Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Stephen P Matthews"'
Autor:
Lee A Armstrong, Sven M Lange, Virginia Dee Cesare, Stephen P Matthews, Raja Sekhar Nirujogi, Isobel Cole, Anthony Hope, Fraser Cunningham, Rachel Toth, Rukmini Mukherjee, Denisa Bojkova, Franz Gruber, David Gray, Paul G Wyatt, Jindrich Cinatl, Ivan Dikic, Paul Davies, Yogesh Kulathu
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0253364 (2021)
Of the 16 non-structural proteins (Nsps) encoded by SARS CoV-2, Nsp3 is the largest and plays important roles in the viral life cycle. Being a large, multidomain, transmembrane protein, Nsp3 has been the most challenging Nsp to characterize. Encoded
Externí odkaz:
https://doaj.org/article/7e4e63d2ba344215bb01a64466ff2cc4
Publikováno v:
Heliyon, Vol 10, Iss 9, Pp e30207- (2024)
P-glycoprotein (P-gp) and Breast Cancer Resistance Protein (BCRP) multidrug resistance (MDR) transporters are localized at the luminal surface of the blood-brain barrier (BBB). They confer fetal brain protection against harmful compounds that may be
Externí odkaz:
https://doaj.org/article/688ecff3f64448daa6516d6e1fe942b5
Publikováno v:
RSF: The Russell Sage Foundation Journal of the Social Sciences, Vol 9, Iss 1, Pp 1-24 (2023)
Suburban inequality is the focus of this double issue of RSF: The Russell Sage Foundation Journal of the Social Sciences. This introduction addresses the limited related scholarship, describes how inequality unfolds differently in suburban communitie
Externí odkaz:
https://doaj.org/article/730e19d7c2804a1c9029eb7dde0cf8c2
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-17 (2023)
Abstract Background The multidrug resistance (MDR) transporters, P-glycoprotein (P-gp, encoded by ABCB1) and breast cancer resistance protein (BCRP/ABCG2) contribute to the blood–brain barrier (BBB), protecting the brain from drug exposure. The imp
Externí odkaz:
https://doaj.org/article/3da342e3dac943be899df30efd3c47f5
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT Human cytomegalovirus (HCMV) is a betaherpesvirus that establishes lifelong infection in its host and can cause severe comorbidities in individuals with suppressed or compromised immune systems. The lifecycle of HCMV consists of lytic and la
Externí odkaz:
https://doaj.org/article/1baa590fe0aa4c9890996d03c17d6e98
Autor:
Derrick Ssewanyana, PhD, Stephane L. Borque, PhD, Stephen J. Lye, PhD, Stephen G. Matthews, PhD
Publikováno v:
AJOG Global Reports, Vol 3, Iss 3, Pp 100222- (2023)
OBJECTIVE: This study evaluated the correlation between maternal hepcidin and other biomarkers of iron status, markers of inflammation, and maternal body weight during pregnancy, as well as neurodevelopment in the offspring. DATA SOURCES: PubMed, Web
Externí odkaz:
https://doaj.org/article/cc60b77251c348d29a98c60a0567da22
Autor:
Soheil Hashtarkhani, Stephen A. Matthews, Ping Yin, Alireza Mohammadi, Shahab MohammadEbrahimi, Mahmood Tara, Behzad Kiani
Publikováno v:
Geospatial Health, Vol 18, Iss 2 (2023)
This study integrates geographical information systems (GIS) with a mathematical optimization technique to enhance emergency medical services (EMS) coverage in a county in the northeast of Iran. EMS demand locations were determined through one-year E
Externí odkaz:
https://doaj.org/article/4284ae08e4bc4cab9b0aca7304a73d86
Publikováno v:
International Journal of Digital Earth, Vol 14, Iss 1, Pp 121-138 (2021)
Searching for a property is inherently a multicriteria spatial decision. The decision is primarily based on three high-level criteria composed of household needs, building facilities, and location characteristics. Location choice is driven by diverse
Externí odkaz:
https://doaj.org/article/5b071d91474840aab13521184d5aec5b
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Synthetic glucocorticoids (sGC) are administered to women at risk of preterm delivery, approximately 10% of all pregnancies. In animal models, offspring exposed to elevated glucocorticoids, either by administration of sGC or endogenous gluco
Externí odkaz:
https://doaj.org/article/a9f78b985a354861a1a8c4daa04ebdf4
Publikováno v:
Forest Ecosystems, Vol 8, Iss 1, Pp 1-14 (2021)
Abstract Background Mature oak (Quercus spp.) and hickory (Carya spp.) trees are gradually being replaced by more shade-tolerant tree species across the eastern U.S., likely due to fire suppression and increased precipitation. Oaks and hickories are
Externí odkaz:
https://doaj.org/article/4d0f0241c30d45d6a6d23b849f53adc1