Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Stephen Malin"'
Autor:
Chang He, Huqiao Luo, Ana Coelho, Meng Liu, Qijing Li, Jing Xu, Alexander Krämer, Stephen Malin, Zuyi Yuan, Rikard Holmdahl
Publikováno v:
Redox Biology, Vol 57, Iss , Pp 102499- (2022)
Externí odkaz:
https://doaj.org/article/fcdc3fd9001643858764a67beb94be9b
Autor:
Chang He, Huqiao Luo, Ana Coelho, Meng Liu, Qijing Li, Jing Xu, Alexander Krämer, Stephen Malin, Zuyi Yuan, Rikard Holmdahl
Publikováno v:
Redox Biology, Vol 56, Iss , Pp 102422- (2022)
Defective reactive oxygen species (ROS) production by genetically determined variants of the NADPH oxidase 2 (NOX2) complex component, NCF4, leads to enhanced production of autoantibodies to collagen type II (COL2) and severe collagen-induced arthrit
Externí odkaz:
https://doaj.org/article/7a75ebf3855c41f6a4e5909bf8aeeb0e
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The initiation, commitment, and terminal differentiation of the B cell lineage is stringently controlled by the coordinated action of various transcription factors. Among these, Arid3a has previously been implicated in regulating early B lymphopoiesi
Externí odkaz:
https://doaj.org/article/477651a865d5404d81186f86eb1d55a0
Autor:
Markus Jaritz, Alexandra Schebesta, Qiong Sun, Hiromi Tagoh, Tanja A. Schwickert, Maria Fischer, Anja Ebert, Luisa Cochella, Adrian Liston, Chiara Alberti, Lesly Calderón, Meinrad Busslinger, Martina Minnich, Stephen Malin, Karina Schindler
Publikováno v:
Sci Immunol
The transcription factor Pax5 controls B cell development, but its role in mature B cells is largely enigmatic. Here, we demonstrated that the loss of Pax5 by conditional mutagenesis in peripheral B lymphocytes led to the strong reduction of B-1a, ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b9242dbdcec0cb05301d22528204573
https://doi.org/10.1126/sciimmunol.abg5003
https://doi.org/10.1126/sciimmunol.abg5003
Autor:
Alessandro L. Gallina, Göran K. Hansson, Maria Salagianni, M Centa, Evangelos Andreakos, Gabrielle Paulsson-Berne, Glykeria Karadimou, Peder S. Olofsson, Stephen Malin, Anton Gisterå
Publikováno v:
European Heart Journal. 41
Background The interplay between innate and adaptive immunity is involved in the cause of the life-threatening events in atherosclerosis, such as myocardial infarction and stroke. We have previously shown that higher levels of Toll-like receptor 7 (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8762bcf2e2e70e3dc5e266c7a84fcd3e
https://doi.org/10.1093/ehjci/ehaa946.3832
https://doi.org/10.1093/ehjci/ehaa946.3832
Autor:
Peder S. Olofsson, Sanna Hellberg, Matti Jauhiainen, Jari Metso, Stephen Malin, Quan-Zhen Li, Guangchun Chen, Valentina Manfè, Vladimir S. Shavva, Christoph J. Binder
Atherosclerosis is thought to be initiated by the sub-intimal retention of apolipoprotein-B containing lipoproteins within susceptible sites of the vasculature. Understanding this initiation is not possible with current legacy mouse models of atheros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d7c04fc9c375d8991b07868dab72a46
https://doi.org/10.1101/2020.09.02.279596
https://doi.org/10.1101/2020.09.02.279596
Autor:
Grace J Liu, Meinrad Busslinger, Andreas Bergthaler, Stephen Malin, Markus Jaritz, Miriam Wöhner, Benedikt Agerer
Publikováno v:
The Journal of Experimental Medicine
Journal of Experimental Medicine
Journal of Experimental Medicine
Due to cross-antagonism of the B cell factor Pax5 and plasma cell regulator Blimp1, it was hypothesized that plasma cells develop only upon Pax5 repression by Blimp1. Unexpectedly, Liu et al. show that ectopic Pax5 expression in plasma cells does not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7130c971a6ef647a0093bff8fb20ebc
http://europepmc.org/articles/PMC7596824
http://europepmc.org/articles/PMC7596824
Autor:
Daniel Y. Li, Ljubica Perisic Matic, Fredrik Wermeling, Ulf Hedin, Dorothee Atzler, Sanjay V. Boddul, Lars Maegdesfessel, Sanna Hellberg, Hong Jin, Changyan Sun, Nienke J Verzaal, Albert Busch, Göran K. Hansson, Lisa Hofste, Christoph J. Binder, Esther Lutgens, Stephen Malin, Daniel F. J. Ketelhuth, Roland Baumgartner, Monica Centa, Sara Lind Enoksson
Publikováno v:
Circulation, 139(21), 2466-2482. Lippincott Williams and Wilkins
Background: Atherosclerosis progression is modulated by interactions with the adaptive immune system. Humoral immunity can help protect against atherosclerosis formation; however, the existence, origin, and function of putative atherogenic antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::441772baf81dc4028b2982330288c1ff
https://pubmed.ncbi.nlm.nih.gov/30894016
https://pubmed.ncbi.nlm.nih.gov/30894016
Autor:
Sabrina Gruber, Monica Centa, Göran K. Hansson, Stephen Malin, Daniel F.J. Ketelhuth, Christoph J. Binder, Konstantinos A. Polyzos, Daniel Nilsson, Daniel K. Johansson
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Supplemental Digital Content is available in the text.
Objective— The V1 (VHS107.1.42) immunoglobulin heavy chain gene is thought to be critical in producing IgM natural antibodies of the T15-idiotype that protect against both atherosclerosis
Objective— The V1 (VHS107.1.42) immunoglobulin heavy chain gene is thought to be critical in producing IgM natural antibodies of the T15-idiotype that protect against both atherosclerosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35699c29bc003ac17bc8a49349e068d0
https://doi.org/10.1161/atvbaha.115.305990
https://doi.org/10.1161/atvbaha.115.305990
Autor:
Kajsa E. Prokopec, Anton Gisterå, Daniel K. Johansson, Göran K. Hansson, Albert Dahdah, Monica Centa, Katrin Habir, Mikael C. I. Karlsson, Nobuyo Maeda, Daniel F. J. Ketelhuth, Manasa G. Garimella, Lisa Hofste, Christoph J. Binder, Konstantinos A. Polyzos, Chris A. Tibbitt, Stephen Malin, Julian M. Stark, Jonathan M. Coquet
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38
Objective— Dyslipidemia is a component of the metabolic syndrome, an established risk factor for atherosclerotic cardiovascular disease, and is also observed in various autoimmune and chronic inflammatory conditions. However, there are limited oppo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::530a1b9ddd5e710d6109de3a1a6eb04b
https://doi.org/10.1161/atvbaha.118.310802
https://doi.org/10.1161/atvbaha.118.310802