Zobrazeno 1 - 10
of 187
pro vyhledávání: '"Stephen P, McAdoo"'
Autor:
Frederick W.K. Tam, James Tumlin, Jonathan Barratt, Brad H. Rovin, Ian S.D. Roberts, Candice Roufosse, H. Terence Cook, Gurjeet Bhangal, Alison L. Brown, Martin Busch, Fayaz Dudhiya, Anne-Marie Duliege, Donald J. Fraser, Daniel P. Gale, Chiu-Ching Huang, Ping-Chin Lai, Meng Lee, Esteban S. Masuda, Stephen P. McAdoo, Alexander R. Rosenkranz, Claudia Sommerer, Gere Sunder-Plassmann, Cheuk-Chun Szeto, Sydney C.W. Tang, Don E. Williamson, Lisa Willcocks, Volker Vielhauer, Min Jeong Kim, Leslie Todd, Hany Zayed, Sandra Tong-Starksen, Richard Lafayette
Publikováno v:
Kidney International Reports, Vol 8, Iss 12, Pp 2546-2556 (2023)
Introduction: We reported increased spleen tyrosine kinase (SYK) expression in kidney biopsies of patients with IgA nephropathy (IgAN) and that inhibition of SYK reduces inflammatory cytokines production from IgA stimulated mesangial cells. Methods:
Externí odkaz:
https://doaj.org/article/66982ca5bf66483cb14ee295eaf07526
Autor:
Jack S. Gisby, Norzawani B. Buang, Artemis Papadaki, Candice L. Clarke, Talat H. Malik, Nicholas Medjeral-Thomas, Damiola Pinheiro, Paige M. Mortimer, Shanice Lewis, Eleanor Sandhu, Stephen P. McAdoo, Maria F. Prendecki, Michelle Willicombe, Matthew C. Pickering, Marina Botto, David C. Thomas, James E. Peters
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
End-stage kidney disease confers a high risk for severe COVID-19 infection. Using an at-risk group (end-stage kidney disease patients with COVID-19), authors using RNA-sequencing of immune cells and plasma proteomic profiling to investigate the host
Externí odkaz:
https://doaj.org/article/6195c991b86743c2bc2cea16ffcb650a
Autor:
Shenzhen Tempest-Roe, Maria Prendecki, Stephen P. McAdoo, Candice Clarke, Anisha Tanna, Tabitha Turner-Stokes, Esteban S. Masuda, Michelle Willicombe, H. Terence Cook, Candice Roufosse, David Taube, Charles D. Pusey, Frederick W. K. Tam
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Antibody mediated rejection is a major cause of renal allograft loss. Circulating preformed donor specific antibodies (DSA) can result as a consequence of blood transfusion, pregnancy or prior transplantation. Current treatment strategies ar
Externí odkaz:
https://doaj.org/article/657abd7f4c754b5aa4ed59b73337583f
Autor:
Tina Thomson, Maria Prendecki, Sarah Gleeson, Paul Martin, Katrina Spensley, Rute Cardoso De Aguiar, Bynvant Sandhu, Charlotte Seneschall, Jaslyn Gan, Candice L. Clarke, Shanice Lewis, Graham Pickard, David Thomas, Stephen P. McAdoo, Liz Lightstone, Alison Cox, Peter Kelleher, Michelle Willicombe
Publikováno v:
EClinicalMedicine, Vol 53, Iss , Pp 101642- (2022)
Summary: Background: Solid organ transplant recipients have attenuated immune responses to SARS-CoV-2 vaccines. In this study, we report on immune responses to 3rd- (V3) and 4th- (V4) doses of heterologous and homologous vaccines in a kidney transpla
Externí odkaz:
https://doaj.org/article/4879b50c9f754096b64b6ff9caf5fbc2
Autor:
Paul Martin, Sarah Gleeson, Candice L. Clarke, Tina Thomson, Helena Edwards, Katrina Spensley, Paige Mortimer, Stacey McIntyre, Alison Cox, Graham Pickard, Liz Lightstone, David Thomas, Stephen P. McAdoo, Peter Kelleher, Maria Prendecki, Michelle Willicombe
Publikováno v:
The Lancet Regional Health. Europe, Vol 21, Iss , Pp 100478- (2022)
Summary: Background: People with end-stage kidney disease, including people on haemodialysis, are susceptible to greater COVID-19 related morbidity and mortality. This study compares the immunogenicity and clinical effectiveness of BNT162B2 versus Ch
Externí odkaz:
https://doaj.org/article/dca0c46f18974f1b8561576518435e95
Autor:
Sung Soo Ahn, Taejun Yoon, Yong-Beom Park, Maria Prendecki, Gurjeet Bhangal, Stephen P. McAdoo, Sang-Won Lee
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-12 (2021)
Abstract Background To investigate whether serum chitinase-3-like 1 protein (YKL-40) is associated with disease activity in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). Methods ELISA was performed in serum samples from AAV
Externí odkaz:
https://doaj.org/article/11cc781866a74bf8ad88de1e01c93f8c
Autor:
Aikaterini Nikolopoulou, Isabel Huang-Doran, Stephen P. McAdoo, Megan E. Griffith, H. Terence Cook, Charles D. Pusey
Publikováno v:
Kidney International Reports, Vol 4, Iss 11, Pp 1577-1584 (2019)
Introduction: Membranous glomerulonephritis (MGN) is rarely associated with necrotizing and crescentic glomerulonephritis (NCGN). Methods: We report the clinical and pathologic findings in 15 patients with MGN and NCGN associated with anti-neutrophil
Externí odkaz:
https://doaj.org/article/de230865076a4f8ea45340f7efda6656
Autor:
Nicholas R. Medjeral-Thomas, Anne Troldborg, Annette G. Hansen, Jack Gisby, Candice L. Clarke, Maria Prendecki, Stephen P. McAdoo, Eleanor Sandhu, Liz Lightstone, David C. Thomas, Michelle Willicombe, Marina Botto, James E. Peters, Matthew C. Pickering, Steffen Thiel
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
We do not understand why non-white ethnicity and chronic kidney disease increase susceptibility to COVID-19. The lectin pathway of complement activation is a key contributor to innate immunity and inflammation. Concentrations of plasma lectin pathway
Externí odkaz:
https://doaj.org/article/f1fcae5986ee451d9f771a6f71f26323
Autor:
Jack Gisby, Candice L Clarke, Nicholas Medjeral-Thomas, Talat H Malik, Artemis Papadaki, Paige M Mortimer, Norzawani B Buang, Shanice Lewis, Marie Pereira, Frederic Toulza, Ester Fagnano, Marie-Anne Mawhin, Emma E Dutton, Lunnathaya Tapeng, Arianne C Richard, Paul DW Kirk, Jacques Behmoaras, Eleanor Sandhu, Stephen P McAdoo, Maria F Prendecki, Matthew C Pickering, Marina Botto, Michelle Willicombe, David C Thomas, James E Peters
Publikováno v:
eLife, Vol 10 (2021)
End-stage kidney disease (ESKD) patients are at high risk of severe COVID-19. We measured 436 circulating proteins in serial blood samples from hospitalised and non-hospitalised ESKD patients with COVID-19 (n = 256 samples from 55 patients). Comparis
Externí odkaz:
https://doaj.org/article/bbf513cf4b974a538355b6474ff58476
Autor:
Maria Prendecki, Candice Clarke, Tom McKinnon, Liz Lightstone, Matthew C. Pickering, David C. Thomas, Stephen P. McAdoo, Michelle Willicombe
Publikováno v:
Kidney Medicine, Vol 3, Iss 1, Pp 54-59.e1 (2021)
Rationale & Objective: A number of serologic tests for immunoglobulin G (IgG) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are now commercially available, including multiple lateral flow immunoassays (LFIAs), which have the ad
Externí odkaz:
https://doaj.org/article/b0dab4c18d1c4db1b9d7c401fca635b3