Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Stephen R. Coates"'
Autor:
Debbie Drane, Megan Barnden, Eugene Maraskovsky, Gervase Barbara A, Rebecca Gibson, Stephen R. Coates, Russell L. Basser, Sue Mitchell, David Shaw, Alan Moskwa, Michael Houghton
Publikováno v:
Human Vaccines. 5:151-157
The disease burden and public health impact of chronic HCV infection continues to be a major problem globally. Current treatment for chronic HCV infection is not effective in all patients and is frequently associated with unacceptable side effects. C
Autor:
Kevin Crawford, Michael Houghton, Mark Wininger, Colin S. McCoin, Hall John A, John M. Polo, Doris Coit, Michael Vajdy, Christine Dong, Angelica Medina-Selby, Yi-Fei Zhu, Stephen R. Coates, Debbie Drane, Philip Ng, Taewoo Kwon, Jang Han, Yin-Ling Lin, Mark Selby, David Chien
Publikováno v:
Journal of Virology. 82:7492-7503
Broad, multispecific CD4 + and CD8 + T-cell responses to the hepatitis C virus (HCV), as well as virus-cross-neutralizing antibodies, are associated with recovery from acute infection and may also be associated in chronic HCV patients with a favorabl
Autor:
Charles M. Rice, Jane A. McKeating, Sergio Abrignani, Mark Wininger, Stephen R. Coates, Matthew J. Evans, Kevin Crawford, Yiu-Lian Fong, Michael Houghton, David Chien, Peter Balfe, Zania Stamataki, Christine Dong
Publikováno v:
Vaccine. 25:7773-7784
Neutralizing antibody responses elicited during infection generally confer protection from infection. Hepatitis C virus (HCV) encodes two glycoproteins E1 and E2 that are essential for virus entry and are the major target for neutralizing antibodies.
Autor:
Stephen R. Coates, Qui-Lim Choo, Hyun Chul Song, Takashi Harada, Piero Pileri, Konrad Stadler, Michael Houghton, John M. Polo, Byoung J. Yoo, Catherine Greer, Mi Young Seo, Jang H. Han, Sergio Abrignani, Yasushi Uematsu, Markus Eickmann, Rino Rappuoli
Publikováno v:
Journal of Virology
We have expressed and characterized the severe acute respiratory syndrome coronavirus (SARS-CoV) spike protein in cDNA-transfected mammalian cells. The full-length spike protein (S) was newly synthesized as an endoglycosidase H (endo H)-sensitive gly
Autor:
Harold Legg, Leonidas Stamatatos, Mark Wininger, Elaine Kan, John J. Donnelly, Indresh K. Srivastava, Stephen R. Coates, Anne Fong, Louisa Leung, Jeffrey B. Ulmer, Susan W. Barnett
Publikováno v:
Journal of Virology. 76:2835-2847
Human immunodeficiency virus (HIV) continues to be a major public health problem throughout the world, with high levels of mortality and morbidity associated with AIDS. Considerable efforts to develop an effective vaccine for HIV have been directed t
Autor:
Arnab Basu, Stephen R. Coates, Arup Banerjee, Sharon E. Frey, Sergio Abrignani, Michael Houghton, Keith Meyer, Robert B. Belshe, Ranjit Ray
Publikováno v:
The Journal of Infectious Diseases
Hepatitis C virus (HCV) envelope glycoproteins E1 and E2 were used with MF59 adjuvant as a candidate vaccine for a phase 1 safety and immunogenicity trial. Ten of 41 vaccinee serum samples displayed a neutralization titer of > or =1:20 against vesicu
Autor:
Jang H. Han, Paola Rinella, Ranjit Ray, Domenico Rosa, Michael Houghton, David Chien, Adrian M. Di Bisceglie, Viola Schultze, Heather Hill, Mark Wolff, Bruce F. Scharschmidt, Robert B. Belshe, Sharon E. Frey, Sergio Abrignani, Stephen R. Coates, Piero Pileri
Background Hepatitis C virus (HCV) causes chronic liver disease that often leads to cirrhosis and hepatocellular carcinoma. In animal studies, chimpanzees were protected against chronic infection following experimental challenge with either homologou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a495941cec29608a4f8c986bed0240b7
https://europepmc.org/articles/PMC2923449/
https://europepmc.org/articles/PMC2923449/
Publisher Summary The majority of individuals infected with hepatitis C virus (HCV) develop chronic infections and approximately 20–30% of those individuals experience liver disease. Typically, the cellular and humoral arms of the immune system pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::851808112f45a5a84950126572caa85c
https://doi.org/10.1016/s1874-5326(00)80011-3
https://doi.org/10.1016/s1874-5326(00)80011-3
Autor:
Leonard B. Weiner, Fawzia A. Saeed, Randall D. Madsen, Stephen R. Coates, James A. North, Julia A. McMillan
Publikováno v:
American Journal of Clinical Pathology. 89:95-99
Throat swabs from patients with pharyngitis and sputum specimens from patients with atypical pneumonia were tested for the presence of a Mycoplasma pneumoniae polypeptide with a molecular weight of 43,000 with the use of an M. pneumoniae species-spec
Publikováno v:
American Journal of Clinical Pathology. 79:206-210
Calbiochem-Behring, Enzygnost™-Rubella is an enzyme-linked immunosorbent assay (ELISA) for the determination of IgG antibodies to rubella virus. Two procedures, screening and quantitative, were used for the measurement of rubella anti- bodies in a