Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Stephen Rayport"'
Autor:
Nao Chuhma, Stephen Rayport
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
The cytoarchitecture of the striatum is remarkably homogeneous, in contrast to the regional variation in striatal functions. Whether differences in the intrinsic membrane properties of striatal neurons contribute to regional heterogeneity has not bee
Externí odkaz:
https://doaj.org/article/081b8cb5db154b35944296390931e3ff
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112204- (2023)
Summary: Dopamine neurons project to the striatum to control movement, cognition, and motivation via slower volume transmission as well as faster dopamine, glutamate, and GABA synaptic actions capable of conveying the temporal information in dopamine
Externí odkaz:
https://doaj.org/article/7e8d646dbbf7439e958f9795c6c8203a
Autor:
Darshini Mahadevia, Rinki Saha, Alessia Manganaro, Nao Chuhma, Annette Ziolkowski-Blake, Ashlea A. Morgan, Dani Dumitriu, Stephen Rayport, Mark S. Ansorge
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The authors show that terminal activity of dopaminergic neurons selectively projecting from the ventral tegmental area to the lateral septum is sufficient for promoting aggression and necessary for establishing baseline aggression in mice.
Externí odkaz:
https://doaj.org/article/bedb5a8b28ab4e4cadccee6c0020bd40
Autor:
Daniel Eskenazi, Lauren Malave, Susana Mingote, Leora Yetnikoff, Samira Ztaou, Vlad Velicu, Stephen Rayport, Nao Chuhma
Publikováno v:
Frontiers in Neural Circuits, Vol 15 (2021)
Discovered just over 20 years ago, dopamine neurons have the ability to cotransmit both dopamine and glutamate. Yet, the functional roles of dopamine neuron glutamate cotransmission and their implications for therapeutic use are just emerging. This r
Externí odkaz:
https://doaj.org/article/e89b1711767b475d97d730fe21265fe7
Autor:
Nao Chuhma, Susana Mingote, Leora Yetnikoff, Abigail Kalmbach, Thong Ma, Samira Ztaou, Anna-Claire Sienna, Sophia Tepler, Jean-Francois Poulin, Mark Ansorge, Rajeshwar Awatramani, Un Jung Kang, Stephen Rayport
Publikováno v:
eLife, Vol 7 (2018)
Dopamine neurons have different synaptic actions in the ventral and dorsal striatum (dStr), but whether this heterogeneity extends to dStr subregions has not been addressed. We have found that optogenetic activation of dStr dopamine neuron terminals
Externí odkaz:
https://doaj.org/article/4e469572ca9849e9a76fbd0fad4942ab
Autor:
Susana Mingote, Nao Chuhma, Abigail Kalmbach, Gretchen M Thomsen, Yvonne Wang, Andra Mihali, Caroline Sferrazza, Ilana Zucker-Scharff, Anna-Claire Siena, Martha G Welch, José Lizardi-Ortiz, David Sulzer, Holly Moore, Inna Gaisler-Salomon, Stephen Rayport
Publikováno v:
eLife, Vol 6 (2017)
Dopamine neurons in the ventral tegmental area use glutamate as a cotransmitter. To elucidate the behavioral role of the cotransmission, we targeted the glutamate-recycling enzyme glutaminase (gene Gls1). In mice with a dopamine transporter (Slc6a3)-
Externí odkaz:
https://doaj.org/article/4a64a1422aff4dda921b0d4baff5b1f9
Publikováno v:
Bio-Protocol, Vol 7, Iss 1 (2017)
Functional connectivity in a neural circuit is determined by the strength, incidence, and neurotransmitter nature of its connections (Chuhma, 2015). Using optogenetics the functional synaptic connections between an identified population of neurons an
Externí odkaz:
https://doaj.org/article/96630f5fb7e94cf8ad9d1a46fa2eebb4
Autor:
Celia Gellman, Jeff A. Beeler, Holly Moore, Abigail Kalmbach, Stephen Rayport, Benjamin Y. Klein, Roseanna M. Zanca, Devry Mourra, Peter A. Serrano, Susana Mingote, Rebecca Ravenelle, Nesha S. Burghardt
Publikováno v:
Biol Psychiatry
Background Increased physical activity is a common feature of anorexia nervosa (AN). Although high activity levels are associated with greater risk of developing AN, particularly when combined with dieting, most individuals who diet and exercise main
Autor:
Cátia M. Teixeira, Mark S. Ansorge, John F. Smiley, Robert H. Edwards, Edenia C. Menezes, Nao Chuhma, Relish Shah, Cynthia Bleiwas, Francisco X. Castellanos, Stephen Rayport, Catarina Cunha, Rebecca P. Seal
Publikováno v:
Molecular psychiatry
Serotonin and dopamine are associated with multiple psychiatric disorders. How they interact during development to affect subsequent behavior remains unknown. Knockout of the serotonin transporter or postnatal blockade with selective serotonin reupta
Publikováno v:
SSRN Electronic Journal.