Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Stephen M. W. Chang"'
Autor:
James E. McCormack, Nancy Sajjadi, Thomas W. Dubensky, James G. Respess, Joanne O'Dea, Trung K. Phuong, Carlos E. Ibanez, Judith Greengard, Philip Lee Sheridan, Margaret Dow Moore, Daniel J. de la Vega, Sybille L. Sauter, Kay Townsend, Kathy Nguyen, David A. Driver, Douglas J. Jolly, Andrea Lynn, Nicholas J. DePolo, Mordechai Bodner, Stephen M. W. Chang
Publikováno v:
Molecular Therapy. 2(3):262-275
For many applications, human clinical therapies using retroviral vectors still require many technological improvements in key areas of vector design and production. These improvements include higher unprocessed manufacturing titers, complement-resist
Autor:
Stephen M. W. Chang, Duane Brumm, James E. McCormack, Denise Mittelstaedt, Thomas W. Dubensky, Theresa A. Banks, John M. Polo, Kay Townsend, Barbara A. Belli, David A. Driver, Donald J. Catton, David Chi-Tang Hsu, Linda Karavodin, Mangala J. Hariharan
Publikováno v:
Journal of Virology. 72:950-958
Previously we reported the development of a plasmid DNA expression vector system derived from Sindbis virus (T. W. Dubensky, Jr., et al., J. Virol. 70:508–519, 1996). In vitro, such vectors exhibit high-level heterologous gene expression via self-a
Autor:
Mangala J. Hariharan, Sondra Schlesinger, David A. Driver, Kay Townsend, Stephen M. W. Chang, Silvia Perri, Steven J. Mento, Barbara A. Belli, John M. Polo, Ilya Frolov, Scott Sherrill, Thomas W. Dubensky, Douglas J. Jolly
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 96(8)
Alphavirus vectors are being developed for possible human vaccine and gene therapy applications. We have sought to advance this field by devising DNA-based vectors and approaches for the production of recombinant vector particles. In this work, we ge
Autor:
Douglas J. Jolly, Lee William Tsung-Liang, Steven J. Mento, David R. Milich, Stephen M. W. Chang, Kay Townsend, Catharina Hultgren, Greg Ronlov, Janice Hughes, Joanne O'Dea, Jean Alfonso, Ali Javadian, Carol-Gay Anderson, Matti Sällberg, Krishna K. Murthy, Robert W. Eason
Publikováno v:
Human gene therapy. 9(12)
Cytotoxic T lymphocyte (CTL) activity and CD4+ helper T cell responses to the hepatitis B virus (HBV) core antigen (HBcAg) have been implicated in clearance of acute and chronic HBV infections. We showed that intramuscular injections of a novel recom
Autor:
Douglas J. Jolly, Theresa A. Banks, John M. Polo, Duane Brumm, Sunil Chada, Thomas W. Dubensky, Emi M. Latham, David A. Driver, Stephen M. W. Chang, Steven J. Mento, Barbara A. Belli
Publikováno v:
Annals of the New York Academy of Sciences. 772
Publikováno v:
Proceedings of the National Academy of Sciences. 82:6860-6864
The shape change of sickled erythrocytes induced by electrical pulses was investigated under various experimental conditions using different suspending media. The purpose of this research is to find a set of conditions under which sickled erythrocyte
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 3(7)
A high titer retroviral vector containing the cDNA of human estrogen receptor (hER) was generated and used to transfer the hER gene into the rat 208F cell line. Southern blot analysis showed the integration of the provirus to be at a unique site and
Publikováno v:
Somatic cell and molecular genetics. 15(2)
Two amphotropic-based mouse retroviral vectors carrying the neomycin-resistance gene were used to infect four bovine cell lines. Two cell lines, bovine kidney and spleen cells, were refractory to the infection while two independent bovine cells of ap
Autor:
John J. Wasmuth, Stephen M. W. Chang
Publikováno v:
Somatic cell and molecular genetics. 10(2)
A novel type of temperature-sensitive protein synthetic mutant was isolated from V-79 Chinese hamster lung cells using an amino acid analog suicide selection. The expression of the temperature sensitive phenotype of the mutant is greatly affected by