Zobrazeno 1 - 10
of 361
pro vyhledávání: '"Stephen P Goff"'
Autor:
Shelby Winans, Stephen P Goff
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1009147 (2020)
The central function of the retroviral integrase protein (IN) is to catalyze the integration of viral DNA into the host genome to form the provirus. The IN protein has also been reported to play a role in a number of other processes throughout the re
Externí odkaz:
https://doaj.org/article/683eff356c794c6d9be273fd5452deb0
Autor:
Marisa A Yonemitsu, Rachael M Giersch, Maria Polo-Prieto, Maurine Hammel, Alexis Simon, Florencia Cremonte, Fernando T Avilés, Nicolás Merino-Véliz, Erika AV Burioli, Annette F Muttray, James Sherry, Carol Reinisch, Susan A Baldwin, Stephen P Goff, Maryline Houssin, Gloria Arriagada, Nuria Vázquez, Nicolas Bierne, Michael J Metzger
Publikováno v:
eLife, Vol 8 (2019)
Transmissible cancers, in which cancer cells themselves act as an infectious agent, have been identified in Tasmanian devils, dogs, and four bivalves. We investigated a disseminated neoplasia affecting geographically distant populations of two specie
Externí odkaz:
https://doaj.org/article/83ce2ef4949f4ee982360087df01c4a8
Autor:
Stephen P. Goff
Publikováno v:
Frontiers in Virology, Vol 4 (2024)
The unintegrated HIV-1 DNAs formed by reverse transcription in the early hours after infection are subject to profound transcriptional silencing. The repression of expression of foreign DNA, as an aspect of the innate immune system, serves to restric
Externí odkaz:
https://doaj.org/article/4efb43aa91e44297b215972e7b971f82
Autor:
Michael J Metzger, Stephen P Goff
Publikováno v:
PLoS Pathogens, Vol 12, Iss 10, p e1005904 (2016)
Externí odkaz:
https://doaj.org/article/f54f11e72f8c46738f91e376786efe9b
Autor:
Jie Gao, Shannon M Buckley, Luisa Cimmino, Maria Guillamot, Alexandros Strikoudis, Yong Cang, Stephen P Goff, Iannis Aifantis
Publikováno v:
eLife, Vol 4 (2015)
Little is known on post-transcriptional regulation of adult and embryonic stem cell maintenance and differentiation. Here we characterize the role of Ddb1, a component of the CUL4-DDB1 ubiquitin ligase complex. Ddb1 is highly expressed in multipotent
Externí odkaz:
https://doaj.org/article/cbf3b56002334b0fa04be2cb19038c6d
Publikováno v:
PLoS Pathogens, Vol 7, Iss 4, p e1002019 (2011)
Human TRIM5α potently restricts particular strains of murine leukemia viruses (the so-called N-tropic strains) but not others (the B- or NB-tropic strains) during early stages of infection. We show that overexpression of SUMO-1 in human 293T cells,
Externí odkaz:
https://doaj.org/article/05e2f706254c4c9cb81d9b4ab0376e9f
Autor:
Frederic D Bushman, Nirav Malani, Jason Fernandes, Iván D'Orso, Gerard Cagney, Tracy L Diamond, Honglin Zhou, Daria J Hazuda, Amy S Espeseth, Renate König, Sourav Bandyopadhyay, Trey Ideker, Stephen P Goff, Nevan J Krogan, Alan D Frankel, John A T Young, Sumit K Chanda
Publikováno v:
PLoS Pathogens, Vol 5, Iss 5, p e1000437 (2009)
We have analyzed host cell genes linked to HIV replication that were identified in nine genome-wide studies, including three independent siRNA screens. Overlaps among the siRNA screens were very modest (
Externí odkaz:
https://doaj.org/article/8367ca4bba4e49f2bad41a3007e87ed2
Publikováno v:
Viruses, Vol 15, Iss 2, p 474 (2023)
Host factor tRNAs facilitate the replication of retroviruses such as human immunodeficiency virus type 1 (HIV-1). HIV-1 uses human tRNALys3 as the primer for reverse transcription, and the assembly of HIV-1 structural protein Gag at the plasma membra
Externí odkaz:
https://doaj.org/article/b5891c381b9f4cb7a210349f98c6dc9b
Autor:
Huijuan Liu, Ping Li, Shaoyang Zhang, Jinnan Xiang, Ruichen Yang, Jiajia Liu, Md Shafiquzzaman, Soma Biswas, Zhanying Wei, Zhenlin Zhang, Xin Zhou, Feng Yin, Yangli Xie, Stephen P. Goff, Lin Chen, Baojie Li
Publikováno v:
Nature Genetics. 54:1946-1958
Specialized connective tissues, including bone and adipose tissues, control various physiological activities, including mineral and energy homeostasis. However, the identity of stem cells maintaining these tissues throughout adulthood remains elusive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4cbe3f12e00c4c41a67d2dbd70f5a97
https://doi.org/10.1038/s41588-022-01227-4
https://doi.org/10.1038/s41588-022-01227-4
Autor:
Marlene V. Buckmaster, Stephen P. Goff
Publikováno v:
J Virol
The zinc finger antiviral protein (ZAP) is an interferon-stimulated gene (ISG) with potent intrinsic antiviral activity. ZAP inhibits the replication of retroviruses, including murine leukemia virus (MLV) and HIV-1, as well as alphaviruses, filovirus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35f39c42dac654977609ae7387757be3
https://doi.org/10.1128/jvi.00526-22
https://doi.org/10.1128/jvi.00526-22