Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Stephen N. Mueller"'
Autor:
William S. Groene, Jeffrey A. Miller, James D. O'Neil, Stephen N. Mueller, Michael K. Bamat, Robert M. Lorence, M. Scot Roberts
Publikováno v:
Current Cancer Drug Targets. 7:157-167
PV701 is a naturally-attenuated, non-recombinant, oncolytic strain of Newcastle disease virus that displays preclinical intravenous (IV) efficacy. PV701 is selective at killing human cancer cells versus normal human cells based on tumor specific defe
Publikováno v:
Journal of Applied Physiology. 74:1581-1590
The addition of adenosine to perfusates flowing through an in vitro cell-column model of the vasculature decreases the permeability of cell column fetal bovine aortic endothelial monolayers. At 10(-4) M adenosine, cell monolayer permeability to the p
Autor:
Kellie Nader, David L. Ennist, Gary Kikuchi, Chris Lockey, Tracey Grooms, Stephen N. Mueller, Stephen G. Marcus, Irina Burimski, Zhifeng Long, Patricia Ryan, Lie-Ping Li, Gerard J. McGarrity, Edward Otto, Ihor Mychkovsky
Publikováno v:
Human gene therapy. 9(8)
Patients with recurrent malignant brain cancer, who were receiving gene therapy by intracerebral injection of murine retroviral vector producer cells (VPCs), were monitored for the presence of replication-competent retrovirus (RCR). RCR sequences wer
Autor:
Edward Otto, Elio F. Vanin, Agnes Jones-Trower, W. French Anderson, Kathy Stambaugh, Gerard J. McGarrity, Stephen N. Mueller
Publikováno v:
Human gene therapy. 5(5)
A replication-competent retrovirus (RCR) was detected by S+/L- assays in three lots of retroviral vector G1Na that were harvested on consecutive days from a single culture of PA317/G1Na producer cells. Using a number of retrovirus-specific primer pai
Autor:
Carole I. Bradt, Stephen N. Mueller, Diane R. Umbenhauer, Timothy E. Johnson, Warren W. Nichols, Rosina Hill, Elliot M. Levine
Publikováno v:
Journal of cellular physiology. 150(1)
Karyotypic and phenotypic changes were found in human adult endothelial cells (EC) during aging in vitro. A trisomy of chromosome 11 was found in 11 out of 12 EC cultures examined, derived from 9 cell lines from 8 donors. The incidence of this trisom
Autor:
Warren W. Nichols, Buynak Eb, Carole I. Bradt, Rosina Hill, Elliot M. Levine, Margaret M. Aronson, Stephen N. Mueller, Bruce E. Jarrell
Publikováno v:
Journal of Cellular Physiology. 132:453-462
Cytogenetic evaluation of serially subcultivated human endothelial cells revealed significant differences between cultures derived from fetal umbilical cords and cultures derived from various vessel sites in adults. A rapid increase in the prevalence
Autor:
Stephen N. Mueller, J. M. McNiff, Alfred P. Fishman, Frederick R. Haselton, Elliot M. Levine, Stuart K. Williams, Phyllis M. Sampson, Steven M. Albelda
Publikováno v:
Journal of Applied Physiology. 64:308-322
The purpose of this study was to characterize the permeability characteristics of an in vitro endothelial cell monolayer system and relate this information to available in vivo data. We cultured bovine fetal aortic endothelial cells on fibronectin-co
Autor:
Sandor S. Shapiro, R. Anthony Carabasi, Stephen N. Mueller, Stuart K. Williams, Bruce E. Jarrell, Elliot M. Levine, Susan C. Thornton
Publikováno v:
Journal of Vascular Surgery. 1:757-764
The purpose of the present study was to culture human adult endothelial cells (HAECs) on a long-term basis in the laboratory. Previous inability to accomplish this has been the major impediment to the in vitro study of endothelialization of prostheti
Publikováno v:
Journal of Cellular Physiology. 140:439-448
The effects of heparin and other glycosaminoglycans (GAGs) on the mitogenicity and stability of acidic fibroblast growth factor (aFGF) were studied. The mitogenic activity of aFGF was assayed utilizing cultured adult human endothelial cells (AHECs) i
Publikováno v:
Journal of Cellular Physiology. 131:1-5
Bovine fetal aortic endothelial cells cultured in serum-containing medium accumulate angiotensin I-converting enzyme (ACE) activity and also release it into the culture medium. Following subcultivation of a confluent culture using trypsin-EDTA, cellu