Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Stephen R. Igo"'
Autor:
Brian A. Bruckner, Dennis K. Wang, Alessandro Grattoni, Stephen R. Igo, Matteo Hirsch, Carly S. Filgueira, Daryl G. Schulz
Publikováno v:
Advanced drug delivery reviews.
The pericardium, which surrounds the heart, provides a unique enclosed volume and a site for the delivery of agents to the heart and coronary arteries. While strategies for targeting the delivery of therapeutics to the heart are lacking, various tech
Autor:
Alan B. Lumsden, Jean Bismuth, Kyle Autry, Avni P. Patel, Hector W. de Beaufort, Eric Y. Yang, Stephen H. Little, Stephen R. Igo, Mohamad G. Ghosn, Domenico Spinelli, Santi Trimarchi, Dipan J. Shah, Matthew S. Jackson
Publikováno v:
The Journal of thoracic and cardiovascular surgery. 157(2)
Objective Four-dimensional flow cardiovascular magnetic resonance may improve assessment of hemodynamics in patients with aortic dissection. The purpose of this study was to evaluate the feasibility and accuracy of 4-dimensional flow cardiovascular m
Autor:
William B. Kline, Pietro Valsecchi, Karen E. Chin, Stephen R. Igo, Matthew S. Jackson, Robert C. Schutt, Dimitrios Maragiannis, Dipan J. Shah, Kyle Autry, Thomas E. Lindsey, Stephen H. Little
Publikováno v:
Cardiovascular Engineering and Technology. 5:13-24
We sought to build a robust pulsatile flow model permitting comparison of 3D Color Doppler and phase contrast magnetic resonance (PCMR) flow and orifice area measurements of prosthetic valve function that would provide an in vitro gold standard for e
Autor:
Matthew S. Jackson, Thomas J. Ryan, Saurabh Datta, Nathalie De Michelis, Sanjay Rajagopalan, Paaladinesh Thavendiranathan, Stephen H. Little, Stephen R. Igo, Shizhen Liu, Mani A. Vannan
Publikováno v:
Circulation: Cardiovascular Imaging. 6:125-133
Background— The aim of this study was to test the accuracy of an automated 3-dimensional (3D) proximal isovelocity surface area (PISA) (in vitro and patients) and stroke volume technique (patients) to assess mitral regurgitation (MR) severity using
Autor:
Stephen H. Little, Stephen R. Igo, Jiaqiong Xu, Rey P. Vivo, Selim R. Krim, Ankit Patel, William A. Zoghbi
Publikováno v:
JACC: Cardiovascular Imaging. 5(5):478-483
A reliable method for the assessment of the mitral valve (MV) area is essential for the management of patients with a prosthetic MV. In this study, we assess the feasibility of 3-dimensional (3D) echocardiography to directly measure the mechanical MV
Autor:
Craig J. Hartley, Sunčica Čanić, Stephen R. Igo, William A. Zoghbi, Annalisa Quaini, Roland Glowinski, Stephen H. Little
Publikováno v:
Journal of Biomechanics. 45:310-318
This work presents a validation of a fluid-structure interaction computational model simulating the flow conditions in an in vitro mock heart chamber modeling mitral valve regurgitation during the ejection phase during which the trans-valvular pressu
Autor:
Stephen R. Igo, Stephen H. Little, Annalisa Quaini, Sunčica Čanić, William A. Zoghbi, Giovanna Guidoboni, Craig J. Hartley, Roland Glowinski
Publikováno v:
Cardiovascular Engineering and Technology. 2:77-89
3D color Doppler echocardiography has recently been employed to evaluate 3D proximal isovelocity surface area (PISA) and vena contracta (VC) area measures of regurgitant valve severity. Computational fluid dynamics (CFD) modeling may provide insight
Autor:
Marti L. McCulloch, Stephen R. Igo, Rahul Kumar, Jiaqiong Xu, Stephen H. Little, William A. Zoghbi, Craig J. Hartley, Bahar Pirat
Publikováno v:
JACC: Cardiovascular Imaging. 1(6):695-704
Objectives Our goal was to prospectively compare the accuracy of real-time three-dimensional (3D) color Doppler vena contracta (VC) area and two-dimensional (2D) VC diameter in an in vitro model and in the clinical assessment of mitral regurgitation
Autor:
Marti L. McCulloch, Stephen R. Igo, William A. Zoghbi, Yukihiko Nosé, Stephen H. Little, Craig J. Hartley
Publikováno v:
Ultrasound in Medicine & Biology. 34:647-654
We describe the development of a cardiac flow model and imaging chamber to permit Doppler assessment of complex and dynamic flow events. The model development included the creation of a circulatory loop with variable compliance and resistance; the cr
Autor:
Stephen H. Little, Stephen R. Igo, Craig J. Hartley, William A. Zoghbi, Yukihiko Nosé, Marti L. McCulloch, Bahar Pirat
Publikováno v:
The American Journal of Cardiology. 99:1440-1447
The 2-dimensional (2D) color Doppler (2D-CD) proximal isovelocity surface area (PISA) method assumes a hemispheric flow convergence zone to estimate transvalvular flow. Recently developed 3-dimensional (3D)-CD can directly visualize PISA shape and su