Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Stephen Pick"'
Autor:
Stephen M. Moore, James D. Quirk, Andrew W. Lassiter, Richard Laforest, Gregory D. Ayers, Cristian T. Badea, Andriy Y. Fedorov, Paul E. Kinahan, Matthew Holbrook, Peder E. Z. Larson, Renuka Sriram, Thomas L. Chenevert, Dariya Malyarenko, John Kurhanewicz, A. McGarry Houghton, Brian D. Ross, Stephen Pickup, James C. Gee, Rong Zhou, Seth T. Gammon, Henry Charles Manning, Raheleh Roudi, Heike E. Daldrup-Link, Michael T. Lewis, Daniel L. Rubin, Thomas E. Yankeelov, Kooresh I. Shoghi
Publikováno v:
Tomography, Vol 9, Iss 3, Pp 995-1009 (2023)
Preclinical imaging is a critical component in translational research with significant complexities in workflow and site differences in deployment. Importantly, the National Cancer Institute’s (NCI) precision medicine initiative emphasizes the use
Externí odkaz:
https://doaj.org/article/c03b45b43e1546d4a22efc4f2e820217
Autor:
Seth T. Gammon, Allison S. Cohen, Adrienne L. Lehnert, Daniel C. Sullivan, Dariya Malyarenko, Henry Charles Manning, David A. Hormuth, Heike E. Daldrup-Link, Hongyu An, James D. Quirk, Kooresh Shoghi, Mark David Pagel, Paul E. Kinahan, Robert S. Miyaoka, A. McGarry Houghton, Michael T. Lewis, Peder Larson, Renuka Sriram, Stephanie J. Blocker, Stephen Pickup, Alexandra Badea, Cristian T. Badea, Thomas E. Yankeelov, Thomas L. Chenevert
Publikováno v:
Tomography, Vol 9, Iss 2, Pp 750-758 (2023)
Providing method descriptions that are more detailed than currently available in typical peer reviewed journals has been identified as an actionable area for improvement. In the biochemical and cell biology space, this need has been met through the c
Externí odkaz:
https://doaj.org/article/987d12f93c464f0385e654e3a94d2678
Autor:
Dariya Malyarenko, Ghoncheh Amouzandeh, Stephen Pickup, Rong Zhou, Henry Charles Manning, Seth T. Gammon, Kooresh I. Shoghi, James D. Quirk, Renuka Sriram, Peder Larson, Michael T. Lewis, Robia G. Pautler, Paul E. Kinahan, Mark Muzi, Thomas L. Chenevert
Publikováno v:
Tomography, Vol 9, Iss 1, Pp 375-386 (2023)
Relevant to co-clinical trials, the goal of this work was to assess repeatability, reproducibility, and bias of the apparent diffusion coefficient (ADC) for preclinical MRIs using standardized procedures for comparison to performance of clinical MRIs
Externí odkaz:
https://doaj.org/article/9222f4abb7d4458ca75182c703cf97ac
Publikováno v:
Tomography, Vol 8, Iss 5, Pp 2113-2128 (2022)
Application of quantitative dynamic contrast-enhanced (DCE) MRI in mouse models of abdominal cancer is challenging due to the effects of RF inhomogeneity, image corruption from rapid respiratory motion and the need for high spatial and temporal resol
Externí odkaz:
https://doaj.org/article/d6c7c372770b4720a3d239e20bd678b9
Autor:
Jean M. Williams, James M. Trzaskos, Robert A. Copeland, Stephen Pick, Sherrill Nurnberg, John V. Giannaras, Donald J. P. Pinto, Maryanne B. Covington
Publikováno v:
Proceedings of the National Academy of Sciences. 91:11202-11206
Selective inhibition of the inducible isoform of prostaglandin G/H synthase (cyclooxygenase-2; COX2; EC 1.14.99.1) can be achieved with compounds of the general form of aryl methyl sulfonyls and aryl methyl sulfonamides. DuP 697 and NS-398 are repres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1345382814ca74dae8b53a007274c739
https://doi.org/10.1073/pnas.91.23.11202
https://doi.org/10.1073/pnas.91.23.11202
Autor:
Jianbo Cao, Hee Kwon Song, Hanwen Yang, Victor Castillo, Jinbo Chen, Cynthia Clendenin, Mark Rosen, Rong Zhou, Stephen Pickup
Publikováno v:
Tomography, Vol 7, Iss 1, Pp 66-79 (2021)
Respiratory motion and increased susceptibility effects at high magnetic fields pose challenges for quantitative diffusion-weighted MRI (DWI) of a mouse abdomen on preclinical MRI systems. We demonstrate the first application of radial k-space-sample
Externí odkaz:
https://doaj.org/article/4c5eabd3c7aa4dc78f179b57a313ca68
Autor:
Ana A. Folgueiras-Amador, Katie E. Jolley, Peter R. Birkin, Richard C.D. Brown, Derek Pletcher, Stephen Pickering, Medhat Sharabi, Oscar de Frutos, Carlos Mateos, Juan A. Rincón
Publikováno v:
Electrochemistry Communications, Vol 100, Iss , Pp 6-10 (2019)
It is demonstrated that the addition of a non-ionic surfactant (Triton X-100 or Brij L23) to the electrolyte medium leads to a significant improvement to the current efficiency for the methoxylation of N-formylpyrrolidine in a flow electrolysis cell
Externí odkaz:
https://doaj.org/article/a52aadf3b9774043aac1482fc720b312
Autor:
Brendan T Keenan, Jeanette C Webster, Andrew S Wiemken, Nir Lavi-Romer, Teresa Nguyen, Karen L Svenson, Raymond J Galante, Gary A Churchill, Stephen Pickup, Allan I Pack, Richard J Schwab
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 5 (2021)
AbstractSpecific fat distributions are risk factors for complex diseases, including coronary heart disease and obstructive sleep apnea. To demonstrate the utility of high-diversity mouse models for elucidating genetic associations, we describe the ph
Externí odkaz:
https://doaj.org/article/8e2a8efc71d0473aa389813b8f957db8
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Magnetic field effects can provide a handle on steering chemical reactions and manipulating yields. The presence of a magnetic field can influence the energy levels of the active species by interacting with their spin states. Here we demonstrate the
Externí odkaz:
https://doaj.org/article/4102731bb22d4f31895b61019d0ecfcf
Autor:
Junning Yang, Claire Simonneau, Robert Kilker, Laura Oakley, Matthew D Byrne, Zuzana Nichtova, Ioana Stefanescu, Fnu Pardeep‐Kumar, Sushil Tripathi, Eric Londin, Pascale Saugier‐Veber, Belinda Willard, Mathew Thakur, Stephen Pickup, Hiroshi Ishikawa, Horst Schroten, Richard Smeyne, Arie Horowitz
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 1, Pp 1-19 (2018)
Abstract Though congenital hydrocephalus is heritable, it has been linked only to eight genes, one of which is MPDZ. Humans and mice that carry a truncated version of MPDZ incur severe hydrocephalus resulting in acute morbidity and lethality. We show
Externí odkaz:
https://doaj.org/article/9e7dfd6574c64708bffe246dee632cbb