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pro vyhledávání: '"Stephen Martin Pederson"'
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-19 (2020)
Abstract To prevent or delay the onset of Alzheimer’s disease (AD), we must understand its molecular basis. The great majority of AD cases arise sporadically with a late onset after 65 years of age (LOAD). However, rare familial cases of AD can occ
Externí odkaz:
https://doaj.org/article/a77336e36364429eb02a9ed52eaa0bd5
Autor:
Haowei Jiang, Stephen Martin Pederson, Morgan Newman, Yang Dong, Karissa Barthelson, Michael Lardelli
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0232559 (2020)
PRESENILIN 2 (PSEN2) is one of the genes mutated in early onset familial Alzheimer's disease (EOfAD). PSEN2 shares significant amino acid sequence identity with another EOfAD-related gene PRESENILIN 1 (PSEN1), and partial functional redundancy is see
Externí odkaz:
https://doaj.org/article/f3d764ecaf404281bce6c40db04bb073
BackgroundGenome-wide association studies (GWAS) have enabled the discovery of single nucleotide polymorphisms (SNPs) that are significantly associated with many autoimmune diseases including type 1 diabetes (T1D). However, many of the identified var
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1bd0da27580d3e77b7589b014bb23a5
https://doi.org/10.21203/rs.3.rs-1175572/v1
https://doi.org/10.21203/rs.3.rs-1175572/v1