Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Stephen N. Birrell"'
Autor:
Margaret M. Centenera, Theresa E. Hickey, Shalini Jindal, Natalie K. Ryan, Preethi Ravindranathan, Hisham Mohammed, Jessica L. Robinson, Matthew J. Schiewer, Shihong Ma, Payal Kapur, Peter D. Sutherland, Clive E. Hoffmann, Claus G. Roehrborn, Leonard G. Gomella, Jason S. Carroll, Stephen N. Birrell, Karen E. Knudsen, Ganesh V. Raj, Lisa M. Butler, Wayne D. Tilley
Publikováno v:
Molecular Oncology, Vol 12, Iss 9, Pp 1608-1622 (2018)
Breast and prostate cancer research to date has largely been predicated on the use of cell lines in vitro or in vivo. These limitations have led to the development of more clinically relevant models, such as organoids or murine xenografts that utiliz
Externí odkaz:
https://doaj.org/article/0552f838da6a4c13b4e0ce9e34c20273
Autor:
Wayne D. Tilley, Theresa E. Hickey, Carlo Palmieri, Robert L. Sutherland, Stephen N. Birrell, David G. Huntsman, Sarah L. Vowler, Alexandra I. Ruiz, Andrew J. Sakko, Ewan K.A. Millar, Esmaeil Ebrahimie, Sandra A. O'Toole, Catriona M. McNeil, Samuel Leung, Lisa M. Butler, Shalini Jindal, Tina Bianco-Miotto, Carmela Ricciardelli
Purpose: Consensus is lacking regarding the androgen receptor (AR) as a prognostic marker in breast cancer. The objectives of this study were to comprehensively review the literature on AR prognostication and determine optimal criteria for AR as an i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab858ec386aa4731623a65732a1881c8
https://doi.org/10.1158/1078-0432.c.6526020.v1
https://doi.org/10.1158/1078-0432.c.6526020.v1
Autor:
Wayne D. Tilley, Theresa E. Hickey, Carlo Palmieri, Robert L. Sutherland, Stephen N. Birrell, David G. Huntsman, Sarah L. Vowler, Alexandra I. Ruiz, Andrew J. Sakko, Ewan K.A. Millar, Esmaeil Ebrahimie, Sandra A. O'Toole, Catriona M. McNeil, Samuel Leung, Lisa M. Butler, Shalini Jindal, Tina Bianco-Miotto, Carmela Ricciardelli
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::134a8376bd734fdec422b72fe11248c3
https://doi.org/10.1158/1078-0432.22465434.v1
https://doi.org/10.1158/1078-0432.22465434.v1
Autor:
Wayne D. Tilley, Theresa E. Hickey, Carlo Palmieri, Robert L. Sutherland, Stephen N. Birrell, David G. Huntsman, Sarah L. Vowler, Alexandra I. Ruiz, Andrew J. Sakko, Ewan K.A. Millar, Esmaeil Ebrahimie, Sandra A. O'Toole, Catriona M. McNeil, Samuel Leung, Lisa M. Butler, Shalini Jindal, Tina Bianco-Miotto, Carmela Ricciardelli
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61563ab9c221a99f03ffab405636fcc9
https://doi.org/10.1158/1078-0432.22465425
https://doi.org/10.1158/1078-0432.22465425
Autor:
Wayne D. Tilley, Theresa E. Hickey, Carlo Palmieri, Robert L. Sutherland, Stephen N. Birrell, David G. Huntsman, Sarah L. Vowler, Alexandra I. Ruiz, Andrew J. Sakko, Ewan K.A. Millar, Esmaeil Ebrahimie, Sandra A. O'Toole, Catriona M. McNeil, Samuel Leung, Lisa M. Butler, Shalini Jindal, Tina Bianco-Miotto, Carmela Ricciardelli
Supplementary Figures 1-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39ee36371e42578c4358fff1b65cb2e3
https://doi.org/10.1158/1078-0432.22465431.v1
https://doi.org/10.1158/1078-0432.22465431.v1
Data from Androgen Receptor Inhibits Estrogen Receptor-α Activity and Is Prognostic in Breast Cancer
Autor:
Wayne D. Tilley, Lisa M. Butler, Robert L. Sutherland, Gerhard A. Coetzee, Stephen N. Birrell, Susan M. Henshall, Nicole L. Moore, Li Jia, Davendra Segara, Shalini Jindal, Jonathan M. Harris, Margaret M. Centenera, Tina Bianco-Miotto, Carmela Ricciardelli, Grant Buchanan, Amelia A. Peters
There is emerging evidence that the balance between estrogen receptor-α (ERα) and androgen receptor (AR) signaling is a critical determinant of growth in the normal and malignant breast. In this study, we assessed AR status in a cohort of 215 invas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cbbdcc61436f992004732e61c07f12e
https://doi.org/10.1158/0008-5472.c.6498573.v1
https://doi.org/10.1158/0008-5472.c.6498573.v1
Autor:
Wayne D. Tilley, Lisa M. Butler, Robert L. Sutherland, Gerhard A. Coetzee, Stephen N. Birrell, Susan M. Henshall, Nicole L. Moore, Li Jia, Davendra Segara, Shalini Jindal, Jonathan M. Harris, Margaret M. Centenera, Tina Bianco-Miotto, Carmela Ricciardelli, Grant Buchanan, Amelia A. Peters
Supplementary Tables 1-3 from Androgen Receptor Inhibits Estrogen Receptor-α Activity and Is Prognostic in Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::843e0fa94a2825e92f49391f58ac2b37
https://doi.org/10.1158/0008-5472.22377411.v1
https://doi.org/10.1158/0008-5472.22377411.v1
Autor:
Geraldine Laven-Law, Wilbert Zwart, Tarek M. A. Abdel-Fatah, Theresa E. Hickey, Mun N. Hui, Sarah Alexandrou, Luke A. Selth, Kee Ming Chia, Ian O. Ellis, C. Elizabeth Caldon, Daniel L. Roden, Jessica Finlay-Schultz, Suzan Stelloo, Shalini Jindal, Alexander Swarbrick, Wayne D. Tilley, Stephen N. Birrell, Carol A. Sartorius, Heloisa Helena Milioli, Richard Iggo, Carlo Palmieri, Esmaeil Ebrahimie, Jason S. Carroll, Elgene Lim
Publikováno v:
Nature Medicine, 27, pp. 310-320
Nature Medicine, 27, 310-320
NATURE MEDICINE
Nature Medicine, 27, 310-320
NATURE MEDICINE
The role of the androgen receptor (AR) in estrogen receptor (ER)-α-positive breast cancer is controversial, constraining implementation of AR-directed therapies. Using a diverse, clinically relevant panel of cell-line and patient-derived models, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fba0daa407197cbaf1a818ceffe24eb8
https://doi.org/10.1038/s41591-020-01168-7
https://doi.org/10.1038/s41591-020-01168-7
Autor:
Charles L. Vogel, Robert H. Getzenberg, Mitchell S. Steiner, Kirti Jain, Carlo Palmieri, Patrick Wayne Cobb, Hope S. Rugo, Elgene Lim, Adam Brufsky, Hannah M. Linden, Beth Overmoyer, Joyce O'Shaughnessy, Lee S. Schwartzberg, Stephen N. Birrell
Publikováno v:
Cancer Research. 81:PD8-10
Introduction: Hormonal agents remain the most effective therapies for estrogen receptor positive (ER+) HER2- breast cancer. The androgen receptor (AR) is the most highly expressed steroid receptor found in up to 95% of ER+ breast cancer patients. And
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ca5431ae002f95e0eae21f92fcb7c60
https://doi.org/10.1158/1538-7445.sabcs20-pd8-10
https://doi.org/10.1158/1538-7445.sabcs20-pd8-10
Autor:
Roberto A. Leon-Ferre, W Mitchell, J Le-Rademacher, P Novotni, Charles L. Loprinzi, R Glaser, Copur, S Terstriep, S Page, C Jones, Stephen N. Birrell, Armando E. Giuliano
Publikováno v:
Cancer Research. 79:P4-16
Background: Aromatase inhibitors are a mainstay hormone receptor-positive breast cancer treatment. AIA occur in up to 50% of patients (pts), adversely affecting quality of life and treatment compliance. A small phase II clinical trial of oral testost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96bca013a6168fc81aac8b2c8ccb6b95
https://doi.org/10.1158/1538-7445.sabcs18-p4-16-01
https://doi.org/10.1158/1538-7445.sabcs18-p4-16-01