Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Stephen R. Wellard"'
Autor:
Michael V. Tran, James W. Ferguson, Lauren E. Cote, Daria Khuntsariya, Richard D. Fetter, Jennifer T. Wang, Stephen R. Wellard, Maria D. Sallee, Mariya Genova, Sani Eskinazi, Maria M. Magiera, Carsten Janke, Tim Stearns, Zdenek Lansky, Kang Shen, Jérémy Magescas, Jessica L. Feldman
Publikováno v:
bioRxiv
SummaryMicrotubule doublets (MTDs) are a well conserved compound microtubule structure found primarily in cilia. However, the mechanisms by which MTDs form and are maintainedin vivoremain poorly understood. Here, we characterize microtubule-associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ee5bf1d6ac65979de522b3473fc41b7
https://europepmc.org/articles/PMC9980146/
https://europepmc.org/articles/PMC9980146/
Publikováno v:
Molecular Biology of the Cell. 33
Homologous recombination (HR) is an essential meiotic process that contributes to the genetic variation of offspring and ensures accurate chromosome segregation. Recombination is facilitated by the formation and repair of programmed DNA double-strand
Autor:
Philip W. Jordan, Stephen R. Wellard, Stephen A. Murray, Matthew Mckay, Yujiao Zhang, Xueqi Zhao, Chris Shults
Publikováno v:
EMBO Rep
The establishment of bipolar spindles during meiotic divisions ensures faithful chromosome segregation to prevent gamete aneuploidy. We analyzed centriole duplication, as well as centrosome maturation and separation during meiosis I and II using mous
Publikováno v:
J Cell Sci
Precise control of chromosome dynamics during meiosis is critical for fertility. A gametocyte undergoing meiosis coordinates formation of the synaptonemal complex (SC) to promote efficient homologous chromosome recombination. Subsequent disassembly o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73af2002ceec2a883bb91728dc617041
https://europepmc.org/articles/PMC7725601/
https://europepmc.org/articles/PMC7725601/
Autor:
Gang Cheng, Florencia Pratto, Stephen R. Wellard, Kwan-Wood Gabriel Lam, Kevin Brick, Jeffrey M. Cloutier, Philip W. Jordan, Daisy Dahiya, R. Daniel Camerini-Otero
Publikováno v:
Daisy Dahiya
Genetic recombination generates novel trait combinations, and understanding how recombination is distributed across the genome is key to modern genetics. The PRDM9 protein defines recombination hotspots; however, megabase-scale recombination patterni
Autor:
Gang Cheng, Daisy Dahiya, R. Daniel Camerini-Otero, Stephen R. Wellard, Gabriel Lam, Kevin Brick, Florencia Pratto, Philip W. Jordan, Jeffrey M. Cloutier
Publikováno v:
SSRN Electronic Journal.
Summary:Genetic recombination generates novel trait combinations and understanding how recombination is distributed across the genome is key to modern genetics. The PRDM9 protein defines recombination hotspots, however megabase-scale recombination pa
Precise control of chromosome dynamics during meiosis is critical for fertility. A gametocyte undergoing meiosis coordinates formation of the synaptonemal complex (SC) to promote efficient homologous chromosome recombination. Subsequent disassembly o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e68281a00ca3dea5494a7bae4da161b
https://doi.org/10.1101/868836
https://doi.org/10.1101/868836
Publikováno v:
Journal of visualized experiments : JoVE. (132)
Meiotic progression in males is a process that requires the concerted action of a number of highly regulated cellular events. Errors occurring during meiosis can lead to infertility, pregnancy loss or genetic defects. Commencing at the onset of puber