Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Stephen P Diggle"'
Autor:
Gavin Melaugh, Jaime Hutchison, Kasper Nørskov Kragh, Yasuhiko Irie, Aled Roberts, Thomas Bjarnsholt, Stephen P Diggle, Vernita D Gordon, Rosalind J Allen
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0149683 (2016)
Bacterial biofilms are usually assumed to originate from individual cells deposited on a surface. However, many biofilm-forming bacteria tend to aggregate in the planktonic phase so that it is possible that many natural and infectious biofilms origin
Externí odkaz:
https://doaj.org/article/d561ec7f0fa0424f80bd4fcfe13a7f07
Autor:
Natalie Jiricny, Søren Molin, Kevin Foster, Stephen P Diggle, Pauline D Scanlan, Melanie Ghoul, Helle Krogh Johansen, Lorenzo A Santorelli, Roman Popat, Stuart A West, Ashleigh S Griffin
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e83124 (2014)
Pseudomonas aeruginosa, is an opportunistic, bacterial pathogen causing persistent and frequently fatal infections of the lung in patients with cystic fibrosis. Isolates from chronic infections differ from laboratory and environmental strains in a ra
Externí odkaz:
https://doaj.org/article/f91f498b41cd4b4c9bb09218f2299442
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95929 (2014)
Combinatorial communication, in which two signals are used together to achieve an effect that is different to the sum of the effects of the component parts, is apparently rare in nature: it is ubiquitous in human language, appears to exist in a simpl
Externí odkaz:
https://doaj.org/article/6a532a64b7ef4cfc803bbbe4a2970629
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT Pseudomonas aeruginosa is an opportunistic pathogen which causes chronic, drug-resistant lung infections in cystic fibrosis (CF) patients. In this study, we explore the role of genomic diversification and evolutionary trade-offs in antimicro
Externí odkaz:
https://doaj.org/article/7b74583486714893a47a6b6a5f636bb8
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT Chronic, highly antibiotic-resistant infections in cystic fibrosis (CF) lungs contribute to increasing morbidity and mortality. Pseudomonas aeruginosa, a common CF pathogen, exhibits resistance to multiple antibiotics, contributing to antimi
Externí odkaz:
https://doaj.org/article/747b98ce2eef482c8eaf355ee9e7b694
Publikováno v:
Frontiers in Microbiology, Vol 13 (2023)
Solventogenic clostridia represent a diverse group of anaerobic, spore-forming bacteria capable of producing acetone, butanol and ethanol through their unique biphasic metabolism. An intrinsic problem with these organisms however is their tendency to
Externí odkaz:
https://doaj.org/article/d48c08edafee46cca0214a0068821778
Pseudomonas aeruginosais a prevalent pathogen in cystic fibrosis (CF) lungs which displays strong resistance to various antibiotic classes, contributing to antimicrobial resistance (AMR).P aeruginosapopulations in CF lungs exhibit considerable geneti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da578e10f3ac3fcd0823059c5d2390c6
https://doi.org/10.1101/2023.04.26.538445
https://doi.org/10.1101/2023.04.26.538445
Autor:
Katherine L. Cook, David R. Soto-Pantoja, Stephen P. Diggle, Shaina A. Yates-Alston, Nicole Levi-Polyachenko, Edward A. Levine, Marissa Howard-McNatt, Adam S. Wilson, Kenysha Y.J. Clear, Christine Velazquez, Alaa Bawaneh, Akiko Chiba
Breast tumors have their own specific microbiota, distinct from normal mammary gland tissue. Patients with breast cancer that present with locally advanced disease often undergo neoadjuvant chemotherapy to reduce tumor size prior to surgery to allow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce07e9c95e2ecf0b37289ea1c2999e4e
https://doi.org/10.1158/1541-7786.c.6541044.v1
https://doi.org/10.1158/1541-7786.c.6541044.v1
Autor:
Katherine L. Cook, David R. Soto-Pantoja, Stephen P. Diggle, Shaina A. Yates-Alston, Nicole Levi-Polyachenko, Edward A. Levine, Marissa Howard-McNatt, Adam S. Wilson, Kenysha Y.J. Clear, Christine Velazquez, Alaa Bawaneh, Akiko Chiba
Obesity influences breast tumor microbiota populations. Breast tumor 16S sequencing results were stratified based upon patient body mass index (BMI). Tumor bacterial populations from non-obese patients with a BMI of 20-27 (n=9) were compared with bac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c577226eb8b99608dd5b4fe380b729
https://doi.org/10.1158/1541-7786.22515330.v1
https://doi.org/10.1158/1541-7786.22515330.v1
Publikováno v:
Microbiology (Reading)
Pseudomonas aeruginosa uses quorum sensing (QS) to coordinate the expression of multiple genes necessary for establishing and maintaining infection. It has previously been shown that lasR QS mutations frequently arise in cystic fibrosis (CF) lung inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c0f027a01e38444df238bbdab94ead5
https://doi.org/10.1099/mic.0.001265
https://doi.org/10.1099/mic.0.001265