Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Stephen R. Jaspers"'
Autor:
Brent Meengs, Susan H. Julien, Ursula Garrigues, Thomas R. Bukowski, Stacey R. Dillon, Mark W. Rixon, Kenneth B. Lewis, Anitra C. Wolf, Mark Snavely, Mark F. Maurer, Stephen R. Jaspers, Brenda Stevens, Nels Hamacher
Publikováno v:
mAbs. 4:69-83
Interleukin-21 (IL-21) is a type I four-helical bundle cytokine that exerts a variety of significant effects on many hematopoietic cells, including T and B lymphocytes and natural killer cells. IL-21 is produced predominantly by CD4+ T cells and natu
Autor:
Donald C. Foster, Patricia A. Mckernan, Lena Yao, Stephen R. Jaspers, James West, Karen L. Madden, Ty Brender, Laura J. Jelinek, Wenfeng Xu, Cameron S. Brandt, Crystal Jones, Julia Parrish-Novak, Yasmin A. Chandrasekher
Publikováno v:
Journal of Biological Chemistry. 277:47517-47523
Cytokines that signal through Class II receptors form a distinct family that includes the interferons and interleukin 10 (IL-10). Recent identification of several IL-10 homologs has defined a cytokine subfamily that includes AK155, IL-19, IL-20, IL-2
Autor:
Si Lok, Darrell C. Conklin, Theodore E. Whitmore, Stephen R. Jaspers, Catherine Lofton-Day, Betty A. Haldeman, Andrew Ching
Publikováno v:
Genomics. 60:50-56
A new member of the insulin gene superfamily (INSL5) was identified by searching EST databases for the presence of the conserved insulin B-chain cysteine motif. Human and murine INSL5 are both polypeptides of 135 amino acids, matching the classical s
Autor:
Ruth Gill, Raymond A. Pederson, Irene Jane Bremsak, Gary L. McKnight, Cuilan Nian, Stephen R. Jaspers, Francis C. Lynn, Richard W. Gelling, Christopher H.S. McIntosh, Simon A. Hinke
Publikováno v:
Endocrinology. 140:398-404
GIP is an important insulinotropic hormone (incretin) that has also been implicated in fat metabolism. There is controversy regarding the actions of GIP on adipocytes. In the current study, the existence of GIP receptors and effects of GIP on lipolys
Publikováno v:
Molecular and Cellular Biochemistry. 136:29-34
Freshly isolated ventricular myocytes have been used extensively as an adult cardiac model system. Due to their inability to undergo cytokinesis in vitro and their dedifferentiated properties in long-term culture, they can not be used for extended st
Post-receptor defect accounts for phosphorylase hypersensitivity in cultured diabetic cardiomyocytes
Publikováno v:
Molecular and Cellular Biochemistry. 117:63-70
The basis for the hypersensitive response of glycogen phosphorylase to epinephrine stimulation was investigated in adult rat cardiomyocytes isolated from normal and alloxan-diabetic animals. To assess potential G-protein involvement in the response,
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 262:H649-H653
The basis of catecholamine-induced activation of glycogen phosphorylase was investigated in adult rat cardiomyocytes isolated from normal and alloxan-diabetic animals. Cells derived from diabetic animals exhibited a hypersensitive response to epineph
Publikováno v:
Thrombosis Research. 63:427-432
Autor:
Thomas B. Miller, Stephen R. Jaspers
Publikováno v:
Molecular and Cellular Biochemistry. 101:167-174
Protein phosphatase 2A1 was purified from rat skeletal muscle and used to produce antisera to the three subunits of the holoenzyme. Affinity purified antibodies specific for the subunits of the phosphatase enzyme were found to recognize the type 2A1
Autor:
Thomas M. Roberts, Bruce L. Martin, Lilian K. Shahrik, David C. Pallas, David L. Brautigan, Stephen R. Jaspers, Thomas B. Miller
Publikováno v:
Cell. 60:167-176
We have purified the 36 and 63 kd cellular proteins known to associate with polyomavirus middle and small tumor (T) antigens and SV40 small t antigen. Microsequencing of the 36 kd protein indicated that it was probably identical to the catalytic subu