Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Stephen Q Wong"'
Autor:
Andjelija Zivanovic Bujak, Chen-Fang Weng, Maria João Silva, Miriam Yeung, Louisa Lo, Sarah Ftouni, Cassandra Litchfield, Yi-An Ko, Keilly Kuykhoven, Courtney Van Geelen, Sushma Chandrashekar, Mark A Dawson, Sherene Loi, Stephen Q Wong, Sarah-Jane Dawson
Publikováno v:
PLoS Medicine, Vol 17, Iss 10, p e1003363 (2020)
BackgroundMetastatic breast cancer (mBC) is a heterogenous disease with increasing availability of targeted therapies as well as emerging genomic markers of therapeutic resistance, necessitating timely and accurate molecular characterization of disea
Externí odkaz:
https://doaj.org/article/400cac0c048b46efa33e37a54f2ee850
Autor:
Lavinia Tan, Chris Brown, Antony Mersiades, Chee Khoon Lee, Thomas John, Steven Kao, Genni Newnham, Kenneth O’Byrne, Sagun Parakh, Victoria Bray, Kevin Jasas, Sonia Yip, Stephen Q. Wong, Sarah Ftouni, Jerick Guinto, Sushma Chandrashekar, Stephen Clarke, Nick Pavlakis, Martin R. Stockler, Sarah-Jane Dawson, Benjamin J. Solomon
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract In this phase II, single arm trial (ACTRN12617000720314), we investigate if alternating osimertinib and gefitinib would delay the development of resistance to osimertinib in advanced, non-small cell lung cancer (NSCLC) with the epidermal gro
Externí odkaz:
https://doaj.org/article/2aee772d175142968edb2117d86331be
Autor:
Jason Li, Maria A Doyle, Isaam Saeed, Stephen Q Wong, Victoria Mar, David L Goode, Franco Caramia, Ken Doig, Georgina L Ryland, Ella R Thompson, Sally M Hunter, Saman K Halgamuge, Jason Ellul, Alexander Dobrovic, Ian G Campbell, Anthony T Papenfuss, Grant A McArthur, Richard W Tothill
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95217 (2014)
Targeted resequencing by massively parallel sequencing has become an effective and affordable way to survey small to large portions of the genome for genetic variation. Despite the rapid development in open source software for analysis of such data,
Externí odkaz:
https://doaj.org/article/3d45a5add0ba4d12b9f581db0214658a
Autor:
Lavinia Tan, Ben Tran, Jeanne Tie, Ben Markman, Sumi Ananda, Niall C. Tebbutt, Michael Michael, Emma Link, Stephen Q. Wong, Sushma Chandrashekar, Jerick Guinto, David Ritchie, Rachel Koldej, Benjamin J. Solomon, Grant A. McArthur, Rodney J. Hicks, Peter Gibbs, Sarah-Jane Dawson, Jayesh Desai
Publikováno v:
Clinical Cancer Research. 29:1017-1030
Purpose:BRAF V600E mutant metastatic colorectal cancer represents a significant clinical problem, with combination approaches being developed clinically with oral BRAF inhibitors combined with EGFR-targeting antibodies. While compelling preclinical d
Autor:
Rainier Arnolda, Kerryn Howlett, Timmy Chan, Jeanette Raleigh, Athena Hatzimihalis, Anthony Bell, Andrew Fellowes, Shahneen Sandhu, Grant A. McArthur, Stephen B. Fox, Sarah-Jane Dawson, Chelsee Hewitt, Kate Jones, Stephen Q. Wong
Publikováno v:
Pathology. 54:772-778
Droplet digital PCR (ddPCR) has been demonstrated in many research studies to be a sensitive method in the analysis of circulating tumour DNA (ctDNA) for identifying mutations and tracking disease. The transition of ddPCR into the diagnostic setting
Autor:
Andreas Behren, Ralf B. Schittenhelm, Anthony W. Purcell, Jonathan S. Cebon, Rochelle Ayala, Chen Li, Nathan P. Croft, Terry C.C. Lim Kam Sian, Sri H. Ramarathinam, Weisan Chen, Stephen Q. Wong, Divya Duscharla, Ritchlynn Aranha, Cyril Deceneux, Simone Ostrouska, Katherine Woods, Pouya Faridi
Table S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101dc697972aa21525bd453c74ac4c1c
https://doi.org/10.1158/2326-6066.22542564
https://doi.org/10.1158/2326-6066.22542564
Autor:
Andreas Behren, Ralf B. Schittenhelm, Anthony W. Purcell, Jonathan S. Cebon, Rochelle Ayala, Chen Li, Nathan P. Croft, Terry C.C. Lim Kam Sian, Sri H. Ramarathinam, Weisan Chen, Stephen Q. Wong, Divya Duscharla, Ritchlynn Aranha, Cyril Deceneux, Simone Ostrouska, Katherine Woods, Pouya Faridi
Supplementary Figures S1-S10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e69eec6136b37c9b1a336e5024908c3
https://doi.org/10.1158/2326-6066.22542573
https://doi.org/10.1158/2326-6066.22542573
Autor:
Andreas Behren, Ralf B. Schittenhelm, Anthony W. Purcell, Jonathan S. Cebon, Rochelle Ayala, Chen Li, Nathan P. Croft, Terry C.C. Lim Kam Sian, Sri H. Ramarathinam, Weisan Chen, Stephen Q. Wong, Divya Duscharla, Ritchlynn Aranha, Cyril Deceneux, Simone Ostrouska, Katherine Woods, Pouya Faridi
Antigen recognition by CD8+ T cells is governed by the pool of peptide antigens presented on the cell surface in the context of HLA class I complexes. Studies have shown not only a high degree of plasticity in the immunopeptidome, but also that a con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7581bef57082293b06b3b1e8f96f5d26
https://doi.org/10.1158/2326-6066.c.6549978.v1
https://doi.org/10.1158/2326-6066.c.6549978.v1
Autor:
Jayesh Desai, Sarah-Jane Dawson, Peter Gibbs, Rodney J. Hicks, Grant A. McArthur, Benjamin J. Solomon, Rachel Koldej, David Ritchie, Jerick Guinto, Sushma Chandrashekar, Stephen Q. Wong, Emma Link, Michael Michael, Niall C. Tebbutt, Sumi Ananda, Ben Markman, Jeanne Tie, Ben Tran, Lavinia Tan
Supplementary material
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17cf0691eb04b9f3deacdfda3c5cc17f
https://doi.org/10.1158/1078-0432.22490194.v1
https://doi.org/10.1158/1078-0432.22490194.v1
Autor:
Helen Rizos, Georgina V. Long, Richard A. Scolyer, Stephen Q. Wong, Elin S. Gray, Thien Tra, Zeyad Al-Ogaili, Michael J. Millward, Richard F. Kefford, Sarah-Jane Dawson, Russell J. Diefenbach, Alison M. Weppler, Shahneen Sandhu, Ashleigh C. McEvoy, Matteo S. Carlino, Alexander M. Menzies, Jenny H. Lee
Supplementary Figure 1. Flow chart of patient selection. Supplementary Figure 2. Flowchart of patients with disease response assessment available (n = 57).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4292d69430eaf828060744de34bf6411
https://doi.org/10.1158/1078-0432.22477832.v1
https://doi.org/10.1158/1078-0432.22477832.v1