Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Stephen P Saville"'
Autor:
Ashok K Chaturvedi, Anna L Lazzell, Stephen P Saville, Floyd L Wormley, Carlos Monteagudo, Jose L Lopez-Ribot
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20449 (2011)
Understanding the pathogenesis of infectious disease requires the examination and successful integration of parameters related to both microbial virulence and host responses. As a practical and powerful method to control microbial gene expression, in
Externí odkaz:
https://doaj.org/article/3bb94cde87fd46d4988ff9c45b72af73
Autor:
Sandra M. Cardona, Sangwon V. Kim, Kaira A. Church, Vanessa O. Torres, Ian A. Cleary, Andrew S. Mendiola, Stephen P. Saville, Stephanie S. Watowich, Jan Parker-Thornburg, Alejandro Soto-Ospina, Pedronel Araque, Richard M. Ransohoff, Astrid E. Cardona
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Multiple sclerosis (MS), an inflammatory demyelinating disease of the central nervous system (CNS) is the leading cause of non-traumatic neurological disability in young adults. Immune mediated destruction of myelin and oligodendrocytes is considered
Externí odkaz:
https://doaj.org/article/76a2d98136d74fc3b8f720a970c7379d
Autor:
Jesus A. Romo, Christopher G. Pierce, Marisol Esqueda, Chiung-Yu Hung, Stephen. P. Saville, Jose L. Lopez-Ribot
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
We have previously identified a small molecule compound, N-[3-(allyloxy)-phenyl]-4-methoxybenzamide (9029936), that exerts potent inhibitory activity against filamentation and biofilm formation by the Candida albicans SC5314 strain and represents a l
Externí odkaz:
https://doaj.org/article/d778c1bfd740470587eb7f7dbbd37c03
Publikováno v:
Journal of Fungi, Vol 5, Iss 1, p 22 (2019)
Angiogenesis mediated by proteins such as Fibroblast Growth Factor-2 (FGF-2) is a vital component of normal physiological processes and has also been implicated in contributing to the disease state associated with various microbial infections. Previo
Externí odkaz:
https://doaj.org/article/991e0749770b46d081dea9ac93871902
Autor:
Ian A. Cleary, Stephen P. Saville
Publikováno v:
Mycopathologia. 186:103-107
In Candida albicans, geldanamycin treatment inhibits the essential chaperone Hsp90 and induces a change from yeast to filamentous morphology, likely by impeding cell cycle progression and division. However, filaments formed by wild-type cells upon ge
Autor:
Stephen P, Saville, Ian A, Cleary
Publikováno v:
Mycopathologia. 186(1)
In Candida albicans, geldanamycin treatment inhibits the essential chaperone Hsp90 and induces a change from yeast to filamentous morphology, likely by impeding cell cycle progression and division. However, filaments formed by wild-type cells upon ge
Autor:
Hong Cai, Jose L. Lopez-Ribot, Hao Zhang, Stephen P. Saville, Yufeng Wang, Julia Koehler, Jesus A. Romo, David Kadosh
Publikováno v:
mSphere, Vol 4, Iss 5 (2019)
mSphere
mSphere, Vol 4, Iss 5, p e00620-19 (2019)
mSphere
mSphere, Vol 4, Iss 5, p e00620-19 (2019)
These results from whole-genome transcriptional profiling provide further insights into the biological activity and mode of action of a small-molecule inhibitor of C. albicans filamentation. This information will assist in the development of novel an
Publikováno v:
mBio
mBio, Vol 10, Iss 3, p e01179-19 (2019)
mBio, Vol 10, Iss 3, p e01179-19 (2019)
Microbial communities have a great impact in health and disease. C. albicans interacts with multiple microorganisms in the oral cavity, frequently forming polymicrobial biofilms. We report on the synergistic interactions between C. albicans and the G
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
Fungal and bacterial populations coexist in the oral cavity, frequently forming mixed-species biofilms that complicate treatment against polymicrobial infections. However, despite relevance to oral health, the bidirectional interactions between these
Autor:
Jesus A. Romo, Christopher G. Pierce, Ashok K. Chaturvedi, Stephen P. Saville, Jose L. Lopez-Ribot
Publikováno v:
Frontiers for Young Minds. 7