Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Stephen Rumbelow"'
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 364 (2022)
Absorption studies on oral drugs can be difficult due to the challenge of replicating the complex structure and environment of the GI tract. Drug absorption studies can be conducted using in vivo and ex vivo animal tissue or animal-free techniques. T
Externí odkaz:
https://doaj.org/article/a61b31d289d2483f802fd96afb96e5df
Autor:
Steve Russell, Wenqiang Liu, Aadithya Kannan, Tamanna Shobha, Kyle Ritchie, Anthony Tomlinson, Miguel Saggu, Stephen Rumbelow, Jamie Giddings, Rosalynn Taing, Kathrin Gregoritza, Nidhi Doshi, Sandeep Yadav, Victor Nicoulin, Jeff Chu, Si Kai Cai, Lin Luis
Publikováno v:
Pharmaceutical research. 38(9)
To evaluate a modified high purity polysorbate 20 (RO HP PS20)—with lower levels of stearate, palmitate and myristate esters than the non-modified HP PS20—as a surfactant in biopharmaceutical drug products (DP). RO HP PS20 was designed to provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a21df0590584752abfffc3de701c783
https://pubmed.ncbi.nlm.nih.gov/34495486
https://pubmed.ncbi.nlm.nih.gov/34495486
Autor:
Stephen Rumbelow, Kevin Penfield
Publikováno v:
Rapid communications in mass spectrometry : RCMREFERENCES. 34
Polysorbates are used in a variety of applications over a wide range of markets. Simple in concept, these products are complex in actual composition. Mass spectrometry and related techniques have been effectively used to characterize these products,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3375518a6c3a2ae6bd0bae983d6db4f7
https://pubmed.ncbi.nlm.nih.gov/31943438
https://pubmed.ncbi.nlm.nih.gov/31943438
Autor:
Cristina Russo, Neil Brickelbank, Catherine J. Duckett, Steve Mellor, Malcolm R. Clench, Stephen Rumbelow
The combination of microspotting of analytical and internal standards, matrix sublimation, and recently developed software for quantitative mass spectrometry imaging has been used to develop a high-resolution method for the determination of terbinafi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08adf628bcc72a912ed3398321825abb
https://shura.shu.ac.uk/22212/1/Clench-QuantitativeInvestigationOfTerbinafine(AM).pdf
https://shura.shu.ac.uk/22212/1/Clench-QuantitativeInvestigationOfTerbinafine(AM).pdf
Publikováno v:
Drug Metabolism and Pharmacokinetics. 33:S42
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bce541965796ac38be6e6961f58b065
https://doi.org/10.1016/j.dmpk.2017.11.148
https://doi.org/10.1016/j.dmpk.2017.11.148
Publikováno v:
Journal of Chromatography A. 1052:161-166
Alcohol ethoxylates (AEOs) that contain a wide distribution of oligomers pose a challenge for ultraviolet (UV) absorbance detection due to the fact that the AEOs absorb strongly only in the range of commercial UV detectors between 190 and 200 nm. Mos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::724085cec7f0ebb85f65c6102493326d
https://doi.org/10.1016/j.chroma.2004.08.106
https://doi.org/10.1016/j.chroma.2004.08.106
Publikováno v:
Journal of chromatography. A. 1043(2)
Supercritical fluid chromatography (SFC) was used for the analysis of ethoxylated and propoxylated surfactants. Samples were derivatized to phenylated silyl ethers with a disilazane–chlorosilane mixture. Addition of a phenyl group to the surfactant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc57dd45e2865ef4491c9d70fb459c1d
https://pubmed.ncbi.nlm.nih.gov/15330103
https://pubmed.ncbi.nlm.nih.gov/15330103
Publikováno v:
Journal of chromatography. A. 1034(1-2)
Supercritical fluid chromatography (SFC) is capable of separating oligomers of alcohol ethoxylates (AEOs) and propoxylates (APOs) samples with pure carbon dioxide. The instrumental conditions, however, needed for separation necessitate both high temp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15572d89422579e92553d875c2ae0ac3
https://pubmed.ncbi.nlm.nih.gov/15116932
https://pubmed.ncbi.nlm.nih.gov/15116932