Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Stephen R, Smalley"'
Autor:
Kathleen D. Danenberg, Christine Cripps, James A. Martensen, Robert J. Mayer, Thomas Winder, Tyvin A. Rich, Stephen R. Smalley, Wu Zhang, Al B. Benson, Heinz-Josef Lenz, Jacqueline Benedetti, Cathryn Rankin, Charles D. Blanke, Pierre Oliver Bohanes, Karen W. Makar, Cornelia M. Ulrich
Publikováno v:
Clinical Cancer Research. 21:1583-1590
Purpose: We tested whether 18 polymorphisms in 16 genes (GSTP1, COX2, IL10, EGFR, EGF, FGFR4, CCDN1, VEGFR2, VEGF, CXCR2, IL8, MMP3, ICAM1, ERCC1, RAD51, and XRCC3) would predict disease-free survival (DFS), overall survival (OS), and toxicity in the
Autor:
Aram F. Hezel, Katherine A. Guthrie, Cynthia G. Leichman, Howard S. Hochster, Heinz-Josef Lenz, Matthew A. Beldner, Shannon McDonough, Mario R. Velasco, Kevin G. Billingsley, Stephen R. Smalley, Charles D. Blanke
Background Neoadjuvant chemoradiation (NCRT) is standard treatment for locally advanced rectal cancer. Pathologic complete response (pCR) has associated with improved survival. In modern phase III trials of NCRT, pCR ranges from 10% to 20%. Cetuximab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f883377d89e50a9ba6df5e922e379b0d
https://europepmc.org/articles/PMC6598683/
https://europepmc.org/articles/PMC6598683/
Autor:
Rebecca S. Holmes, Charles D. Blanke, Stephen R. Smalley, Özge Altug-Teber, Heinz-Josef Lenz, Adetunji T. Toriola, Jacqueline Benedetti, Cathryn Rankin, Karen W. Makar, Cornelia M. Ulrich
Publikováno v:
Cancer. 120:3329-3337
BACKGROUND Recurrence and toxicity occur commonly among patients with rectal cancer who are treated with 5-fluorouracil (5-FU). The authors hypothesized that genetic variation in folate-metabolizing genes could play a role in interindividual variabil
Autor:
Daniel G. Haller, Bryan Goldman, J. Milburn Jessup, Charles D. Blanke, Grant N. Stemmermann, Scott A. Hundahl, Stephen R. Smalley, John S. Macdonald, Jaffer A. Ajani, James A. Martenson, Jacqueline Benedetti, Leonard L. Gunderson, Norman C. Estes
Publikováno v:
Journal of Clinical Oncology. 30:2327-2333
Purpose Surgical resection of gastric cancer has produced suboptimal survival despite multiple randomized trials that used postoperative chemotherapy or more aggressive surgical procedures. We performed a randomized phase III trial of postoperative r
Autor:
Donald P. Quick, T. J. O'Rourke, James R. Faulkner, Mark J. Noble, Geoffrey R. Weiss, Stephen R. Smalley, Ronald L. Stephens, Ian M. Thompson, E. David Crawford, Gregory P. Swanson
Publikováno v:
Journal of Urology. 176:548-553
Radiation is considered the standard treatment for locally advanced (T3 and T4) prostate cancer but cure with radiation alone is infrequent. Studies have shown that adding androgen ablation improves the results but there is still much room for improv
Autor:
David Raben, Raymond E. Meyn, Laurie E. Gaspar, Paul Okunieff, Charles R. Thomas, Robert S. Lavey, Shankar Giri, Gregory P. Swanson, Beverly A. Teicher, Andrew T. Turrisi, Stephen R. Smalley
Publikováno v:
American Journal of Clinical Oncology. 26:522-529
To achieve the ultimate goal of cancer treatment, which is 100% cancer control with negligible toxicity, the therapeutic window must be enlarged, allowing for higher doses of beneficial treatments with reduced toxicity. The advent of image- and metab
Autor:
Leonard L. Gunderson, Tyvin A. Rich, James A. Martenson, Christopher G. Willett, Stephen R. Smalley, Bruce D. Minsky, Joel E. Tepper
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 52:283-293
Radiation therapy has recently emerged as a pivotal modality in the management of completely resected, high-risk gastric cancer. The recently published results of the Intergroup 0116 Gastric Surgical Adjuvant Trial randomized high-risk (T3,4 and/or n
Autor:
Cornelia M, Ulrich, Cathryn, Rankin, Adetunji T, Toriola, Karen W, Makar, Özge, Altug-Teber, Jacqueline K, Benedetti, Rebecca S, Holmes, Stephen R, Smalley, Charles D, Blanke, Heinz-Josef, Lenz
Publikováno v:
Cancer. 120(21)
Recurrence and toxicity occur commonly among patients with rectal cancer who are treated with 5-fluorouracil (5-FU). The authors hypothesized that genetic variation in folate-metabolizing genes could play a role in interindividual variability. The ob