Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Stephen P. Fox"'
Autor:
Tamsin J. Robb, Yinan Liu, Braden Woodhouse, Charlotta Windahl, Daniel Hurley, Grant McArthur, Stephen B. Fox, Lisa Brown, Parry Guilford, Alice Minhinnick, Christopher Jackson, Cherie Blenkiron, Kate Parker, Kimiora Henare, Rose McColl, Bianca Haux, Nick Young, Veronica Boyle, Laird Cameron, Sanjeev Deva, Jane Reeve, Cristin G. Print, Michael Davis, Uwe Rieger, Ben Lawrence
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-6 (2024)
Abstract We introduce a proof-of-concept extended reality (XR) environment for discussing cancer, presenting genomic information from multiple tumour sites in the context of 3D tumour models generated from CT scans. This tool enhances multidisciplina
Externí odkaz:
https://doaj.org/article/ed44e8f216c04158b220078ef64c705e
Autor:
Tanjina Kader, Elena Provenzano, Madawa W. Jayawardana, Shona Hendry, Jia-Min Pang, Kenneth Elder, David J. Byrne, Lauren Tjoeka, Helen ML. Frazer, Eloise House, Sureshni I. Jayasinghe, Holly Keane, Anand Murugasu, Neeha Rajan, Islam M. Miligy, Michael Toss, Andrew R. Green, Emad A. Rakha, Stephen B. Fox, G. Bruce Mann, Ian G. Campbell, Kylie L. Gorringe
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-10 (2024)
Abstract Various histopathological, clinical and imaging parameters have been evaluated to identify a subset of women diagnosed with lesions with uncertain malignant potential (B3 or BIRADS 3/4A lesions) who could safely be observed rather than being
Externí odkaz:
https://doaj.org/article/b48a3f6e9ea54a189ccefd102db6473b
Autor:
W. F. Drew Bennett, Austen Bernardi, Tugba Nur Ozturk, Helgi I. Ingólfsson, Stephen J. Fox, Delin Sun, C. Mark Maupin
Publikováno v:
Molecules, Vol 29, Iss 15, p 3557 (2024)
Soft condensed matter is challenging to study due to the vast time and length scales that are necessary to accurately represent complex systems and capture their underlying physics. Multiscale simulations are necessary to study processes that have di
Externí odkaz:
https://doaj.org/article/8afa60ac7c714138b7c055b802866d5c
Autor:
Elena A. Takano, Melissa M. Younes, Katie Meehan, Lisa Spalding, Max Yan, Prue Allan, Stephen B. Fox, Andy Redfern, David Clouston, Graham G. Giles, Elizabeth L. Christie, Robin L. Anderson, Magnus Zethoven, Kelly-Anne Phillips, Kylie Gorringe, Kara L. Britt
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Triple negative BCa (TNBC) is defined by a lack of expression of estrogen (ERα), progesterone (PgR) receptors and human epidermal growth factor receptor 2 (HER2) as assessed by protein expression and/or gene amplification. It mak
Externí odkaz:
https://doaj.org/article/8425c7a02adc4bc79190c37d150123d5
Autor:
Genevieve Dall, Cassandra J. Vandenberg, Ksenija Nesic, Gayanie Ratnayake, Wenying Zhu, Joseph H. A. Vissers, Justin Bedő, Jocelyn Penington, Matthew J. Wakefield, Damien Kee, Amandine Carmagnac, Ratana Lim, Kristy Shield-Artin, Briony Milesi, Amanda Lobley, Elizabeth L. Kyran, Emily O’Grady, Joshua Tram, Warren Zhou, Devindee Nugawela, Kym Pham Stewart, Reece Caldwell, Lia Papadopoulos, Ashley P. Ng, Alexander Dobrovic, Stephen B. Fox, Orla McNally, Jeremy D. Power, Tarek Meniawy, Teng Han Tan, Ian M. Collins, Oliver Klein, Stephen Barnett, Inger Olesen, Anne Hamilton, Oliver Hofmann, Sean Grimmond, Anthony T. Papenfuss, Clare L. Scott, Holly E. Barker
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-20 (2023)
Abstract Background Uterine leiomyosarcoma (uLMS) is a rare and aggressive gynaecological malignancy, with individuals with advanced uLMS having a five-year survival of 0.2) but only two samples had a CHORD score > 50%, one of which had a homozygous
Externí odkaz:
https://doaj.org/article/90697e9e0fe04ca583a35a4167337ba8
Autor:
Javier Octavio Mejía-Hernández, Simon P. Keam, Reem Saleh, Fenella Muntz, Stephen B. Fox, David Byrne, Arielle Kogan, Lokman Pang, Jennifer Huynh, Cassandra Litchfield, Franco Caramia, Guillermina Lozano, Hua He, James M. You, Shahneen Sandhu, Scott G. Williams, Ygal Haupt, Sue Haupt
Publikováno v:
Cell Death and Disease, Vol 13, Iss 9, Pp 1-17 (2022)
Abstract Understanding prostate cancer onset and progression in order to rationally treat this disease has been critically limited by a dire lack of relevant pre-clinical animal models. We have generated a set of genetically engineered mice that mimi
Externí odkaz:
https://doaj.org/article/72de5aef0f664a85b0c01a44bc290580
Autor:
Kenneth D. Doig, Christopher G. Love, Thomas Conway, Andrei Seleznev, David Ma, Andrew Fellowes, Piers Blombery, Stephen B. Fox
Publikováno v:
BMC Medical Genomics, Vol 15, Iss 1, Pp 1-12 (2022)
Abstract Background Next generation sequencing for oncology patient management is now routine in clinical pathology laboratories. Although wet lab, sequencing and pipeline tasks are largely automated, the analysis of variants for clinical reporting r
Externí odkaz:
https://doaj.org/article/9adcc47954bd489dbac88173e5089a37
Autor:
Madhu Singh, Linda Mileshkin, Penelope Schofield, Bo Gao, Gary Richardson, Andrew Pattison, Rodney J Hicks, Niko Thio, Mark Warren, Colin Wood, Stephen B Fox, Anna DeFazio, Andrew Fellowes, Christopher Steer, David Bowtell, Nicholas Wilcken, Tharani Sivakumaran, Atara Posner, Dariush Etemadmoghadam, Krista Fisher, Samantha Webb, Christos S Karapetis, Ian M Collins, Narayan Karanth, Owen W J Prall, Richard William Tothill
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 1 (2023)
Background Cancer of unknown primary (CUP) is a heterogeneous group of metastatic cancers where a primary tissue of origin (TOO) is uncertain. Most patients with CUP have limited treatment options and poor survival outcomes. Immune checkpoint inhibit
Externí odkaz:
https://doaj.org/article/62a3f3bb406f4f688c1bd4d184af4202
In vitro and in vivo drug screens of tumor cells identify novel therapies for high‐risk child cancer
Autor:
Loretta M S Lau, Chelsea Mayoh, Jinhan Xie, Paulette Barahona, Karen L MacKenzie, Marie Wong, Alvin Kamili, Maria Tsoli, Tim W Failes, Amit Kumar, Emily V A Mould, Andrew Gifford, Shu‐Oi Chow, Mark Pinese, Jamie I Fletcher, Greg M Arndt, Dong‐Anh Khuong‐Quang, Carol Wadham, Daniel Batey, Georgina Eden, Peter Trebilcock, Swapna Joshi, Stephanie Alfred, Anjana Gopalakrishnan, Aaminah Khan, Dylan Grebert Wade, Patrick A Strong, Elodie Manouvrier, Lisa T Morgan, Miriam Span, Jin Yi Lim, Roxanne Cadiz, Caitlin Ung, David M Thomas, Katherine M Tucker, Meera Warby, Geoffrey B McCowage, Luciano Dalla‐Pozza, Jennifer A Byrne, Federica Saletta, Andrew Fellowes, Stephen B Fox, Murray D Norris, Vanessa Tyrrell, Toby N Trahair, Richard B Lock, Mark J Cowley, Paul G Ekert, Michelle Haber, David S Ziegler, Glenn M Marshall
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 4, Pp 1-15 (2021)
Abstract Biomarkers which better match anticancer drugs with cancer driver genes hold the promise of improved clinical responses and cure rates. We developed a precision medicine platform of rapid high‐throughput drug screening (HTS) and patient‐
Externí odkaz:
https://doaj.org/article/f2db646d5831450d847f4d18a36cdea2
Autor:
Courtney T. van Geelen, Peter Savas, Zhi Ling Teo, Stephen J. Luen, Chen-Fang Weng, Yi-An Ko, Keilly S. Kuykhoven, Franco Caramia, Roberto Salgado, Prudence A. Francis, Sarah-Jane Dawson, Stephen B. Fox, Andrew Fellowes, Sherene Loi
Publikováno v:
Breast Cancer Research, Vol 24, Iss 1, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/cb99f00f69a94e658b278335ef236f7b