Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Stephen R.J. Salton"'
Autor:
Mengdan Xing, Zhe Li, Xiaojing Ye, Stephen R.J. Salton, Jin-lin Zou, Purva Bali, Yamei Tang, Wei-Jye Lin, Cheng Jiang, Noël A. Warren, Shuyu Zheng, Jingru Wu, Yan Zhao
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-11 (2021)
Translational Psychiatry
Translational Psychiatry
The release of neuropeptides from dense core vesicles (DCVs) modulates neuronal activity and plays a critical role in cognitive function and emotion. The granin family is considered a master regulator of DCV biogenesis and the release of DCV cargo mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::769254c9cab24bd8316cc376dc6e1fb4
https://doaj.org/article/385eba863748422bbaad7d12df8237a4
https://doaj.org/article/385eba863748422bbaad7d12df8237a4
Autor:
Bhavani S. Sahu, Stephen R.J. Salton, Megin E. Nguyen, Yuk Y. Sham, Vinayak Ghosh, Pedro Rodriguez, Maria Razzoli, Jean Pierre Pallais, Alessandro Bartolomucci
Publikováno v:
Cellular and Molecular Life Sciences
The TLQP-21 neuropeptide has been implicated in functions as diverse as lipolysis, neurodegeneration and metabolism, thus suggesting an important role in several human diseases. Three binding targets have been proposed for TLQP-21: C3aR1, gC1qR and H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2925dd9f052bfffeadeed33421e79258
https://pubmed.ncbi.nlm.nih.gov/34626205
https://pubmed.ncbi.nlm.nih.gov/34626205
Autor:
Wei-Jye Lin, Emmy Sakakibara, Stephen R.J. Salton, Cheng Jiang, Jun Wang, Giulio Maria Pasinetti
Publikováno v:
Annals of the New York Academy of Sciences. 1455:196-205
Recent studies suggest that bioactive dietary polyphenol preparation (BDPP) and individual polyphenolic compounds ameliorate stress-induced depression-like behaviors, but the underlying molecular mechanisms are incompletely understood. VGF (non-acron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6f93b7c94509fc8ed29018c6116d587
https://doi.org/10.1111/nyas.14098
https://doi.org/10.1111/nyas.14098
Autor:
Erin S. Calipari, Song Zhang, Madeline L. Pfau, Hossein Aleyasin, Ming-Hu Han, Allyson K. Friedman, He Liu, Jeffrey M. Friedman, Nikos Tzavaras, Marshall Crumiller, Stephen R.J. Salton, Stacy M. Ku, Michelle He, Hongxing Zhang, Sarah E. Montgomery, Alexander R. Nectow, Jun Li Cao, Cheng Jiang, Barbara Juarez, Scott J. Russo, Eric J. Nestler, Dipesh Chaudhury, Carole Morel
Publikováno v:
Biological Psychiatry. 85:226-236
Background Homeostatic plasticity in mesolimbic dopamine (DA) neurons plays an essential role in mediating resilience to social stress. Recent evidence implicates an association between stress resilience and projections from the locus coeruleus (LC)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9d419baa3f07127355dc596f1d6c5c1
https://doi.org/10.1016/j.biopsych.2018.08.020
https://doi.org/10.1016/j.biopsych.2018.08.020
Autor:
Alexander W. Charney, Phillip H. Comella, Amanda K. Fakira, Weiping Ma, Pavel Katsel, Siddharth P. Hariharan, Michelle E. Ehrlich, Cheng Jiang, Pei Wang, Ben Shackleton, Ying-Chih Wang, Robert D. Blitzer, Sam Gandy, Eimear E. Kenny, Wei-Jye Lin, Eric E. Schadt, Kiran Girdhar, Duc M. Duong, Allan I. Levey, Jean-Vianney Haure-Mirande, Noam D. Beckmann, Stephen R.J. Salton, James J. Lah, Jun Zhu, Gillian M. Belbin, Bin Zhang, Tomas Fanutza, Vahram Haroutunian, Nicholas T. Seyfried, Eric B. Dammer, Mickael Audrain, Zhidong Tu, Ariella Cohain, Minghui Wang
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Though discovered over 100 years ago, the molecular foundation of sporadic Alzheimer’s disease (AD) remains elusive. To better characterize the complex nature of AD, we constructed multiscale causal networks on a large human AD multi-omics dataset,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1acee335bb7d5db6fc76c7cbfc84d72b
http://europepmc.org/articles/PMC7414858
http://europepmc.org/articles/PMC7414858
Autor:
Stephen R.J. Salton, Michelle E. Ehrlich, Cheng Jiang, Peter S. Heeger, Mickael Audrain, Eric E. Schadt, Noam D. Beckmann, Sam Gandy, Wei-Jye Lin, Siddharth P. Hariharan, Farida El Gaamouch
Publikováno v:
Molecular Neurodegeneration
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-19 (2020)
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-19 (2020)
Background Multiomic studies by several groups in the NIH Accelerating Medicines Partnership for Alzheimer’s Disease (AMP-AD) identified VGF as a major driver of Alzheimer’s disease (AD), also finding that reduced VGF levels correlate with mean a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::235fa89df926d3bda8fe7b8cc23b75f0
http://europepmc.org/articles/PMC6954537
http://europepmc.org/articles/PMC6954537
Autor:
Cheng Jiang, Stephen R.J. Salton
Neurotrophic growth factors (neurotrophins), other growth factors, and their receptors and downstream signaling pathways have long been appreciated to play critical roles in the modulation of depressive behavior and the regulation of antidepressant e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00dd1a0bb1d449d81013a4115847a326
https://doi.org/10.1016/b978-0-12-814037-6.00010-0
https://doi.org/10.1016/b978-0-12-814037-6.00010-0
Autor:
Gustavo Turecki, Stephen R.J. Salton, Benoit Labonté, Carol A. Tamminga, Cheng Jiang, Eric J. Nestler, Scott J. Russo, Wei Jye Lin
Publikováno v:
Neuropsychopharmacology. 44:971-981
Patients with major depressive disorder (MDD) often have structural and functional deficits in the ventromedial prefrontal cortex (vmPFC), but the underlying molecular pathways are incompletely understood. The neuropeptide precursor VGF (non-acronymi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0b195d1902a2ba8c87c6216f16e0767
https://doi.org/10.1038/s41386-018-0277-4
https://doi.org/10.1038/s41386-018-0277-4
Publikováno v:
Journal of Molecular Neuroscience. 68:504-509
Members of the neurotrophin family and in particular brain-derived neurotrophic factor (BDNF) regulate the response to rapid- and slow-acting chemical antidepressants and voluntary exercise. Recent work suggests that rapid-acting antidepressants that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf39e8de3c16ab1391bc6216017cde62
https://doi.org/10.1007/s12031-018-1124-0
https://doi.org/10.1007/s12031-018-1124-0
Autor:
Stephen R.J. Salton, Cheng Jiang, Christoph Buettner, Wei Jye Lin, Masato Sadahiro, Andrew Shin
Publikováno v:
Neuropeptides. 64:75-83
Germline ablation of VGF, a secreted neuronal, neuroendocrine, and endocrine peptide precursor, results in lean, hypermetabolic, and infertile adult mice that are resistant to diet-, lesion-, and genetically-induced obesity and diabetes (Hahm et al.,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb05beaf47872b7c52443c2c551c71ed
https://doi.org/10.1016/j.npep.2016.12.005
https://doi.org/10.1016/j.npep.2016.12.005