Zobrazeno 1 - 10
of 192
pro vyhledávání: '"Stephen R Hammes"'
Autor:
Zhiguang Xiao, Stephen R. Hammes
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103270- (2021)
Summary: Neutrophil elastase (NE) promotes multiple stages of tumorigenesis. However, little is known regarding the molecular mechanisms underlying its stimulatory role. This study shows that NE triggers dose-dependent ERK signaling and cell migratio
Externí odkaz:
https://doaj.org/article/04603845ad5d458e8807b2348343915f
Autor:
Zachary K. Christian, Kimmo J. Hatanpaa, Richard J. Auchus, Stephen R. Hammes, Ankur R. Patel, Bruce E. Mickey
Publikováno v:
Interdisciplinary Neurosurgery, Vol 21, Iss , Pp 100777- (2020)
Background: The majority of prolactin-secreting pituitary macroadenomas are effectively managed with dopamine-agonist therapy alone. Although surgical resection and radiotherapy are second- and third-line treatment options, there remains a paucity of
Externí odkaz:
https://doaj.org/article/d9bc0acb8de94a99816bf76aa0ae0ecb
Autor:
Briaunna M N Minor, Dana LeMoine, Christina Seger, Erin Gibbons, Jules Koudouovoh, Manisha Taya, Daniel Kurtz, Yan Xu, Stephen R Hammes
Publikováno v:
Endocrinology. 164
Lymphangioleiomyomatosis (LAM) is a rare cystic lung disease caused by smooth muscle cell-like tumors containing tuberous sclerosis (TSC) gene mutations and found almost exclusively in females. Patient studies suggest LAM progression is estrogen depe
Autor:
Stephen R. Hammes, Martha Susiarjo, Kent L. Nastiuk, Jessica Ackerman, Javier Rangel-Moreno, Maria de la Luz Garcia-Hernandez, Aerken Maolake, Christina Seger, Xiaoting Ma, Irina Lerman
Supplementary Figure 3. Epigenetic repression of endogenous NE inhibitors in LNCaP cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3810422e1f04ffca0e9810facf2d50f6
https://doi.org/10.1158/1541-7786.22516144
https://doi.org/10.1158/1541-7786.22516144
Autor:
Stephen R. Hammes, Martha Susiarjo, Kent L. Nastiuk, Jessica Ackerman, Javier Rangel-Moreno, Maria de la Luz Garcia-Hernandez, Aerken Maolake, Christina Seger, Xiaoting Ma, Irina Lerman
Supplementary Figure 2. EGF does not induce SERPINB1 expression in prostate cancer cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::582fa059e0428f932dd0824308bdee86
https://doi.org/10.1158/1541-7786.22516147
https://doi.org/10.1158/1541-7786.22516147
Autor:
Stephen R. Hammes, Aritro Sen, John J. Krolewski, Kent L. Nastiuk, Chunliu Pan, Luis Chiriboga, Javier Rangel-Moreno, Maria de la Luz Garcia-Hernandez, Irina Lerman
High power image of neutrophil elastase localization in a xenograft.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42468a50546c058091c3b85912a8ef82
https://doi.org/10.1158/1541-7786.22515469
https://doi.org/10.1158/1541-7786.22515469
Autor:
Stephen R. Hammes, Martha Susiarjo, Kent L. Nastiuk, Jessica Ackerman, Javier Rangel-Moreno, Maria de la Luz Garcia-Hernandez, Aerken Maolake, Christina Seger, Xiaoting Ma, Irina Lerman
Granulocytic myeloid infiltration and resultant enhanced neutrophil elastase (NE) activity is associated with poor outcomes in numerous malignancies. We recently showed that NE expression and activity from infiltrating myeloid cells was high in human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4935fd1ef16ed7a24a568709251515e
https://doi.org/10.1158/1541-7786.c.6541297
https://doi.org/10.1158/1541-7786.c.6541297
Autor:
Stephen R. Hammes, Aritro Sen, John J. Krolewski, Kent L. Nastiuk, Chunliu Pan, Luis Chiriboga, Javier Rangel-Moreno, Maria de la Luz Garcia-Hernandez, Irina Lerman
Tissue infiltration and elevated peripheral circulation of granulocytic myeloid-derived cells is associated with poor outcomes in prostate cancer and other malignancies. Although myeloid-derived cells have the ability to suppress T-cell function, lit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::480ed5940a7583db082c1db5bac03beb
https://doi.org/10.1158/1541-7786.c.6541093
https://doi.org/10.1158/1541-7786.c.6541093
Autor:
Stephen R. Hammes, Martha Susiarjo, Kent L. Nastiuk, Jessica Ackerman, Javier Rangel-Moreno, Maria de la Luz Garcia-Hernandez, Aerken Maolake, Christina Seger, Xiaoting Ma, Irina Lerman
Supplementary Figure 1. SERPINB1 expression is reduced in Pten-null compared to wild type mouse prostates.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4ee9b23be949a91ef096670b6581d04
https://doi.org/10.1158/1541-7786.22516150.v1
https://doi.org/10.1158/1541-7786.22516150.v1
Publikováno v:
Case Reports in Endocrinology, Vol 2018 (2018)
Von Hippel-Lindau (VHL) disease, caused by germline mutations in the VHL gene, is characterized by metachronously occurring tumors including pheochromocytoma, renal cell carcinoma (RCC), and hemangioblastoma. Although VHL disease leads to reduced lif
Externí odkaz:
https://doaj.org/article/cf991c77fab8402295fadb0719513e59