Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Stephen R. Lutz"'
Autor:
Ethan Clark, Gwendolyn M Wilmes, Rachel S Quesenberry, Sergey V Shulga-Morskoy, Violetta Medik, Stuart W. Hicks, Megan E Lewis, Stephen R Lutz, Anthony B Cooper, Hugh H. Russell, Elizabeth E. Reczek, Paulina Kocjan, Jesse A Stevenson, Kimberly L Carey
Publikováno v:
mAbs
Antibody combination therapeutics (ACTs) are polyvalent biopharmaceuticals that are uniquely suited for the control of complex diseases, including antibiotic resistant infectious diseases, autoimmune disorders and cancers. However, ACTs also represen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e21b4b9f26ad2a6a895ed8b21f87f656
Autor:
Xeni Mitropoulos, Jae Won Chang, Daniel A. Haber, Jeffrey Settleman, Wanjuan Yang, I. Richard Thompson, Julio Saez-Rodriguez, Nathanael S. Gray, Olivier Delattre, Jeffrey A. Engelman, Qingsong Liu, Sonja J. Heidorn, José Baselga, Michael R. Stratton, Karl P. Lawrence, Helen Davies, Stephen R. Lutz, Li Chen, Helen Thi, Graham R. Bignell, Randy J. Milano, Anne McLaren-Douglas, Anahita Dastur, Sridhar Ramaswamy, Sreenath V. Sharma, Jesse A. Stevenson, Patricia Greninger, Jessica L. Boisvert, King Wai Lau, Xi Luo, Tatiana Mironenko, Xianming Deng, Christopher Greenman, Fiona Kogera, P. Andrew Futreal, Tinghu Zhang, Patrick O’Brien, Syd Barthorpe, F Jewitt, Ultan McDermott, Hwan Geun Choi, Mathew J. Garnett, Ivan Stamenkovic, Francesco Iorio, Wooyoung Hur, Stacey Price, Jorge Soares, Laura Richardson, Wenjun Zhou, Cyril H. Benes, Ah Ting Tam, Adam Butler, Elena J. Edelman, Didier Surdez
Publikováno v:
Nature
Nature, vol. 483, no. 7391, pp. 570-575
Nature, vol. 483, no. 7391, pp. 570-575
Clinical responses to anticancer therapies are often restricted to a subset of patients. In some cases, mutated cancer genes are potent biomarkers for responses to targeted agents. Here, to uncover new biomarkers of sensitivity and resistance to canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d30c7a49863ef53126248c5b26aafba
http://europepmc.org/articles/PMC3349233
http://europepmc.org/articles/PMC3349233
Autor:
Stephen R. Lutz, Michael Lewis, Jaime Darce, Roy Scialdone, Evans Burford, Herbert Haack, Krystyna Zuberek Hincman, Michael R. Nelson, Matthew Ren Silver, Christopher A. Manning
Publikováno v:
Cancer Research. 76:4595-4595
The epidermal growth factor receptor (EGFR) is a cell-surface receptor for members of the epidermal growth factor family (EGF-family). EGFR dimerizes upon ligand binding, which leads to autophosphorylation, downstream signaling and ultimately interna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e796e66f39adba3d1bdc8e260807fac5
https://doi.org/10.1158/1538-7445.am2016-4595
https://doi.org/10.1158/1538-7445.am2016-4595