue virus serotypes (DENV1-4) pose a unique challenge to vaccine design because sub-protective immunity can increase the risk of severe dengue disease. Existing dengue vac
Externí odkaz:
https://doaj.org/article/07ef6a24744f4c7f8a2c427b11a8f22b
Autor:
John P. Hanley, Huy A. Tu, Julie A. Dragon, Dorothy M. Dickson, Roxana del Rio-Guerra, Scott W. Tighe, Korin M. Eckstrom, Nicholas Selig, Samuel V. Scarpino, Stephen S. Whitehead, Anna P. Durbin, Kristen K. Pierce, Beth D. Kirkpatrick, Donna M. Rizzo, Seth Frietze, Sean A. Diehl
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Dengue virus causes a range of inflammatory pathology but understanding critical phases of the infection during human infection has been challenging. Here the author’s present immunotranscriptomic changes during the acute and clearance phases of a
Externí odkaz:
https://doaj.org/article/1fe0cf67b1b04e8abd252adbf26c1917
Autor:
Ruixue Hou, Lewis E. Tomalin, Jessica Pintado Silva, Seunghee Kim-Schulze, Stephen S. Whitehead, Ana Fernandez-Sesma, Anna P. Durbin, Mayte Suárez-Fariñas
Publikováno v:
JCI Insight, Vol 7, Iss 11 (2022)
Understanding the immune response to dengue virus (DENV) is essential for developing a dengue vaccine that is protective against all 4 DENV serotypes. We evaluated the immune response after vaccination (live attenuated tetravalent dengue vaccine TV00
Externí odkaz:
https://doaj.org/article/9dbf6f21220f45619c849fe8e631f7de
Autor:
Laura K. Aisenberg, Kimberly E. Rousseau, Katherine Cascino, Guido Massaccesi, William H. Aisenberg, Wensheng Luo, Kar Muthumani, David B. Weiner, Stephen S. Whitehead, Michael A. Chattergoon, Anna P. Durbin, Andrea L. Cox
Publikováno v:
JCI Insight, Vol 7, Iss 12 (2022)
The Aedes aegypti mosquito transmits both dengue virus (DENV) and Zika virus (ZIKV) . Individuals in endemic areas are at risk for infection with both viruses, as well as for repeated DENV infection. In the presence of anti-DENV antibodies, outcomes
Externí odkaz:
https://doaj.org/article/b518d8789686457aafe5b023c2ac3a9d
Autor:
Angkana T Huang, Henrik Salje, Ana Coello Escoto, Nayeem Chowdhury, Christian Chávez, Bernardo Garcia-Carreras, Wiriya Rutvisuttinunt, Irina Maljkovic Berry, Gregory D Gromowski, Lin Wang, Chonticha Klungthong, Butsaya Thaisomboonsuk, Ananda Nisalak, Luke M Trimmer-Smith, Isabel Rodriguez-Barraquer, Damon W Ellison, Anthony R Jones, Stefan Fernandez, Stephen J Thomas, Derek J Smith, Richard Jarman, Stephen S Whitehead, Derek A T Cummings, Leah C Katzelnick
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010500 (2022)
Neutralizing antibodies are important correlates of protection against dengue. Yet, determinants of variation in neutralization across strains within the four dengue virus serotypes (DENV1-4) is imperfectly understood. Studies focus on structural DEN
Externí odkaz:
https://doaj.org/article/848bfe09bb3643b49eb637eb2583fe90
Autor:
Usha K. Nivarthi, Huy A. Tu, Matthew J. Delacruz, Jesica Swanstrom, Bhumi Patel, Anna P. Durbin, Stephen S. Whitehead, Kristen K. Pierce, Beth D. Kirkpatrick, Ralph S. Baric, Ngan Nguyen, Daniel E. Emerling, Aravinda M. de Silva, Sean A. Diehl
Publikováno v:
EBioMedicine, Vol 41, Iss , Pp 465-478 (2019)
Background: Acute viral infections induce a rapid and transient increase in antibody-secreting plasmablasts. At convalescence, memory B cells (MBC) and long-lived plasma cells (LLPC) are responsible for long-term humoral immunity. Following an acute
Externí odkaz:
https://doaj.org/article/45231aa80399430b9d9c3fb01e76024a
Autor:
Konstantin A. Tsetsarkin, Olga A. Maximova, Guangping Liu, Heather Kenney, Natalia Teterina, Marshall E. Bloom, Jeffrey M. Grabowski, Luwanika Mlera, Bianca M. Nagata, Ian Moore, Craig Martens, Emerito Amaro-Carambot, Elaine W. Lamirande, Stephen S. Whitehead, Alexander G. Pletnev
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
The mechanisms of ZIKV persistence in the male reproductive tract (MRT) are poorly understood. Here, Tsetsarkin et al. applied microRNA-targeting approach to trace routes of ZIKV dissemination in the testis and epididymis and to generate immunogenic
Externí odkaz:
https://doaj.org/article/ee7bfcbe055342979d1b86ee82672e3a
Autor:
David R. Martinez, Boyd Yount, Usha Nivarthi, Jennifer E. Munt, Matthew J. Delacruz, Stephen S. Whitehead, Anna P. Durbin, Aravinda M. de Silva, Ralph S. Baric
Publikováno v:
Cell Reports, Vol 33, Iss 1, Pp 108226- (2020)
Summary: Dengue virus (DENV) infects an estimated 390 million people each year worldwide. As tetravalent DENV vaccines have variable efficacy against DENV serotype 2 (DENV2), we evaluated the role of genetic diversity within the pre-membrane (prM) an
Externí odkaz:
https://doaj.org/article/f08922d8a3db45c9993b10a150269f7f
Autor:
Rebecca C Christofferson, Daniel M Parker, Hans J Overgaard, Jeffrey Hii, Gregor Devine, Bruce A Wilcox, Vu Sinh Nam, Sazaly Abubakar, Sebastien Boyer, Kobporn Boonnak, Stephen S Whitehead, Rekol Huy, Leang Rithea, Tho Sochantha, Thomas E Wellems, Jesus G Valenzuela, Jessica E Manning
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 7, p e0008302 (2020)
Externí odkaz:
https://doaj.org/article/493fc08ebfe1439f802a802e4feb25d7