A Fox2-dependent fatty acid ß-oxidation pathway coexists both in peroxisomes and mitochondria of the ascomycete yeast Candida lusitaniae.

Autor: Frédéric Gabriel, Isabelle Accoceberry, Jean-Jacques Bessoule, Bénédicte Salin, Marine Lucas-Guérin, Stephen Manon, Karine Dementhon, Thierry Noël

Publikováno v: PLoS ONE, Vol 9, Iss 12, p e114531 (2014)

It is generally admitted that the ascomycete yeasts of the subphylum Saccharomycotina possess a single fatty acid ß-oxidation pathway located exclusively in peroxisomes, and that they lost mitochondrial ß-oxidation early during evolution. In this w

Externí odkaz: https://doaj.org/article/a20d8b4510454ee291f1277a62359893

Bcl-2 expression stimulates ethanol production in yeast

Autor: Laurent M. Dejean, Hailie Willey, Carlos Gonzalez, Sean Carpenter, Andrew Gilbert, Krish Krishnan, Stephen Manon

Publikováno v: Biophysical Journal. 122:94a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dffe0d042226c4982bf05c3a79392be5
https://doi.org/10.1016/j.bpj.2022.11.704

Non-phosphorylatable mutants of Ser184 lead to incomplete activation of Bax

Autor: Lilit Simonyan, Mathilde Gonin, James Hanks, Jordan Friedlein, Kevin Dutrec, Hubert Arokium, Akandé Rouchidane Eyitayo, Toukounou Megann Doudy, Stéphane Chaignepain, Stéphen Manon, Laurent Dejean

Publikováno v: Frontiers in Oncology, Vol 12 (2023)

The S184 residue of Bax is the target of several protein kinases regulating cell fate, including AKT. It is well-established that, in cellulo, the substitution of S184 by a non-phosphorylatable residue stimulates both the mitochondrial localization o

Externí odkaz: https://doaj.org/article/64d6b3d2d0bf4495bb4bb1c2dca1ceac

Relationship of Subunit 8 of Yeast ATP Synthase and the Inner Mitochondrial Membrane. Subunit 8 Variants Containing Multiple Lysine Residues in the Central Hydrophobic Domain Retain Function

Autor: Phillip Nagley, Stephen Manon, Ruby H. P. Law, Rodney J. Devenish, Theo Papakonstantinou

Publikováno v: European Journal of Biochemistry. 227:745-752

A molecular genetic approach has been used to test the proposition that the central hydrophobic domain of yeast mitochondrial ATP synthase subunit 8 represents a transmembrane stem in contact with the lipid bilayer. The rationale for this approach is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb6e2af28540b1701d9f872daccfda2
https://doi.org/10.1111/j.1432-1033.1995.tb20197.x

Structure and function of a mitochondrial late embryogenesis abundant protein are revealed by desiccation

Autor: Patrick Saulnier, Emeline Teyssier, Cécile Mangavel, David Macherel, Catherine Passirani, Nicole Payet, Marie-Hélène Avelange-Macherel, Michel Jaquinod, Stephen Manon, Dimitri Tolleter

Publikováno v: The Plant cell
The Plant cell, 2007, 19 (5), pp.1580-1589. ⟨10.1105/tpc.107.050104⟩
The Plant cell, American Society of Plant Biologists (ASPB), 2007, 19 (5), pp.1580-1589. ⟨10.1105/tpc.107.050104⟩

Few organisms are able to withstand desiccation stress; however, desiccation tolerance is widespread among plant seeds. Survival without water relies on an array of mechanisms, including the accumulation of stress proteins such as the late embryogene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58e883f2ec62e9971b611e1655857be2
https://hal.inrae.fr/hal-02667565