Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Stephen Rong"'
Autor:
Luke Buerer, Nathaniel E. Clark, Anastasia Welch, Chaorui Duan, Allison J. Taggart, Brittany A. Townley, Jing Wang, Rachel Soemedi, Stephen Rong, Chien-Ling Lin, Yi Zeng, Adam Katolik, Jonathan P. Staley, Masad J. Damha, Nima Mosammaparast, William G. Fairbrother
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The majority of genic transcription is intronic. Introns are removed by splicing as branched lariat RNAs which require rapid recycling. The branch site is recognized during splicing catalysis and later debranched by Dbr1 in the rate-limiting
Externí odkaz:
https://doaj.org/article/81ba1794519b409e80b2dd49a5ba6bff
Autor:
Chaorui Duan, Truman Mooney, Luke Buerer, Cory Bowers, Stephen Rong, Seong Won Kim, Alger M. Fredericks, Sean F. Monaghan, William G. Fairbrother
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-18 (2024)
Abstract Background The removal of introns occurs through the splicing of a 5′ splice site (5′ss) with a 3′ splice site (3′ss). These two elements are recognized by distinct components of the spliceosome. However, introns in higher eukaryotes
Externí odkaz:
https://doaj.org/article/6f2d53f327de41ca8b4d2eea6922bcd8
Autor:
Stephen Rong, Luke Buerer, Christy L. Rhine, Jing Wang, Kamil J. Cygan, William G. Fairbrother
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Splicing is regulated by cis-acting elements in pre-mRNAs such as exonic or intronic splicing enhancers and silencers. Here the authors show that exonic splicing enhancers are enriched in exons compared to introns due to mutational bias coupled with
Externí odkaz:
https://doaj.org/article/3443e38d261c49c28705c2a31a32ed6b
Autor:
Lauren Alpert Sugden, Elizabeth G. Atkinson, Annie P. Fischer, Stephen Rong, Brenna M. Henn, Sohini Ramachandran
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Selective sweeps are events in which beneficial mutations spread rapidly through a population. Here, Sugden et al. develop SWIF(r), a probabilistic classification framework for detecting and localizing selective sweeps, and apply it to genomic data f
Externí odkaz:
https://doaj.org/article/ea7421382bdb46b1aa16c069bc69f1a7
Publikováno v:
PLoS Biology, Vol 13, Iss 4, p e1002133 (2015)
The authors of "Relatedness, Conflict, and the Evolution of Eusociality" respond to objections raised by Martin Nowak and Benjamin Allen.
Externí odkaz:
https://doaj.org/article/bd7734aaeafc42f49805896aec863c97
Publikováno v:
PLoS Biology, Vol 13, Iss 3, p e1002098 (2015)
The evolution of sterile worker castes in eusocial insects was a major problem in evolutionary theory until Hamilton developed a method called inclusive fitness. He used it to show that sterile castes could evolve via kin selection, in which a gene f
Externí odkaz:
https://doaj.org/article/b4fa89d5ff864c8a9cab6ec79fc00069
Autor:
Stephen Rong, Christopher R. Neil, Anastasia Welch, Chaorui Duan, Samantha Maguire, Ijeoma C. Meremikwu, Malcolm Meyerson, Ben J. Evans, William G. Fairbrother
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Humans coexisted and interbred with other hominins which later became extinct. These archaic hominins are known to us only through fossil records and for two cases, genome sequences. Here, we engineer Neanderthal and Denisovan sequences into thousand
Autor:
David M. Rand, Kerstin Johannesson, Rebecca Elyanow, John T. Burley, Magnus Alm Rosenblad, Henrik Glenner, Anders Blomberg, Alejandro Damian-Serrano, Stephen Rong, Kimberly B. Neil, David A. Ferranti, Joaquin C. B. Nunez
Publikováno v:
Molecular Biology and Evolution
Molecular Biology and Evolution (MBE)
Molecular Biology and Evolution (MBE)
Acorn barnacle adults experience environmental heterogeneity at various spatial scales of their circumboreal habitat, raising the question of how adaptation to high environmental variability is maintained in the face of strong juvenile dispersal and
Autor:
Luke Buerer, William G. Fairbrother, Kamil J. Cygan, Christy L. Rhine, Stephen Rong, Jing Wang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications
Nature Communications
Exonic splicing enhancers (ESEs) are enriched in exons relative to introns and bind splicing activators. This study considers a fundamental question of co-evolution: How did ESE motifs become enriched in exons prior to the evolution of ESE recognitio
Autor:
Joaquin C. B. Nunez, Leif A. Eriksson, Kimberly B. Neil, David A. Ferranti, David M. Rand, Magnus Alm Rosenblad, Stephen Rong, Anders Blomberg, Patrick A. Flight
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The rocky intertidal is a natural laboratory to study how natural selection acts on the genes and proteins responsible for organismal survival and reproduction. Alternative forms of enzymes that differ across the intertidal have been kno