Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Stephen P.G. Moore"'
Autor:
Deborah Lang, Jag Bhawan, Candice Brem, Adil J. Haresi, Sixia Xiao, Elizabeth C. Little, Stephen P.G. Moore, Jason W. Lui, Jennifer La, Yougang Zhai, Lee Huang
Supplementary data and methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12e58d950cd92320d21e2fe8f276fc85
https://doi.org/10.1158/0008-5472.22425945.v1
https://doi.org/10.1158/0008-5472.22425945.v1
Autor:
Deborah Lang, Jag Bhawan, Candice Brem, Adil J. Haresi, Sixia Xiao, Elizabeth C. Little, Stephen P.G. Moore, Jason W. Lui, Jennifer La, Yougang Zhai, Lee Huang
The failure of once promising target-specific therapeutic strategies often arises from redundancies in gene expression pathways. Even with new melanoma treatments, many patients are not responsive or develop resistance, leading to disease progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35c053a03864aad412562ba7b59ffe3a
https://doi.org/10.1158/0008-5472.c.6512190.v1
https://doi.org/10.1158/0008-5472.c.6512190.v1
Autor:
Deborah Lang, Jag Bhawan, Candice Brem, Adil J. Haresi, Sixia Xiao, Elizabeth C. Little, Stephen P.G. Moore, Jason W. Lui, Jennifer La, Yougang Zhai, Lee Huang
Supplementary figures S1, S2, and S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fcf14f05c2b3760889a26c097410d4e
https://doi.org/10.1158/0008-5472.22425942.v1
https://doi.org/10.1158/0008-5472.22425942.v1
Autor:
Sixia Xiao, Jennifer La, Lee Huang, Stephen P.G. Moore, Jag Bhawan, Jason W Lui, Elizabeth C. Little, Deborah Lang, Candice E. Brem, Yougang Zhai, Adil J Haresi
Publikováno v:
Cancer Res
The failure of once promising target-specific therapeutic strategies often arises from redundancies in gene expression pathways. Even with new melanoma treatments, many patients are not responsive or develop resistance, leading to disease progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2d8997dd53ae2ec8a70bd44a8111c0e
https://doi.org/10.1158/0008-5472.can-19-1668
https://doi.org/10.1158/0008-5472.can-19-1668
Publikováno v:
Pigment Cell Melanoma Res
Yes Associated Protein 1 (YAP) and Transcriptional coactivator with PDZ-Binding Motif (TAZ) are transcriptional coactivators that have been implicated in driving metastasis and progression in many cancers, mainly through their transcriptional regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::432489058ac7798d1e75f92eddffb90e
https://europepmc.org/articles/PMC8958630/
https://europepmc.org/articles/PMC8958630/
Publikováno v:
DNA Repair. 12:1152-1158
CREB controls ∼25% of the mammalian transcriptome. Small changes in binding to its consensus (CRE) sequence are likely to be amplified many fold in initiating transcription. Here we show that DNA lesions repaired by the base excision repair (BER) p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c65534e512c6288ef6ff597a3c38efca
https://doi.org/10.1016/j.dnarep.2013.10.002
https://doi.org/10.1016/j.dnarep.2013.10.002
Transcriptional regulation is a tightly regulated, vital process. The transcription factor cyclic AMP-response element-binding protein 1 (CREB1) controls ∼25% of the mammalian transcriptome by binding the CREB1 binding site consensus sequence (CRE)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0a26d155bcbefc5c3652f0c16e47815
https://europepmc.org/articles/PMC4786688/
https://europepmc.org/articles/PMC4786688/
Publikováno v:
The FASEB Journal. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a0c5fb22bb5921ee9bdf43490c1f1ba
https://doi.org/10.1096/fasebj.29.1_supplement.878.8
https://doi.org/10.1096/fasebj.29.1_supplement.878.8
Autor:
John Boyer, Patrick G. Johnston, Estelle McLean, Andrea McCulla, Wendy L. Allen, Carlos Caldas, Peter M. Wilson, Daniel B. Longley, Stephen P.G. Moore
Publikováno v:
Cancer Research. 66:2765-2777
DNA microarray analysis was used to analyze the transcriptional profile of HCT116 colorectal cancer cells that were treated with 5-fluorouracil (5-FU) or oxaliplatin and selected for resistance to these agents. Bioinformatic analyses identified sets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c30d5befb78eb52accaa6b140a9bd513
https://doi.org/10.1158/0008-5472.can-05-2693
https://doi.org/10.1158/0008-5472.can-05-2693
Publikováno v:
Journal of Biological Chemistry. 276:23322-23328
Generation of the amyloid peptide through proteolytic processing of the amyloid precursor protein by beta- and gamma-secretases is central to the etiology of Alzheimer's disease. The highly elusive beta-secretase was recently identified as a transmem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb36899564eb47e5a055fb676b255377
https://doi.org/10.1074/jbc.m101069200
https://doi.org/10.1074/jbc.m101069200