Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Stephen Philip Jackson"'
Autor:
Felipe Cortés Ledesma, Yukihide Tomari, Stephen Philip Jackson, Pablo Huertas, Sandra Muñoz-Galván, Ana López Saavedra, Andres Aguilera
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research; Vol 41
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Digital.CSIC. Repositorio Institucional del CSIC
Nucleic Acids Research; Vol 41
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Digital.CSIC. Repositorio Institucional del CSIC
While regulating the choice between homologous recombination and non-homologous end joining (NHEJ) as mechanisms of double-strand break (DSB) repair is exerted at several steps, the key step is DNA end resection, which in Saccharomyces cerevisiae is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4753292d9e5578f3367b344fd5fa8c3a
Publikováno v:
Europe PubMed Central
The DNA-dependent protein kinase (DNA-PK) is a serine/threonine protein kinase that is involved in mammalian DNA double-strand break repair. The catalytic subunit of DNA-PK (DNA-PKcs) shares sequence homology in its kinase domain with phosphatidylino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0d8da705d0dd4e2de68c347b877bca82
https://pubmed.ncbi.nlm.nih.gov/10363977
https://pubmed.ncbi.nlm.nih.gov/10363977
Publikováno v:
Europe PubMed Central
The DNA-dependent protein kinase (DNA-PK) is a nuclear protein serine/threonine kinase that must bind to DNA double-strand breaks to be active. We and others have shown that it is a multiprotein complex comprising an approx. 465 kDa catalytic subunit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b22f96076f6c87332cf30071987f5f52
https://pubmed.ncbi.nlm.nih.gov/10207623
https://pubmed.ncbi.nlm.nih.gov/10207623
Publikováno v:
Europe PubMed Central
Ataxia telangiectasia (A-T) is a human disorder that results in a number of clinical symptoms, including cerebellar degeneration and increased cancer predisposition. Recently the gene that is defective in A-T has been cloned and designated ATM. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::61e41252820823cc2615ae24d39c720a
https://pubmed.ncbi.nlm.nih.gov/9000145
https://pubmed.ncbi.nlm.nih.gov/9000145
Autor:
Song Q, Sp, Lees-Miller, Kumar S, Zhang Z, Dw, Chan, Gc, Smith, Stephen Philip Jackson, Es, Alnemri, Litwack G, Kk, Khanna, Mf, Lavin
Publikováno v:
Europe PubMed Central
Radiosensitive cell lines derived from X-ray cross complementing group 5 (XRCC5), SCID mice and a human glioma cell line lack components of the DNA-dependent protein kinase, DNA-PK, suggesting that DNA-PK plays an important role in DNA double-strand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::afd395f39ae75d2b3c6b21eb6cb9c394
http://europepmc.org/abstract/med/8670824
http://europepmc.org/abstract/med/8670824
Publikováno v:
Europe PubMed Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3b00b07bc6f92a9bdb77c5b69a9627b8
http://europepmc.org/abstract/med/8787619
http://europepmc.org/abstract/med/8787619
Publikováno v:
Europe PubMed Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4ad3da210ea61c84f03385e5bce2b472
http://europepmc.org/abstract/med/15611643
http://europepmc.org/abstract/med/15611643
Publikováno v:
Europe PubMed Central
The DNA-dependent protein kinase (DNA-PK), whose catalytic subunit shows structural similarities to the Ataxia telangiectasia (AT) gene product (ATM), has also been implicated in the p53-mediated signal transduction pathway that activates the cellula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::eba6ca73b3fe94a1289b8d7597dc45df
http://europepmc.org/abstract/med/8808686
http://europepmc.org/abstract/med/8808686