Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Stephen P, Sugrue"'
Autor:
Shu-Kay Ng, Stephen P. Sugrue, Stephen Kw Tsui, William R. Welch, Michael G. Muto, Junzheng Yang, Pui-Wah Choi, Minghua Liu, Margit Singh, Ross S. Berkowitz, Shu-Wing Ng, Yanli Zhang, Jamie Sui-Lam Kwok
Publikováno v:
Oncotarget
ResearcherID
ResearcherID
// Yanli Zhang 1 , Jamie Sui-Lam Kwok 2 , Pui-Wah Choi 1 , Minghua Liu 2 , Junzheng Yang 1 , Margit Singh 1 , Shu-Kay Ng 4 , William R. Welch 5 , Michael G. Muto 1 , Stephen KW Tsui 2 , Stephen P. Sugrue 3 , Ross S. Berkowitz 1 , Shu-Wing Ng 1 1 Labo
Autor:
Jinrong Min, Guoliang Xu, Erin A. Clark, Chuanbing Bian, Ursula B. Kaiser, Yoichi Kato, Yufei Xu, Chun Ma, Di Hu, Chao Xu, Qingyan Cui, Feizhen Wu, José G. Abreu, Bin Zhao, Tanja Cerovina, Andrew Barbara, X. Shirley Liu, Gert Jan C. Veenstra, Housheng Hansen He, Yujiang Geno Shi, Wolfram Tempel, Akiko Kato, Yeguang Hu, Stephen P. Sugrue, Xi He, Jianbo Diao
Publikováno v:
Cell, 151, 1200-1213
Cell, 151, 6, pp. 1200-1213
Cell, 151, 6, pp. 1200-1213
Ten-Eleven Translocation (Tet) family of dioxygenases offers a new mechanism for dynamic regulation of DNA methylation and has been implicated in cell lineage differentiation and oncogenesis. Yet their functional roles and mechanisms of action in gen
Publikováno v:
Molecular Vision
Purpose The specialized corneal epithelium requires differentiated properties, specific for its role at the anterior surface of the eye. Thus, tight maintenance of the differentiated qualities of the corneal epithelial is essential. Pinin (PNN) is an
Autor:
Gustavo C. Munguba, Marguerite E. Hunt, Yang Shi, Roman Alpatov, Stephen P. Sugrue, Jeong-Hoon Joo, Paul W. Caton, Yujiang Shi
Publikováno v:
Molecular and Cellular Biology. 24:10223-10235
Previously, we have shown that pinin/DRS (Pnn), a 140-kDa nuclear and cell adhesion-related phosphoprotein, is involved in the regulation of cell adhesion and modulation of the activity of multiple tumor suppressor genes. In the nucleus Pnn is concen
Autor:
Yanli Zhang, Jamie Sui-Lam Kwok, Pui-Wah Choi, Minghua Liu, Junzheng Yang, Margit Singh, Shu-Kay Ng, William R. Welch, Michael G. Muto, Stephen KW Tsui, Stephen P. Sugrue, Ross S. Berkowitz, Shu-Wing Ng
Publikováno v:
Oncotarget
Unlike many other human solid tumors, ovarian tumors express many epithelial markers at a high level for cell growth and local invasion. The phosphoprotein Pinin plays a key role in epithelial cell identity. We showed that clinical ovarian tumors and
Autor:
Stephen P. Sugrue, Jia Shi
Publikováno v:
Journal of Biological Chemistry. 275:14910-14915
Pinin is a cell adhesion-associated and nuclear protein that has been shown to localize in the vicinity of intermediate filament (IF) convergence upon the cytoplasmic face of the desmosomal plaque as well as in the nucleus. The localization of pinin
Autor:
Jonathan D. Licht, Yang Shi, Raymond H. See, V M Rangnekar, Ricky W. Johnstone, S Muthukkumar, Christoph Englert, Stephen P. Sugrue, James C. Wang, Thomas M. Roberts, S F Sells, Daniel A. Haber
Publikováno v:
Molecular and Cellular Biology. 16:6945-6956
The tumor suppressor WT1 represses and activates transcription. The loss and/or imbalance of the dual transcriptional activity of WT1 may contribute to Wilms' tumor. In this study, we identified par-4 (for prostate apoptosis response) as a WT1-intera
Publikováno v:
Blood. 87:4596-4606
We dissected the functions of the microenvironment of bone marrow (BM) and fetal liver (FL) at the cellular level by cloning individual stromal calls and characterizing their phenotypical and functional features. Stromal cell clones derived from FL a
Publikováno v:
Ophthalmology. 101:174-181
Purpose: Patients with the floppy eyelid syndrome have chronic papillary conjunctivitis with easily everted upper eyelids and a soft, pliant upper tarsus. The purpose of this study is to describe the clinical features and the histopathologic correlat
Autor:
Stephen P. Sugrue, P Ouyang
Publikováno v:
The Journal of Cell Biology
Using a mAb, referred to as 08L, we have identified a protein, of M(r) approximately 140,000, associated with desmosomes of epithelial cells. The 08L antibody stained the intracellular side of lateral cell margins of monolayer epithelial cells but di